Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Brendah K. Masisi"'
Autor:
Preyanka Nath, Lutfi H. Alfarsi, Rokaya El-Ansari, Brendah K. Masisi, Busra Erkan, Ali Fakroun, Ian O. Ellis, Emad A. Rakha, Andrew R. Green
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
Breast cancer (BC), characterized by its diverse molecular profiles and clinical outcomes, presents a significant challenge in the development of effective therapeutic strategies. Metabolic reprogramming, a defining characteristic of cancer, has emer
Externí odkaz:
https://doaj.org/article/3997423312ae41fd86c7cd8389a491b3
Autor:
Lutfi H. Alfarsi, Rokaya El Ansari, Madeleine L. Craze, Brendah K. Masisi, Ian O. Ellis, Emad A. Rakha, Andrew R. Green
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background PPFIA1 is an important regulator of cell migration and invasion, regulating focal adhesion signalling and disassembly. PPFIA1 is frequently amplified in breast cancer, and recent functional studies indicate that PPFIA1 is an impor
Externí odkaz:
https://doaj.org/article/f6a4091d88b84618863c892f31ebd515
Autor:
Brendah K. Masisi, Lutfi Alfarsi, Emad A. Rakha, Madeleine L. Craze, Ian O. Ellis, Rokaya El Ansari, Andrew R. Green
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-8 (2020)
BMC Cancer
BMC Cancer
Background PPFIA1 is an important regulator of cell migration and invasion, regulating focal adhesion signalling and disassembly. PPFIA1 is frequently amplified in breast cancer, and recent functional studies indicate that PPFIA1 is an important prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9027e4b7eb857de28040abafe5b6c0
http://link.springer.com/article/10.1186/s12885-020-06939-6
http://link.springer.com/article/10.1186/s12885-020-06939-6
Autor:
Emad A. Rakha, Andrew R. Green, Lutfi Alfarsi, Ian O. Ellis, Madeleine L. Craze, Omar J. Mohammed, Rokaya El Ansari, Brendah K. Masisi
Publikováno v:
Breast Cancer Research and Treatment
Purpose Identification of effective biomarkers for the benefit of endocrine treatment and understanding the molecular pathways that contribute to the development of resistance are of crucial importance to the management of luminal breast cancer. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2e7648b9c6de1efdebcc0e371ac4bf
https://pubmed.ncbi.nlm.nih.gov/34282517
https://pubmed.ncbi.nlm.nih.gov/34282517
Autor:
Lutfi Alfarsi, Emad A. Rakha, Ian O. Ellis, Omar J. Mohammed, Brendah K. Masisi, Ruth M. Parks, Andrew R. Green, Rokaya El Ansari
Publikováno v:
Cancers
Volume 12
Issue 6
Cancers, Vol 12, Iss 1549, p 1549 (2020)
Volume 12
Issue 6
Cancers, Vol 12, Iss 1549, p 1549 (2020)
Endocrine therapy is the mainstay of adjuvant treatment for patients with luminal breast cancer. Despite ongoing advances in endocrine therapy to date, a proportion of patients ultimately develop endocrine resistance, resulting in failure of therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6843d2cc3cf28a9a58677b924e6db508
Autor:
Madeleine L. Craze, Brendah K. Masisi, Lutfi Alfarsi, Rokaya El-Ansari, Ian O. Ellis, Emad A. Rakha, Omar J. Mohammed, Andrew R. Green
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 4
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1407 (2020)
Volume 21
Issue 4
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1407 (2020)
The majority of breast cancers are oestrogen-receptor-positive (ER+) and are subject to endocrine therapy
however, an unpredictable subgroup of patients will develop resistance to endocrine therapy. The SLC7A5/SLC3A2 complex is a major route for
however, an unpredictable subgroup of patients will develop resistance to endocrine therapy. The SLC7A5/SLC3A2 complex is a major route for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b133b41f9b3fa836aac11ad59c99c556
https://pubmed.ncbi.nlm.nih.gov/32093034
https://pubmed.ncbi.nlm.nih.gov/32093034
Autor:
Alfarsi, Lutfi H., Rokaya El Ansari, Craze, Madeleine L., Brendah K. Masisi, Ellis, Ian O., Rakha, Emad A., Green, Andrew R.
Additional file 6: Table 3. Multivariate cox analysis of associations between PPFIA1 mRNA expression and clinicopathological parameters in luminal breast cancer using METABRIC cohort.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a1e406c2b1990afc436d433a3f97af
Autor:
Alfarsi, Lutfi H., Rokaya El Ansari, Craze, Madeleine L., Brendah K. Masisi, Ellis, Ian O., Rakha, Emad A., Green, Andrew R.
Additional file 7: Supplementary Table 4. Correlation of PPFIA1 mRNA expression with the expression of other related genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc42cf7b1e35995e756016c49943bc3
Autor:
Alfarsi, Lutfi H., Rokaya El Ansari, Craze, Madeleine L., Brendah K. Masisi, Ellis, Ian O., Rakha, Emad A., Green, Andrew R.
Additional file 5: Supplementary Table 2. Association of PPFIA1 protein expression and clinicopathological parameters in Nottingham cohort.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7003e94639dc2644ece43a3cfe634a
Autor:
Alfarsi, Lutfi H., Rokaya El Ansari, Craze, Madeleine L., Brendah K. Masisi, Ellis, Ian O., Rakha, Emad A., Green, Andrew R.
Additional file 4: Supplementary Table 1. Clinicopathological characteristics of luminal breast cancer cohorts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bc0ad781a176f560db2d5e220374dd