Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Brendan Galvin"'
Autor:
Michelle Huang, Sarah Kingan, Douglas Shoue, Oanh Nguyen, Lutz Froenicke, Brendan Galvin, Christine Lambert, Ruqayya Khan, Chirag Maheshwari, David Weisz, Gareth Maslen, Helen Davison, Erez Lieberman Aiden, Jonas Korlach, Olga Dudchenko, Mary Ann McDowell, Stephen Richards
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-8 (2024)
Abstract Phlebotomine sand flies are the vectors of leishmaniasis, a neglected tropical disease. High-quality reference genomes are an important tool for understanding the biology and eco-evolutionary dynamics underpinning disease epidemiology. Previ
Externí odkaz:
https://doaj.org/article/ba4febc13c8642608ddf3f0102c33039
Autor:
Brendan Galvin
Partway to Geophany, the latest collection by celebrated poet Brendan Galvin, chronicles the waxing and waning of the year in a small seacoast town on Cape Cod, alongside observations of other beloved places. As a naturalist and environmentalist, Gal
Autor:
Brendan Galvin, Grace Zheng, Robby Moot, Michelle Nguyen, Michelle Tan, Rene Sit, Lionel Berthoin, David DeTomaso, Sofia Kyriazopoulou Panagiotopoulou, Shan Sabri, Jun Feng, Manching Ku, Anzhi Yao, Andrea Liu, Jennifer McDevitt, Matt Drever, Stephen Santoro, Aaron Cooper, Susie Jun, W Nicholas Haining, Tarjei Mikkelsen
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ac8d6c6e7005176d044d0e7b30bd5ec
https://doi.org/10.1136/jitc-2022-sitc2022.0332
https://doi.org/10.1136/jitc-2022-sitc2022.0332
Abstract 5329: High throughput screening strategies in the development of logic gated cell therapies
Autor:
Li Wang, Sofia Kyriazopoulou Panagiotopoulou, Rona Harari-Steinfeld, Dasmanthie De Silva, Michelle Tan, Laura Lim, Angela Boroughs, Cate Sue, Jon Chen, Jamie Thomas, Mary Chua, Ed Yashin, Christine Shieh, Ryan Fong, Sophie Xu, Grace Zheng, Brendan Galvin, Aaron Cooper, Tarjei Mikkelsen, Nicholas Haining
Publikováno v:
Cancer Research. 83:5329-5329
Chimeric antigen receptor T cell (CAR T) therapy has demonstrated unprecedented therapeutic activity in hematologic malignancies. However, generating potent clinical responses against solid tumors remains a challenge for CAR T therapy. As the field s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89fe10645f1da74c515da4449989a8b5
https://doi.org/10.1158/1538-7445.am2023-5329
https://doi.org/10.1158/1538-7445.am2023-5329
Autor:
Vincent Liu, Katalin Sandor, Bence Daniel, Lionel Berthoin, Shan Sabri, Sofia Panagiotopoulou, Yajie Yin, Kamir Hiam-Galvez, Rene Sit, Zi Fan, Brendan Galvin, Omar Khan, Natalie Bezman, Jane Grogan, Brooke Howitt, Grace Zheng, Caleb Lareau, Ansuman Satpathy
Publikováno v:
Cancer Research. 82:1701-1701
Tumor initiation and progression are the result of a close interplay between malignant cells and immune cells. While single-cell genomics has enabled the molecular dissection of the cellular heterogeneity underlying complex cancers, many facets of tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18cf022422aa4bf685bbc2c3cb378b5e
https://doi.org/10.1158/1538-7445.am2022-1701
https://doi.org/10.1158/1538-7445.am2022-1701
Autor:
John Gagnon, Adam J. Litterman, Jason A. Hall, Dina Polyak, Stanley Zhou, Sahil Joshi, Oliver Takacsi-Nagy, Hans Pope, luisa silva, brenal K. Singh, jeffrey M. Granja, david DeTomaso, Edgar Aristil-Lepe, Michelle Tan, Brendan Galvin, Grace X. Zheng, Stephen Santoro, Aaron Cooper, Natalie Bezman, W Nicholas Haining
Publikováno v:
Cancer Research. 82:2830-2830
Cell therapies have shown limited efficacy in solid tumors, in part due to limitations in CAR T cell survival, expansion, and resistance to immunosuppressive pathways operating in the tumor microenvironment (TME). To overcome these hurdles, we screen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f41ea5541a505aded1a4c0eca5f3f38
https://doi.org/10.1158/1538-7445.am2022-2830
https://doi.org/10.1158/1538-7445.am2022-2830
Autor:
Grace X.Y. Zheng, Somya Khare, Brendan Galvin, Robby Moot, Aaron Cooper, Michelle Nguyen, Michelle Tan, Shan Sabri, Audre May, Jun Fung, Anzhi Yao, Andrea Liu, Matt Drever, Steve Santoro, W Nicholas Haining, Tarjei Mikkelsen
Publikováno v:
Cancer Research. 82:2840-2840
T cell therapies for cancer have shown striking clinical efficacy in different tumor settings. Integration of a transgene cassette expressing an antigen receptor into the genome enables T cells to recognize specific tumor antigens. Viral vectors and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ccc8f61abb4c2e3d3288860fe9be2ea
https://doi.org/10.1158/1538-7445.am2022-2840
https://doi.org/10.1158/1538-7445.am2022-2840
Autor:
Sarah B. Kingan, Jonas Korlach, Christine C. Lambert, Brendan Galvin, Haynes Heaton, Juliana Cudini, Mara K. N. Lawniczak, Richard Durbin, Primo Baybayan
Publikováno v:
Genes, Vol 10, Iss 1, p 62 (2019)
Genes
Volume 10
Issue 1
Genes
Volume 10
Issue 1
A high-quality reference genome is a fundamental resource for functional genetics, comparative genomics, and population genomics, and is increasingly important for conservation biology. PacBio Single Molecule, Real-Time (SMRT) sequencing generates lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964ffef929bfb7ff6e6fdbb84c4ce72e
http://www.mdpi.com/2073-4425/10/1/62
http://www.mdpi.com/2073-4425/10/1/62
Autor:
Francesca Meschi, Indira Wu, David Stafford, Andrew Wei Xu, Heather Ordonez, Jill Herschleb, Esty Holt, Tony Makarewicz, Shazia Mahamdallie, Elise Ruark, Josh Delaney, Adam Lowe, Pranav Patel, Stephen R. Williams, Christopher Hindson, Sarah T. Garcia, Nikka Keivanfar, Alvaro Martinez Barrio, Ian T. Fiddes, Keith Bjornson, Sheila Seal, Preyas Shah, Ariel Royall, Claudia Catalanotti, Patrick Marks, Jamie L. Marshall, Daniel G. MacArthur, Rajiv Bharadwaj, Nazneen Rahman, Bill Kengli Lin, Sofia Kyriazopoulou-Panagiotopoulou, Susanna Jett, Adrian Fehr, Haynes Heaton, Christopher J. O'Keefe, Deanna M. Church, Andrew D. Price, Shamoni Maheshwari, Brendan Galvin, Cassandra B. Jabara, Kamila Belhocine, Monkol Lek, Michael Schnall-Levin, Jorge Bernate
Publikováno v:
Genome research. 29(4)
Large-scale population analyses coupled with advances in technology have demonstrated that the human genome is more diverse than originally thought. To date, this diversity has largely been uncovered using short-read whole-genome sequencing. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ac82353829897df4a141dd59feda77
https://pubmed.ncbi.nlm.nih.gov/30894395
https://pubmed.ncbi.nlm.nih.gov/30894395