Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Brenda van Dieren"'
Autor:
Chunyan Wang, Rien van Haperen, Javier Gutiérrez-Álvarez, Wentao Li, Nisreen M. A. Okba, Irina Albulescu, Ivy Widjaja, Brenda van Dieren, Raul Fernandez-Delgado, Isabel Sola, Daniel L. Hurdiss, Olalekan Daramola, Frank Grosveld, Frank J. M. van Kuppeveld, Bart L. Haagmans, Luis Enjuanes, Dubravka Drabek, Berend-Jan Bosch
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Here, the authors report the isolation and characterization of two human monoclonal antibodies (mAbs) from immunized mice with trimeric spike ectodomains of three human betacoronaviruses HCoV-OC43, SARS-CoV and MERSCoV, and show that while exhibiting
Externí odkaz:
https://doaj.org/article/db6da7f5d9bb4e1c916d69bc00d5ab39
Autor:
Nisreen M. A. Okba, Ivy Widjaja, Brenda van Dieren, Andrea Aebischer, Geert van Amerongen, Leon de Waal, Koert J. Stittelaar, Debby Schipper, Byron Martina, Judith M. A. van den Brand, Martin Beer, Berend-Jan Bosch, Bart L. Haagmans
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 1080-1091 (2020)
ABSTRACTMiddle East respiratory syndrome coronavirus (MERS-CoV) is a WHO priority pathogen for which vaccines are urgently needed. Using an immune-focusing approach, we created self-assembling particles multivalently displaying critical regions of th
Externí odkaz:
https://doaj.org/article/eda04ba2d36a4ed8b9a203977286ddba
Autor:
Jordi Rodon, Nisreen M. A. Okba, Nigeer Te, Brenda van Dieren, Berend-Jan Bosch, Albert Bensaid, Joaquim Segalés, Bart L. Haagmans, Júlia Vergara-Alert
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 1593-1603 (2019)
ABSTRACTThe ongoing Middle East respiratory syndrome coronavirus (MERS-CoV) outbreaks pose a worldwide public health threat. Blocking MERS-CoV zoonotic transmission from dromedary camels, the animal reservoir, could potentially reduce the number of p
Externí odkaz:
https://doaj.org/article/c9d80acfca5e4c13999977a662bc76c8
Autor:
Ivy Widjaja, Chunyan Wang, Rien van Haperen, Javier Gutiérrez-Álvarez, Brenda van Dieren, Nisreen M.A. Okba, V. Stalin Raj, Wentao Li, Raul Fernandez-Delgado, Frank Grosveld, Frank J. M. van Kuppeveld, Bart L. Haagmans, Luis Enjuanes, Dubravka Drabek, Berend-Jan Bosch
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 516-530 (2019)
ABSTRACTThe Middle-East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic virus that causes severe and often fatal respiratory disease in humans. Efforts to develop antibody-based therapies have focused on neutralizing antibodies that target
Externí odkaz:
https://doaj.org/article/c5a58e9203e14de48fe994d1b6032c31
Autor:
Shaun Stewart, Floris Fransen, Shane Harvey, Franziska Mortensen, Anita Stam, Rahel Awdew, Arpita Mondal, Christina Stevens, Eric Rovers, Steef Engels, Melissa Rentrop-Boeijen, Linda Hendriks, Brenda van Dieren, Rebecca Buonpane, Therese Visser, Pepijn Schellen, Ashwini Kulkarni, Jonathan Rios-Doria, Jing Zhou, Paul Tacken, Lu Lu, Vanessa Zondag-van der Zande, Cheng-Yen Huang, Renate den Blanken-Smit, John de Kruif, Rinse Klooster, Simon Plyte, Horacio Nastri, Patrick Mayes
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Rien van Haperen, Irina C. Albulescu, Frank Grosveld, Wentao Li, Chunyan Wang, Javier Gutiérrez-Álvarez, Nisreen M.A. Okba, Raúl Fernandez-Delgado, Brenda van Dieren, Frank J. M. van Kuppeveld, Luis Enjuanes, Berend Jan Bosch, Isabel Sola, Daniel L. Hurdiss, Bart L. Haagmans, Olalekan Daramola, Dubravka Drabek, Ivy Widjaja
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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The coronavirus spike glycoprotein, located on the virion surface, is the key mediator of cell entry. As such, it is an attractive target for the development of protective antibodies and vaccines. Here we describe two human monoclonal antibodies, 1.6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb9bb1ea279f9f1ea3bdd7ca2a0663b
https://doi.org/10.1101/2020.10.20.346916
https://doi.org/10.1101/2020.10.20.346916
Autor:
Einar Gran, Espen S. Baekkevold, Frode L. Jahnsen, Guro Reinholt Melum, Finn-Eirik Johansen, Yong-Jun Liu, Brenda Van Dieren, Lorant Farkas, Cecilie Scheel
Publikováno v:
Journal of Allergy and Clinical Immunology. 134:613-621.e7
Background Thymic stromal lymphopoietin (TSLP) controls allergic T H 2 inflammatory responses through induction of distinct activation programs in dendritic cells (DCs). However, knowledge about TSLP receptor expression and functional consequences of