Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Brendan E. Russ"'
Autor:
Brendan E. Russ, Adele Barugahare, Pushkar Dakle, Kirril Tsyganov, Sara Quon, Bingfei Yu, Jasmine Li, Jason K.C. Lee, Moshe Olshansky, Zhaohren He, Paul F. Harrison, Michael See, Simone Nussing, Alison E. Morey, Vibha A. Udupa, Taylah J. Bennett, Axel Kallies, Cornelis Murre, Phillipe Collas, David Powell, Ananda W. Goldrath, Stephen J. Turner
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113301- (2023)
Summary: The differentiation of naive CD8+ T lymphocytes into cytotoxic effector and memory CTL results in large-scale changes in transcriptional and phenotypic profiles. Little is known about how large-scale changes in genome organization underpin t
Externí odkaz:
https://doaj.org/article/a6421ddd15594daaa356a1bca492a4ba
Autor:
Declan L. Turner, Svenja Fritzlar, Sara Sadeghipour, Adele A. Barugahare, Brendan E. Russ, Stephen J. Turner, Rommel A. Mathias
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105168- (2022)
Summary: More than half the world’s population is infected with human cytomegalovirus (HCMV), causing congenital birth defects and impacting the immuno-compromised. Many of the >170 HCMV genes remain uncharacterized, and this gap in knowledge limit
Externí odkaz:
https://doaj.org/article/d3d3183e099843a985101a7dec9804bf
Autor:
Declan L. Turner, Rachel M. Templin, Adele A. Barugahare, Brendan E. Russ, Stephen J. Turner, Georg Ramm, Rommel A. Mathias
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5773 (2022)
Over 50% of the world’s population is infected with Human Cytomegalovirus (HCMV). HCMV is responsible for serious complications in the immuno-compromised and is a leading cause of congenital birth defects. The molecular function of many HCMV protei
Externí odkaz:
https://doaj.org/article/89fc41e3f8924726b5a5c91d901299a0
Autor:
Brendan E. Russ, Moshe Olshansky, Jasmine Li, Michelle L.T. Nguyen, Linden J. Gearing, Thi H.O. Nguyen, Matthew R. Olson, Hayley A. McQuilton, Simone Nüssing, Georges Khoury, Damian F.J. Purcell, Paul J. Hertzog, Sudha Rao, Stephen J. Turner
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3624-3636 (2017)
Summary: Infection triggers large-scale changes in the phenotype and function of T cells that are critical for immune clearance, yet the gene regulatory mechanisms that control these changes are largely unknown. Using ChIP-seq for specific histone po
Externí odkaz:
https://doaj.org/article/caa7cee84b0340d08a22a2756c89adcf
Autor:
Simone Nüssing, Lisa A Miosge, Kah Lee, Moshe Olshansky, Adele Barugahare, Carla M Roots, Yovina Sontani, E Bridie Day, Marios Koutsakos, Katherine Kedzierska, Christopher C Goodnow, Brendan E Russ, Stephen R Daley, Stephen J Turner
Publikováno v:
Immunology & Cell Biology. 100:636-652
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1d10ff753f6791eb3f404bd488efa70
https://doi.org/10.1111/imcb.12566
https://doi.org/10.1111/imcb.12566
Autor:
Brendan E. Russ, Kirril Tsyganov, Sara Quon, Bingfei Yu, Jasmine Li, Jason K. C. Lee, Moshe Olshansky, Zhaohren He, Paul F. Harrison, Adele Barugahare, Michael See, Simone Nussing, Alison E. Morey, Vibha A. Udupa, Taylah .J Bennett, Axel Kallies, Cornelis Murre, Phillipe Collas, David Powell, Ananda W. Goldrath, Stephen J. Turner
SUMMARYThe differentiation of naïve CD8+cytotoxic T lymphocytes (CTLs) into effector and memory states results in large scale changes in transcriptional and phenotypic profiles. Little is known about how large-scale changes in genome organisation re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f595011587c18e27a50ee2f3eb95d75
https://doi.org/10.1101/2023.02.26.530139
https://doi.org/10.1101/2023.02.26.530139
Autor:
Sara Quon, Bingfei Yu, Brendan E. Russ, Kirill Tsyganov, Hongtuyet Nguyen, Clara Toma, Maximilian Heeg, James D. Hocker, J. Justin Milner, Shane Crotty, Matthew E. Pipkin, Stephen J. Turner, Ananda W. Goldrath
Publikováno v:
Immunity. 56:959
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b07a3077aba9052d04dd957315eb67c
https://doi.org/10.1016/j.immuni.2023.03.017
https://doi.org/10.1016/j.immuni.2023.03.017
CD4 + T help promotes influenza virus-specific CD8 + T cell memory by limiting metabolic dysfunction
Autor:
Hayley A McQuilten, Nicole L. La Gruta, Brendan E. Russ, Kylie M. Quinn, Alison Morey, Sanna Wei, Jolie G. Cullen, Stephen J. Turner, Julia E. Prier, Peter C. Doherty, Moshe Olshansky
Publikováno v:
Proceedings of the National Academy of Sciences. 116:4481-4488
There is continued interest in developing novel vaccine strategies that induce establish optimal CD8+ cytotoxic T lymphocyte (CTL) memory for pathogens like the influenza A viruses (IAVs), where the recall of IAV-specific T cell immunity is able to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d3bd5d98887c52ae12387d7218e7822
https://doi.org/10.1073/pnas.1808849116
https://doi.org/10.1073/pnas.1808849116
Autor:
Champa Nataraja, Jacqueline Flynn, Wendy Dankers, Melissa Northcott, Wendy Zhu, Rochelle Sherlock, Taylah J. Bennett, Brendan E. Russ, Iolanda Miceli, Mehnaz Pervin, Akshay D'Cruz, James Harris, Eric F. Morand, Sarah A. Jones
Publikováno v:
Journal of Autoimmunity. 131:102858
Glucocorticoids remain a mainstay of modern medicine due to their ability to broadly suppress immune activation. However, they cause severe adverse effects that warrant urgent development of a safer alternative. The glucocorticoid-induced leucine zip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11febca58b2ff37dcca37d9668178e2
https://doi.org/10.1016/j.jaut.2022.102858
https://doi.org/10.1016/j.jaut.2022.102858
Autor:
Gayle M. Davey, Asolina Braun, Ian A. Parish, Simone Nüssing, Simone L Park, Elise Gressier, David Freestone, Emma Grace Bawden, Teagan Wagner, Tony Tiganis, Annabell Bachem, David E. Gyorki, Moshe Olshansky, Brendan E. Russ, Robyn McConville, Claerwen M. Jones, Sammy Bedoui, David C. Tscharke, Stephen J. Turner, Katharina Hochheiser, Thomas Gebhardt, Marco J Herold, Florian Wiede, Matthias H. Enders
Publikováno v:
The Journal of Experimental Medicine
Hochheiser et al. identify Ptpn2 and KLRG1 as new regulators of CD103+ CD8+ TRM cells in mouse skin. While KLRG1 inhibits TRM formation, genetic Ptpn2 deficiency increases the protective function of TRM cells in infection but aggravates TRM-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d2bf488743d45ea646c91f502f013e
http://europepmc.org/articles/PMC8091133
http://europepmc.org/articles/PMC8091133