Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Brenda Schoffstall"'
Autor:
Yun Shi, Linda Stroud, Vincent A. LaBarbera, Quinton R. Sparrow, Fang Wang, Lauren E. Kessler, Brenda Schoffstall, Prescott B. Chase
Publikováno v:
Biophysical Journal. 121:37a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f320a72aef9adb2389ebf30c04ac8473
https://doi.org/10.1016/j.bpj.2021.11.2536
https://doi.org/10.1016/j.bpj.2021.11.2536
Publikováno v:
Archives of Biochemistry and Biophysics. :11-20
Investigations of cardiomyopathy mutations in Ca(2+) regulatory proteins troponin and tropomyosin provide crucial information about cardiac disease mechanisms, and also provide insights into functional domains in the affected polypeptides. Hypertroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bcb69ecfb59dcdeec124640175ae35a
https://doi.org/10.1016/j.abb.2013.12.021
https://doi.org/10.1016/j.abb.2013.12.021
Publikováno v:
BioResearch Open Access
BioResearch Open Access, Vol 1, Iss 2, Pp 88-91 (2012)
BioResearch Open Access, Vol 1, Iss 2, Pp 88-91 (2012)
Although human cardiomyocytes (CMs) are capable of some cell division, this response is neither sufficient to repair damaged cardiac tissue nor efficient to compensate for pathological stress. Danio rerio (zebrafish) CMs have been shown to have high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5408d69d027b0d2403313a6165b7a7
https://doi.org/10.1089/biores.2012.0201
https://doi.org/10.1089/biores.2012.0201
Autor:
Alyson T. Barnes, Nicolas M. Brunet, Victor F. Miller, P. Bryant Chase, Dianne W. Taylor, Lori A. McFadden, Brenda Schoffstall, Fang Wang, Margaret Seavy, Lisa A. Compton, Shanedah T. Williams, Rani Dhanarajan
Publikováno v:
The Journal of Physiology. 577:935-944
Myosin heavy chain (MHC) isoforms in vertebrate striated muscles are distinguished functionally by differences in chemomechanical kinetics. These kinetic differences may influence the cross-bridge-dependent co-operativity of thin filament Ca2+ activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce53ad294bc3aac9ed7735f28cb393c9
https://doi.org/10.1113/jphysiol.2006.120105
https://doi.org/10.1113/jphysiol.2006.120105
Publikováno v:
Florida Entomologist. 96:679-681
SUMMARY We reared a lab culture of Leiobunum sp. harvestmen adults in 2011, and captured several unique photo images of developing eggs and a hatchling. These images are perhaps the first to be recorded for this genus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbec3900b9b3b97130a307c7e136d26e
https://doi.org/10.1653/024.096.0246
https://doi.org/10.1653/024.096.0246
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 312:12-18
The immunosuppressant drug rapamycin attenuates the effects of many cardiac hypertrophy stimuli both in vitro and in vivo. Although rapamycin's inhibition of mammalian target of rapamycin and its associated signaling pathways is well established, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cba739131cc5d226d7620bba2cb2619
https://doi.org/10.1124/jpet.104.073445
https://doi.org/10.1124/jpet.104.073445
Autor:
Vincent A. LaBarbera, Lauren Herring, P.B. Chase, Aya K. Takeda, Brenda Schoffstall, Sara C. Heshmati, Nancy L. Meyer, Brittany H. Kraft, Belinda J. Gavino, Vanessa Inchausti, Danamarie Moonoo, Nicolas M. Brunet
Publikováno v:
DNA and cell biology. 30(9)
Ca(2+) signaling in striated muscle cells is critically dependent upon thin filament proteins tropomyosin (Tm) and troponin (Tn) to regulate mechanical output. Using in vitro measurements of contractility, we demonstrate that even in the absence of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dfe30d10c0098ab37169c0eac351340
https://pubmed.ncbi.nlm.nih.gov/21438758
https://pubmed.ncbi.nlm.nih.gov/21438758
Autor:
P. Bryant Chase, Vincent A. LaBarbera, Vanessa Inchausti, Brenda Schoffstall, Nancy L. Meyer, Nicolas M. Brunet, Danamarie Moonoo
Publikováno v:
Biophysical Journal. 98(3)
Ca2+ regulation of cardiac muscle contraction is dependent upon regulation by tropomyosin (Tm) and troponin (Tn); the extreme C-terminus of the inhibitory subunit of Troponin (cTnI) binds to actin at low [Ca2+] and is presumed to hold Tm in a closed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81310290802e22e8a196adc3799991e
Autor:
P. Bryant Chase, Brenda Schoffstall
Although ATP is the physiological substrate for cardiac contraction, cardiac contractility is significantly enhanced in vitro when only 10% of ATP substrate is replaced with 2'-deoxy-ATP (dATP). To determine the functional effects of increased intrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc212a4d744a9f3870a142567a6773d
https://europepmc.org/articles/PMC4905737/
https://europepmc.org/articles/PMC4905737/
Publikováno v:
Biophysical Journal. 106:770a
Investigations of cardiomyopathy mutations in Ca2+ regulatory proteins troponin and tropomyosin provide crucial information about cardiac disease mechanisms, and provide insights into functional domains in the affected polypeptides. Hypertrophic card
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9dac5c92fb75ad093f0823e34fb2ff
https://doi.org/10.1016/j.bpj.2013.11.4228
https://doi.org/10.1016/j.bpj.2013.11.4228