Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Brendan A C, Harley"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Craniomaxillofacial (CMF) bone injuries present a major surgical challenge and cannot heal naturally due to their large size and complex topography. We are developing a mineralized collagen scaffold that mimics extracellular matrix (ECM) features of
Externí odkaz:
https://doaj.org/article/10562c62c91b41c892d6c27f69543375
Autor:
Jee-Wei Emily Chen, Jan Lumibao, Sarah Leary, Jann N. Sarkaria, Andrew J. Steelman, H. Rex Gaskins, Brendan A. C. Harley
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-15 (2020)
Abstract Background Glioblastoma is the most common and deadly form of primary brain cancer, accounting for more than 13,000 new diagnoses annually in the USA alone. Microglia are the innate immune cells within the central nervous system, acting as a
Externí odkaz:
https://doaj.org/article/4ba57ccb49304f89b69781c60cf3dcd4
Autor:
Mai T. Ngo, Brendan A. C. Harley
Publikováno v:
APL Bioengineering, Vol 5, Iss 2, Pp 020902-020902-19 (2021)
Neurological disorders including traumatic brain injury, stroke, primary and metastatic brain tumors, and neurodegenerative diseases affect millions of people worldwide. Disease progression is accompanied by changes in the brain microenvironment, but
Externí odkaz:
https://doaj.org/article/64071391055f4ca68c27892af049e636
Autor:
Samantha G. Zambuto, Ishita Jain, Kathryn B. H. Clancy, Gregory H. Underhill, Brendan A. C. Harley
Publikováno v:
ACS biomaterials scienceengineering. 8(9)
The endometrium undergoes profound changes in tissue architecture and composition, both during the menstrual cycle as well as in the context of pregnancy. Dynamic remodeling processes of the endometrial extracellular matrix (ECM) are a major element
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::713b4e5239bfd62e3ea628a0f06acc40
https://pubmed.ncbi.nlm.nih.gov/35994527
https://pubmed.ncbi.nlm.nih.gov/35994527
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0212502 (2019)
Hematopoietic stem cells (HSCs) play an important physiological role as regulators of all blood and immune cell populations, and are of clinical importance for bone marrow transplants. Regulating HSC biology in vitro for clinical applications require
Externí odkaz:
https://doaj.org/article/44623c52234d496586aa7772eaafb9ac
Autor:
Jee-Wei Emily, Chen, Sarah, Leary, Victoria, Barnhouse, Jann N, Sarkaria, Brendan A C, Harley
Publikováno v:
Tissue Eng Part A
Glioblastoma (GBM) displays diffusive invasion throughout the brain microenvironment, which is partially responsible for its short median survival rate (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b0079486346b7e1ee59e80523f78f6f
https://pubmed.ncbi.nlm.nih.gov/34435883
https://pubmed.ncbi.nlm.nih.gov/34435883
Autor:
Sara Pedron, Brendan A. C. Harley
Publikováno v:
Frontiers in Materials, Vol 5 (2018)
Externí odkaz:
https://doaj.org/article/4c46b750126648a0971063c5312390a6
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 6 (2018)
Dysregulation of tyrosine kinase receptor (RTK) signaling pathways play important roles in glioblastoma (GBM). However, therapies targeting these signaling pathways have not been successful, partially because of drug resistance. Increasing evidence s
Externí odkaz:
https://doaj.org/article/3ac4f5d3d0ab45399ce01e0100b8003c
Autor:
Ana M. Magariños, Sara Pedron, Marc Creixell, Murat Kilinc, Inna Tabansky, Donald W. Pfaff, Brendan A. C. Harley
Publikováno v:
Frontiers in Materials, Vol 5 (2018)
The study of the behavior of embryonic neurons in controlled in vitro conditions require methodologies that take advantage of advanced tissue engineering approaches to replicate elements of the developing brain extracellular matrix. We report here a
Externí odkaz:
https://doaj.org/article/9d9f95a5e5734ff2926ffe39f2d27a0c
Publikováno v:
Frontiers in Materials, Vol 5 (2018)
The extracellular matrix (ECM) is critical in tumor growth and invasive potential of cancer cells. In glioblastoma tumors, some components of the native brain ECM such as hyaluronic acid (HA) have been suggested as key regulators of processes associa
Externí odkaz:
https://doaj.org/article/cd4fdfd290a8469dbc2689d53373f93a