Effectiveness of SARS-CoV-2 vaccination in patients with rheumatoid arthritis (RA) on DMARDs: as determined by antibody and T cell responses

Autor: Kulveer Mankia, Paul Emery, Lesley-Anne Bissell, Brendan Clarke, Darren Newton, Rebecca L Ross, Laurence Duquenne, Benazir Saleem, Aamir Aslam, Pam Hughes, Diane Corsadden, Clive Carter, Fatima A Nadat, Panji Mulipa, Mark Lobb, Katie Mbara, Ruth Morton, Sophie Dibb, Rahaymin Chowdhury, Alexandra Pike, Vishal Kakkar, Sinisia Savic, Francesco DelGaldo

Publikováno v: RMD Open, Vol 8, Iss 1 (2022)

Externí odkaz: https://doaj.org/article/5dde514756a244ce8e1b853f8feac6a2

Evaluating Evidence of Mechanisms in Medicine : Principles and Procedures

Autor: Veli-Pekka Parkkinen, Christian Wallmann, Michael Wilde, Brendan Clarke, Phyllis Illari, Michael P Kelly, Charles Norell, Federica Russo, Beth Shaw, Jon Williamson

This book is open access under a CC BY license. This book is the first to develop explicit methods for evaluating evidence of mechanisms in the field of medicine. It explains why it can be important to make this evidence explicit, and describes how

C3d‐positive donor‐specific antibodies have a role in pretransplant risk stratification of cross‐match‐positive HLA‐incompatible renal transplantation: United Kingdom multicentre study

Autor: Richard Baker, Christopher H.E. Imray, Louise Howe, Daniel Zehnder, Tracey Rees, Sian Griffin, Robert Higgins, Chloe Martin, Emma Burrows, Adrienne Seitz, Katherine Cullen, Sunil Daga, David Briggs, Adarsh Babu, Daniel A. Mitchell, Natasha A. Khovanova, Nithya Krishnan, Simon Fletcher, Anthony Dorling, Brendan Clarke, Olivia Shaw, Frankie Edwards, Matthew Wellberry-Smith

Publikováno v: Babu, A, Khovanova, N, Shaw, O, Griffin, S, Briggs, D, Krishnan, N S, Fletcher, S, Imray, C, Seitz, A, Baker, R, Wellberry-Smith, M, Clarke, B, Cullen, K, Rees, T, Edwards, F, Burrows, E, Howe, L, Martin, C, Dorling, A, Zehnder, D, Higgins, R M, Mitchell, D A & Daga, S 2020, ' C3d positive donor-specific antibodies have a role in pre-transplant risk stratification of crossmatch positive HLA-incompatible renal transplantation : United Kingdom multicentre study ', Transplant International, vol. 33, no. 9, pp. 1128-1139 . https://doi.org/10.1111/tri.13663

Anti-HLA-antibody characteristics aid to risk-stratify patients and improve long-term renal graft outcomes. Complement activation by donor-specific antibody (DSA) is an important characteristic that may determine renal allograft outcome. There is het

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae58bc814f7b31496a647597e5f82bd
https://doi.org/10.1111/tri.13663

Uncertainty in Drug Discovery: Strategies, Heuristics and Technologies

Autor: Erman Sözüdoğru, Brendan Clarke

Publikováno v: Boston Studies in the Philosophy and History of Science ISBN: 9783030291785

In this chapter we show how pharmacological researchers manage uncertainty when using high-throughput screening (HTS) techniques. HTS allows researchers to rapidly survey the activities of large numbers of chemical compounds against a biological targ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::804cf22a7f6a5c28d0060ab67a45d517
https://doi.org/10.1007/978-3-030-29179-2_7

The nervous system and the anatomy of expression: Sir Charles Bell's anatomical watercolors

Autor: Brendan, Clarke, Charles, Bell

Publikováno v: Progress in brain research. 243

This chapter examines Sir Charles Bell's visual inquiries into the nervous system. Taking as our cue four watercolors currently housed in the UCL Art Collections, we explore Bell's approach to representing the brain and the nervous system by placing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2de2331cf2ea6c65f1c54f82f5333719
https://pubmed.ncbi.nlm.nih.gov/30514521