Výsledky vyhledávání - "Brenda Souza Monteiro"

Pharmacological effects of a complex α-bisabolol/β-cyclodextrin in a mice arthritis model with involvement of IL-1β, IL-6 and MAPK

Autor: Luana Heimfarth, Marília Matos Rezende, Erik Willyame Menezes Pereira, Fabiolla Rocha Santos Passos, Brenda Souza Monteiro, Tiffany Karoline Barroso Santos, Natália Teles Lima, Isana Carla Leal Souza, Ricardo Luiz Cavalcanti de Albuquerque Junior, Pollyana de Souza Siqueira Lima, Adriano Antunes de Souza Araújo, Lucindo José Quintans Júnior, Bonglee Kim, Henrique D.M. Coutinho, Jullyana de Souza Siqueira Quintans

Publikováno v: Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 151

Inflammatory arthritis is the most prevalent chronic inflammatory disease worldwide. The pathology of the disease is characterized by increased inflammation and oxidative stress, which leads to chronic pain and functional loss in the joints. Conventi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282d07db88310add94d02ac9e74b47d3
https://pubmed.ncbi.nlm.nih.gov/35623175

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Anti-inflammatory and modulatory effects of steroidal saponins and sapogenins on cytokines: A review of pre-clinical research

Autor: Fabiolla Rocha Santos Passos, Jullyana S.S. Quintans, Brenda Souza Monteiro, Lucindo José Quintans Júnior, Heitor G. Araújo-Filho, Adriano Antunes de Souza Araújo, Parimelazhagan Thangaraj, Jackson Roberto Guedes da Silva Almeida, Saravanan Shanmugam

Publikováno v: Phytomedicine : international journal of phytotherapy and phytopharmacology. 96

Saponins are glycosides which, after acid hydrolysis, liberate sugar(s) and an aglycone (sapogenin) which can be triterpenoid or steroidal in nature. Steroidal saponins and sapogenins have attracted significant attention as important natural anti-inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38bafd0d52dff9d947018bfb7921e1a5
https://pubmed.ncbi.nlm.nih.gov/34952766

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Serum glial fibrillary acidic protein is a body fluid biomarker: A valuable prognostic for neurological disease – A systematic review

Autor: Luana, Heimfarth, Fabiolla Rocha Santos, Passos, Brenda Souza, Monteiro, Adriano Antunes de Souza, Araújo, Lucindo José, Quintans Júnior, Jullyana de Souza Siqueira, Quintans

Publikováno v: International Immunopharmacology. 107:108624

Astrocytes are the most abundant cell type in the human central nervous system, and they play an important role in the regulation of neuronal physiology. In neurological disorders, astrocyte disintegration leads to the release of glial fibrillary aci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474cd582985550cd4108bfdf5a3d0c30
https://doi.org/10.1016/j.intimp.2022.108624

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Limonene, a food additive, and its active metabolite perillyl alcohol improve regeneration and attenuate neuropathic pain after peripheral nerve injury: Evidence for IL-1β, TNF-α, GAP, NGF and ERK involvement

Autor: Brenda Souza Monteiro, Luana Heimfarth, Sathiyabama R. Gandhi, Jackson Roberto Guedes da Silva Almeida, Erik Willyame Menezes Pereira, Jullyana S.S. Quintans, Ray S. Almeida, Pollyana S. Siqueira-Lima, Henrique Douglas Melo Coutinho, Natália Martins, Laurent Picot, Fabiolla Rocha Santos Passos, Raphaël Grougnet, Heitor G. Araújo-Filho, Márcio R. V. Santos, Lucindo José Quintans-Júnior

Publikováno v: International Immunopharmacology
International Immunopharmacology, Elsevier, 2020, 86, pp.106766. ⟨10.1016/j.intimp.2020.106766⟩

Background Limonene (LIM) and its main metabolite perillyl alcohol (POH) are ingredients found in food with promising chemical entities due to their pharmacological profile. In this study, we hypothesized that LIM and POH are two molecules capable of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51094f7a6e6d2e1ac90c20b592e1d0c2
https://hal.archives-ouvertes.fr/hal-02946603

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Role of peripheral and central sensitization in the anti-hyperalgesic effect of hecogenin acetate, an acetylated sapogenin, complexed with β-cyclodextrin: Involvement of NFκB and p38 MAPK pathways

Autor: Luana Heimfarth, Rosana S.S. Barreto, Jullyana S.S. Quintans, Jackson Roberto Guedes da Silva Almeida, Yasmim Maria Barbosa Gomes de Carvalho, Adriano Antunes de Souza Araújo, Laurent Picot, Brenda Souza Monteiro, Erik Willyame Menezes Pereira, Lucindo José Quintans-Júnior, Pollyana S. Siqueira-Lima, Henrique Douglas Melo Coutinho, Fabiolla Rocha Santos Passos

Publikováno v: Neuropharmacology
Neuropharmacology, Elsevier, 2021, 186, pp.108395. ⟨10.1016/j.neuropharm.2020.108395⟩

Neuropathic pain develops due to injury to the somatosensory system, affecting the patient's quality of life. In view of the ineffectiveness of the current pharmacotherapy, substances obtained from natural products (NPs) are a promising alternative.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6adc034db6729c6d6e0661f1ab23be1
https://pubmed.ncbi.nlm.nih.gov/33516738

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Oxidative stress and inflammatory markers in patients with COVID-19: Potential role of RAGE, HMGB1, GFAP and COX-2 in disease severity

Autor: Fabiolla Rocha Santos, Passos, Luana, Heimfarth, Brenda Souza, Monteiro, Cristiane Bani, Corrêa, Tatiana Rodrigues de, Moura, Adriano Antunes de Souza, Araújo, Paulo Ricardo, Martins-Filho, Lucindo José, Quintans-Júnior, Jullyana de Souza Siqueira, Quintans

Publikováno v: International Immunopharmacology

Background SARS-CoV-2 infection can lead to the abnormal induction of cytokines and a dysregulated hyperinflammatory state that is implicated in disease severity and risk of death. There are several molecules present in blood associated with immune c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723ed2be74ba4105abf2f0d40a6f0ba8
https://doi.org/10.1016/j.intimp.2021.108502

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HPLC-DAD-UV analysis, anti-inflammatory and anti-neuropathic effects of methanolic extract of Sideritis bilgeriana (lamiaceae) by NF-κB, TNF-α, IL-1β and IL-6 involvement

Autor: Yuri Mangueira do Nascimento, Adriano Antunes de Souza Araújo, Irwin Rose Alencar de Menezes, Lucindo José Quintans-Júnior, Abdurrahman Aktumsek, Marcelo Cavalcante Duarte, Brenda Souza Monteiro, Luana Heimfarth, Sathiyabama R. Gandhi, Ramazan Ceylan, Fabiolla Rocha Santos Passos, Jullyana S.S. Quintans, Henrique Douglas Melo Coutinho, Bruno dos Santos Lima, Mariana R.M. Cavalcanti, Gokhan Zengin

Publikováno v: Journal of Ethnopharmacology. 265:113338

Medicinal plants remain an invaluable source for therapeutics of diseases that affect humanity. Sideritis bilgeriana (Lamiaceae) is medicinal plant used in Turkey folk medicine to reduce inflammation and pain, but few studies scientific corroborates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a0778cc7b6786ad953185fbfc3c42f3
https://doi.org/10.1016/j.jep.2020.113338

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Dereplication and quantification of the ethanol extract of Miconia albicans (Melastomaceae) by HPLC-DAD-ESI-/MS/MS, and assessment of its anti-hyperalgesic and anti-inflammatory profiles in a mice arthritis-like model: Evidence for involvement of TNF-α, IL-1β and IL-6

Autor: Marcelo Sobral da Silva, Fabiolla Rocha Santos Passos, Josean Fechine Tavares, Gokhan Zengin, Erik Willyame Menezes Pereira, Marcelo Cavalcante Duarte, Katielen Silvana dos Santos, Irwin Rose Alencar de Menezes, Lucindo José Quintans-Júnior, Brenda Souza Monteiro, Sathiyabama R. Gandhi, Lucas Silva Abreu, Jullyana S.S. Quintans, Yuri Mangueira do Nascimento, Henrique Douglas Melo Coutinho, Ádley Antonini Neves de Lima, Luana Heimfarth

Publikováno v: Journal of Ethnopharmacology. 258:112938

Miconia albicans (Sw) Triana (Melastomataceae), a medicinal plant widely used by practitioners of folk medicine in the northeast of Brazil, has been used to treat chronic inflammatory disorders, such as rheumatoid arthritis (RA) and other joint condi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac1a7c96333dfccac57ff82801e12cf
https://doi.org/10.1016/j.jep.2020.112938

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