Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Brendan Elsworth"'
Autor:
Yasaman Rezvani, Caroline D Keroack, Brendan Elsworth, Argenis Arriojas, Marc-Jan Gubbels, Manoj T Duraisingh, Kourosh Zarringhalam
Publikováno v:
PLoS Biology, Vol 20, Iss 9, p e3001816 (2022)
Babesia is a genus of apicomplexan parasites that infect red blood cells in vertebrate hosts. Pathology occurs during rapid replication cycles in the asexual blood stage of infection. Current knowledge of Babesia replication cycle progression and reg
Externí odkaz:
https://doaj.org/article/2ede8dc5c84341669d9a406103994ffd
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 16, Iss , Pp 23-37 (2021)
Plasmodium vivax is the most geographically widespread cause of human malaria and is responsible for the majority of cases outside of the African continent. While great progress has been made towards eliminating human malaria, drug resistant parasite
Externí odkaz:
https://doaj.org/article/564ec85389e24225b05f98171a34cb46
Autor:
Aditya S. Paul, Alexandra Miliu, Joao A. Paulo, Jonathan M. Goldberg, Arianna M. Bonilla, Laurence Berry, Marie Seveno, Catherine Braun-Breton, Aziz L. Kosber, Brendan Elsworth, Jose S. N. Arriola, Maryse Lebrun, Steven P. Gygi, Mauld H. Lamarque, Manoj T. Duraisingh
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Plasmodium protein phosphatase PP1 is essential for the asexual proliferation of malaria parasites. Here the authors show that PP1 regulates egress of parasites from host red blood cells, integrating parasite intrinsic pathways with environmental sig
Externí odkaz:
https://doaj.org/article/7d2715bdc7484f8c88c035dcb70a2f3f
Fussing About Fission: Defining Variety Among Mainstream and Exotic Apicomplexan Cell Division Modes
Autor:
Marc-Jan Gubbels, Caroline D. Keroack, Sriveny Dangoudoubiyam, Hanna L. Worliczek, Aditya S. Paul, Ciara Bauwens, Brendan Elsworth, Klemens Engelberg, Daniel K. Howe, Isabelle Coppens, Manoj T. Duraisingh
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Cellular reproduction defines life, yet our textbook-level understanding of cell division is limited to a small number of model organisms centered around humans. The horizon on cell division variants is expanded here by advancing insights on the fasc
Externí odkaz:
https://doaj.org/article/9052160c60a04e87962310f46bd833ae
Autor:
Mauro F Azevedo, Catherine Q Nie, Brendan Elsworth, Sarah C Charnaud, Paul R Sanders, Brendan S Crabb, Paul R Gilson
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112571 (2014)
Drug discovery is a key part of malaria control and eradication strategies, and could benefit from sensitive and affordable assays to quantify parasite growth and to help identify the targets of potential anti-malarial compounds. Bioluminescence, ach
Externí odkaz:
https://doaj.org/article/e22dc4da0f204f41a369e9e8435d12dc
Autor:
Brendan Elsworth, Caroline Keroack, Yasaman Rezvani, Aditya Paul, Keare Barazorda, Jacob Tennessen, Samantha Sack, Cristina Moreira, Marc-Jan Gubbels, Marvin Meyers, Kourosh Zarringhalam, Manoj Duraisingh
Apicomplexan egress from host cells is fundamental to the spread of infection and is poorly characterized in Babesia spp., parasites of veterinary importance and emerging zoonoses. Through the use of video microscopy, transcriptomics and chemical gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1d1a754d1fe70926f7d5f6c398e0ab9
https://doi.org/10.21203/rs.3.rs-2553721/v1
https://doi.org/10.21203/rs.3.rs-2553721/v1
Autor:
Brendan Elsworth, Caroline D. Keroack, Yasaman Rezvani, Jacob A. Tennessen, Samantha A. Sack, Aditya S. Paul, Cristina K. Moreira, Marc-Jan Gubbels, Kourosh Zarringhalam, Manoj T. Duraisingh
SummaryA unique aspect of apicomplexan biology is the requirement for egress from and invasion into host red blood cells (RBCs). The cellular mechanisms and molecular mediators of RBC egress and invasion remain poorly characterized inBabesiaspp., a g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cec07b27d3e2f6e8bf8ae7ba771627e3
https://doi.org/10.1101/2022.02.17.480550
https://doi.org/10.1101/2022.02.17.480550
Autor:
Yasaman Rezvani, Caroline D Keroack, Brendan Elsworth, Argenis Arriojas, Marc-Jan Gubbels, Manoj T Duraisingh, Kourosh Zarringhalam
Babesiais a genus of Apicomplexan parasites that infect red blood cells in vertebrate hosts. Pathology occurs during rapid replication cycles in the asexual blood-stage of infection. Current knowledge ofBabesiareplication cycle progression and regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03bfd59d741cb09e525dd228e5940b6d
https://doi.org/10.1101/2022.02.11.480160
https://doi.org/10.1101/2022.02.11.480160
Autor:
Brendan Elsworth, Manoj T. Duraisingh
Publikováno v:
Mol Microbiol
Babesia species are tick-borne intracellular parasites that infect the red blood cells of their mammalian host, leading to severe or fatal disease. Babesia spp. infect a wide range of mammalian species and cause a significant economic burden globally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed114fd17c99baa3280e097a08810216
https://europepmc.org/articles/PMC10209834/
https://europepmc.org/articles/PMC10209834/
Fussing About Fission: Defining Variety Among Mainstream and Exotic Apicomplexan Cell Division Modes
Autor:
Caroline D. Keroack, Klemens Engelberg, Daniel K. Howe, Aditya S. Paul, Ciara Bauwens, Isabelle Coppens, Sriveny Dangoudoubiyam, Hanna L. Worliczek, Brendan Elsworth, Manoj T. Duraisingh, Marc-Jan Gubbels
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Cellular reproduction defines life, yet our textbook-level understanding of cell division is limited to a small number of model organisms centered around humans. The horizon on cell division variants is expanded here by advancing insights on the fasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ecd58a4270e8219067b882f7da8b00
https://doi.org/10.3389/fcimb.2020.00269
https://doi.org/10.3389/fcimb.2020.00269