Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Brendan D. Hare"'
Autor:
James H. Fox, Melissa N. Boucher, Khalil S. Abedrabbo, Brendan D. Hare, Bethany A. Grimmig, William A. Falls, Sayamwong E. Hammack
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2023)
IntroductionTwo weeks of voluntary exercise in group-housed mice produces a reduction in anxiety-like behaviors across a number of different measures, including a reduction in the anxiety levels typically produced by the anxiogenic serotonergic drug
Externí odkaz:
https://doaj.org/article/d5b40d210e674bb09f367eced780b148
Autor:
Brendan D. Hare, Ryota Shinohara, Rong Jian Liu, Santosh Pothula, Ralph J. DiLeone, Ronald S. Duman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Ketamine exerts fast-acting anti-depressant responses. Here the authors show that dopamine D1 receptor expressing neurons in the medial prefrontal cortex contribute to these antidepressant-like effects in mice.
Externí odkaz:
https://doaj.org/article/2d3337a5795543eab74014329bf3aa23
Autor:
Brendan D. Hare, Ronald S. Duman
Publikováno v:
Chronic Stress, Vol 3 (2019)
Externí odkaz:
https://doaj.org/article/1c7b6db980a14aefa76753ac6fde9371
Publikováno v:
Chronic Stress, Vol 1 (2017)
Stress-associated disorders, including depression and anxiety, impact nearly 20% of individuals in the United States. The social, health, and economic burden imposed by stress-associated disorders requires in depth research efforts to identify suitab
Externí odkaz:
https://doaj.org/article/a58ede43d50d479684408a3a55781c9c
Autor:
Ralph J. DiLeone, Brendan D. Hare
Publikováno v:
Biological psychiatry. 88(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366e5970282701cc8e9b0420ca73d571
https://pubmed.ncbi.nlm.nih.gov/32220499
https://pubmed.ncbi.nlm.nih.gov/32220499
Autor:
Ryota Shinohara, Brendan D. Hare, Rong-Jian Liu, Jin Hua Li, Xiao-Yuan Li, Catharine H. Duman, Ralph J. DiLeone, Ronald S. Duman
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:1-O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24c6bd439ca3d1baf3a471caa92c78f1
https://doi.org/10.1254/jpssuppl.95.0_1-o-011
https://doi.org/10.1254/jpssuppl.95.0_1-o-011
Publikováno v:
Behavioural brain research. 391
Rapastinel, a positive NMDAR modulator, produces rapid-acting and long-lasting antidepressant-like effects; however, unlike ketamine, the abuse potential for rapastinel is minimal. Ketamine has also been shown to induce psychotomimetic/dissociative s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31bcf75b52ab9347a8f7158667836d1f
https://pubmed.ncbi.nlm.nih.gov/32461133
https://pubmed.ncbi.nlm.nih.gov/32461133
Autor:
Ashley E. Lepack, Wenzhu Yue, Matthew J. Girgenti, Eunyoung Bang, Brendan D. Hare, Sriparna Ghosal, Ronald S. Duman
Publikováno v:
Biological Psychiatry. 83:29-37
Background Brain-derived neurotrophic factor (BDNF) plays a key role in the pathophysiology and treatment of depression. Recent clinical studies demonstrate that scopolamine, a nonselective muscarinic acetylcholine receptor antagonist, produces rapid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f1a34bc905bbeaaec7225291f506b9
https://doi.org/10.1016/j.biopsych.2017.06.017
https://doi.org/10.1016/j.biopsych.2017.06.017
Autor:
Brendan D. Hare, Diane M. Jaworski, Tina M. Thornton, William A. Falls, Mercedes Rincon, Angel R. Nebreda, William W. Pendlebury, Sandra Colié
Publikováno v:
Neuropsychopharmacology. 43:393-405
GSK3β plays an essential role in promoting cell death and is emerging as a potential target for neurological diseases. Understanding the mechanisms that control neuronal GSK3β is critical. A ubiquitous mechanism to repress GSK3β involves Akt-media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cfabb937d01a5ec5f4766ab16605774
https://doi.org/10.1038/npp.2017.187
https://doi.org/10.1038/npp.2017.187
Publikováno v:
Current Opinion in Behavioral Sciences. 14:1-8
Psychiatric diseases, notably major depression, are associated with imbalance of excitatory and inhibitory neurotransmission within the prefrontal cortex (PFC) and related limbic brain circuitry. In many cases these illnesses are precipitated or exac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e4975936626672afbfac50a7c976c7
https://doi.org/10.1016/j.cobeha.2016.09.012
https://doi.org/10.1016/j.cobeha.2016.09.012