Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Brenda Y Han"'
Autor:
Elizabeth Theusch, Flora Y. Ting, Yuanyuan Qin, Kristen Stevens, Devesh Naidoo, Sarah M. King, Neil V. Yang, Joseph Orr, Brenda Y. Han, Jason G. Cyster, Yii-Der I. Chen, Jerome I. Rotter, Ronald M. Krauss, Marisa W. Medina
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Statins lower circulating low-density lipoprotein cholesterol (LDLC) levels and reduce cardiovascular disease risk. Though highly efficacious in general, there is considerable inter-individual variation in statin efficacy that rem
Externí odkaz:
https://doaj.org/article/86e1c03fd4d3426cb6478f318d675d47
Autor:
Brenda Y Han, Shuang Wu, Chuan-Sheng Foo, Robert M Horton, Craig N Jenne, Susan R Watson, Belinda Whittle, Chris C Goodnow, Jason G Cyster
Publikováno v:
eLife, Vol 3 (2014)
The generation of naïve T lymphocytes is critical for immune function yet the mechanisms governing their maturation remain incompletely understood. We have identified a mouse mutant, bloto, that harbors a hypomorphic mutation in the zinc finger prot
Externí odkaz:
https://doaj.org/article/ddad725609d84747b5161b6b5274b9bf
Autor:
Brenda Y. Han, Michelle K. Y. Seah, Imogen R. Brooks, Delia H. P. Quek, Dominic R. Huxley, Chuan-Sheng Foo, Li Ting Lee, Heike Wollmann, Huili Guo, Daniel M. Messerschmidt, Ernesto Guccione
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
PRDM family members are transcriptional regulators involved in cell identity and fate determination. Here, the authors characterize PRDM10 and show that it functions to ensure global translation efficiency during early embryonic development.
Externí odkaz:
https://doaj.org/article/e7989e77dc6240d282d3dcdcea55b0b3
Autor:
Yaju Wang, Hui Mun Loh, Slim Mzoughi, Michelle K. Y. Seah, Wen Jun Peh, Gernot Wolf, Heike Wollmann, Brenda Y. Han, Esther Sook Miin Wong, Diana Low, Pierre-Alexis Goy, Ernesto Guccione, Ei Leen Leong, Daniel M. Messerschmidt, Todd S. Macfarlan
Publikováno v:
Development (Cambridge, England)
Global epigenetic reprogramming is vital to purge germ cell-specific epigenetic features to establish the totipotent state of the embryo. This process transpires to be carefully regulated and is not an undirected, radical erasure of parental epigenom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af3dec7fd79fa1f67d6506a6bab347c
https://doi.org/10.1242/dev.170266
https://doi.org/10.1242/dev.170266
Publikováno v:
Genes & development, vol 30, iss 13
The complexities of DNA recognition by transcription factors (TFs) with multiple Cys2–His2 zinc fingers (C2H2-ZFs) remain poorly studied. We previously reported a mutation (R1092W) in the C2H2-ZF TF Zfp335 that led to selective loss of binding at a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f653d48f7ca507126e15e06ae08fda1
https://doi.org/10.1101/gad.279406.116
https://doi.org/10.1101/gad.279406.116
Autor:
Christopher C. Goodnow, Belinda Whittle, Robert M. Horton, Craig N. Jenne, Susan R. Watson, Chuan-Sheng Foo, Brenda Y. Han, Shuang Wu, Jason G. Cyster
Publikováno v:
eLife, Vol 3 (2014)
eLife
eLife
The generation of naïve T lymphocytes is critical for immune function yet the mechanisms governing their maturation remain incompletely understood. We have identified a mouse mutant, bloto, that harbors a hypomorphic mutation in the zinc finger prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12691c592380117f49e7da43086ee14e
https://elifesciences.org/articles/03549
https://elifesciences.org/articles/03549
Autor:
Christopher C. Goodnow, Robert M. Horton, Belinda Whittle, Jason G. Cyster, Susan R. Watson, Craig N. Jenne, Shuang Wu, Chuan-Sheng Foo, Brenda Y. Han
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ce2b9fd3c3dc20d4dabc3786102aedc
https://doi.org/10.7554/elife.03549.031
https://doi.org/10.7554/elife.03549.031
