Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Brenda Verhaaf"'
1
Clonal antigen receptor gene PCR products outside the expected size range
Autor: W. Richard Burack, Jacques J. M. van Dongen, Karen Payne, Anton W. Langerak, Chris M. Bacon, Hongxiang Liu, Todd S. Laughlin, Paul G. Rothberg, Betty N. Bandoh, Donald Slate, Qingguo Yan, Luis Figueiredo, Ming-Qing Du, Brenda Verhaaf, A Bench, Penny Wright, Mahlon D. Johnson
Publikováno v: Journal of Hematopathology, 5, 57-67. Springer-Verlag
Polymerase chain reaction (PCR) of the antigen receptor genes has clinical utility in establishing clonality in lymphoproliferations, which is an important correlate of lymphoid neoplasia. The most frequently used procedures for this purpose were dev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6569f2b912118c7be171ad556302500e
https://pure.eur.nl/en/publications/e876c3b4-f35b-4df2-a295-64481e422c40
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2
Human T-cell lines with well-defined T-cell receptor gene rearrangements as controls for the BIOMED-2 multiplex polymerase chain reaction tubes
Autor: Yorick Sandberg, Jeroen G. Noordzij, E. J. Van Gastel-Mol, Brenda Verhaaf, R A F MacLeod, W A Dik, Anthonie Willem Langerak, J. J. M. Van Dongen, Ingrid L. M. Wolvers-Tettero, J de Vos
Publikováno v: Leukemia, 21, 2, pp. 230-7
Leukemia, 21, 230-7
Leukemia, 21(2), 230-237. Nature Publishing Group
Item does not contain fulltext The BIOMED-2 multiplex polymerase chain reaction (PCR) tubes for analysis of immunoglobulin and T-cell receptor (TCR) gene rearrangements have recently been introduced as a reliable and easy tool for clonality diagnosti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ec530224f93520582d74f968973fa9
https://doi.org/10.1038/sj.leu.2404486
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3
Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL
Autor: Christian A. Schmidt, W.-D. Ludwig, Piotr Grabarczyk, S Majunke, José I. Martín-Subero, Grzegorz K. Przybylski, Brenda Verhaaf, W A Dik, Anthonie Willem Langerak, J Wanzeck, Reiner Siebert, Gottfried Dölken, J. J. M. Van Dongen
Publikováno v: Leukemia, 19(2), 201-208. Nature Publishing Group
T-cell acute lymphoblastic leukemia (T-ALL) is associated with chromosomal aberrations characterized by juxtaposition of proto-oncogenes to T-cell receptor gene loci (TCR), resulting in the deregulated transcription of these proto-oncogenes. Here, we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e016783c3f232a94e1d25130a9dc937
https://doi.org/10.1038/sj.leu.2403619
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4
Identification and Characterization of the Interaction between Tuberin and 14-3-3ζ
Autor: Ans M.W. van den Ouweland, Christa de Winter, Miriam A. Goedbloed, Dicky J. J. Halley, Brenda Verhaaf, Anita Jankie, Peter van der Sluijs, Mark Nellist, Arnold J. J. Reuser
Publikováno v: Journal of Biological Chemistry, 277(42), 39417-39424. American Society for Biochemistry and Molecular Biology Inc.
Tuberous sclerosis is caused by mutations to either the TSC1 or TSC2 tumor suppressor gene. The disease is characterized by a broad phenotypic spectrum that includes seizures, mental retardation, renal dysfunction, and dermatological abnormalities. T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee72a4b48fb061028d4400a5158b3e5
https://doi.org/10.1074/jbc.m204802200
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5
PCR-based analysis of rearranged immunoglobulin or T-cell receptor genes by GeneScan analysis or heteroduplex analysis for clonality assessment in lymphoma diagnostics
Autor: Elke, Boone, Brenda, Verhaaf, Anton W, Langerak
Publikováno v: Methods in molecular biology (Clifton, N.J.). 971
The assessment of the presence of clonal lymphoproliferations via polymerase chain reaction (PCR)-based analysis of rearranged immunoglobulin (Ig) or T-cell receptor (TCR) genes is a valuable technique in the diagnosis of suspect lymphoproliferative
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::df273e10cf995f5241ca7d3316581533
https://pubmed.ncbi.nlm.nih.gov/23296958
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6
PCR-Based Analysis of Rearranged Immunoglobulin or T-Cell Receptor Genes by GeneScan Analysis or Heteroduplex Analysis for Clonality Assessment in Lymphoma Diagnostics
Autor: Anton W. Langerak, Elke Boone, Brenda Verhaaf
Publikováno v: Methods in Molecular Biology ISBN: 9781627032681
The assessment of the presence of clonal lymphoproliferations via polymerase chain reaction (PCR)-based analysis of rearranged immunoglobulin (Ig) or T-cell receptor (TCR) genes is a valuable technique in the diagnosis of suspect lymphoproliferative
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f9726f29dfad5402269e8c6ea9a7b34
https://doi.org/10.1007/978-1-62703-269-8_4
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7
Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia
Autor: Johan J. de Rooi, Adolfo A. Ferrando, Pieter Van Vlierberghe, Monique Verstegen, Jean Soulier, Wouter de Laat, Jean Michel Cayuela, Petra Klous, Jules P.P. Meijerink, Jessica Buijs-Gladdines, Irene Homminga, Maartje Vuerhard, François Sigaux, Rob Pieters, Anton W. Langerak, Martin A. Horstmann, Brenda Verhaaf, Anna-Sophia Wiekmeijer, Karin Pike-Overzet, Andrew P. Stubbs, Clarissa Kooi, Frank J. T. Staal, H. Berna Beverloo, Valerie de Haas
Publikováno v: Cancer Cell
Cancer Cell, 19(4), 484-497. Cell Press
Cancer Cell, 19(4), 484-497
Cancer Cell, 19, 484-497. Cell Press
To identify oncogenic pathways in T cell acute lymphoblastic leukemia (T-ALL), we combined expression profiling of 117 pediatric patient samples and detailed molecular-cytogenetic analyses including the Chromosome Conformation Capture on Chip (4C) me
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba8c1029d380a48d2e714d858fa4283
https://doi.org/10.1016/j.ccr.2011.02.008
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10
Different chromosomal breakpoints impact the level of LMO2 expression in T-ALL
Autor: Piotr Grabarczyk, Willem A. Dik, Jacques J.M. van Dongen, Christian A. Schmidt, Grzegorz K. Przybylski, Anton W. Langerak, Vahid Asnafi, Jean Navarro, Brenda Verhaaf, Bertrand Nadel, Elizabeth Macintyre
Publikováno v: Blood
Blood, 2007, 110 (1), pp.388-92. ⟨10.1182/blood-2006-12-064816⟩
Blood, American Society of Hematology, 2007, 110 (1), pp.388-92. ⟨10.1182/blood-2006-12-064816⟩
Blood, 110(1), 388-392. American Society of Hematology
The t(11;14)(p13;q11) is presumed to arise from an erroneous T-cell receptor delta TCRD V(D)J recombination and to result in LMO2 activation. However, the mechanisms underlying this translocation and the resulting LMO2 activation are poorly defined.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0041b79ea01bf26b168e2111c93471e
https://hal.science/hal-00165491
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