Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Brenda R. Carrillo-Conde"'
Autor:
Nicola L. B. Pohl, Balaji Narasimhan, Yashdeep Phanse, Brenda R. Carrillo-Conde, Michael J. Wannemuehler, Scott Broderick, Krishna Rajan, Rajarshi Roychoudhury, Bryan H. Bellaire, Amanda E. Ramer-Tait
Publikováno v:
Journal of Biomedical Materials Research Part A. 105:2762-2771
Rational design of adjuvants and delivery systems will promote development of next-generation vaccines to control emerging and re-emerging diseases. To accomplish this, understanding the immune-enhancing properties of new adjuvants relative to those
Autor:
Yashdeep Phanse, Brenda R. Carrillo-Conde, Balaji Narasihan, Bryan H. Bellaire, Paul Lueth, Amanda E. Ramer-Tait, Michael J. Wannemuehler
Publikováno v:
Journal of biomedical nanotechnology. 12(7)
Polyanhydride nanoparticles have emerged as a versatile delivery platform, due to their ability to encapsulate diverse drugs, immunogens, antibodies, and proteins. However, mechanistic studies on the effects of particle chemistry interactions with im
Autor:
Steven J. Seiler, Michael J. Wannemuehler, Amanda E. Ramer-Tait, Ross J. Darling, Balaji Narasimhan, Brenda R. Carrillo-Conde
Publikováno v:
Chemical Engineering Science. 125:98-107
Passive administration of antibodies (e.g., anti-serum or monoclonal antibodies) can be successfully used as treatments for infectious agents (e.g., human cytomegalovirus, HIV), chronic inflammation (e.g., anti-TNF), cancer (e.g., anti-HER2, anti-VEG
Autor:
Yashdeep, Phanse, Brenda R, Carrillo-Conde, Amanda E, Ramer-Tait, Rajarshi, Roychoudhury, Scott, Broderick, Nicola, Pohl, Krishna, Rajan, Balaji, Narasimhan, Michael J, Wannemuehler, Bryan H, Bellaire
Publikováno v:
Journal of biomedical materials research. Part A. 105(10)
Rational design of adjuvants and delivery systems will promote development of next-generation vaccines to control emerging and re-emerging diseases. To accomplish this, understanding the immune-enhancing properties of new adjuvants relative to those
Publikováno v:
Biomacromolecules. 15:2725-2734
Oral drug delivery is a route of choice for vaccine administration because of its noninvasive nature and thus efforts have focused on efficient delivery of vaccine antigens to mucosal sites. An effective oral vaccine delivery system must protect the
Autor:
Vijaya B. Joshi, Aliasger K. Salem, Brenda R. Carrillo-Conde, Balaji Narasimhan, Sean M. Geary
Publikováno v:
Acta Biomaterialia. 9:5583-5589
Delivery of vaccine antigens with an appropriate adjuvant can trigger potential immune responses against cancer leading to reduced tumor growth and improved survival. In this study, various formulations of a bioerodible amphiphilic polyanhydride copo
Autor:
Lynn Pruisner, Amanda E. Ramer-Tait, Lucas Huntimer, Kathleen A. Ross, Balaji Narasimhan, Chong Wang, Brenda R. Carrillo-Conde, Michael J. Wannemuehler, Jennifer H. Wilson Welder
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. :91-98
Microparticle adjuvants based on biodegradable polyanhydrides were used to provide controlled delivery of a model antigen, ovalbumin (Ova), to mice. Ova was encapsulated into two different polyanhydride microparticle formulations to evaluate the infl
Autor:
Amanda E. Ramer-Tait, Brenda R. Carrillo-Conde, Michael J. Wannemuehler, Nicola L. B. Pohl, Yashdeep Phanse, Ana Vianey Chavez-Santoscoy, Balaji Narasimhan, Eun-Ho Song, Bryan H. Bellaire
Publikováno v:
Molecular Pharmaceutics. 8:1877-1886
Targeting pathogen recognition receptors on dendritic cells (DCs) offers the advantage of triggering specific signaling pathways to induce a tailored and robust immune response. In this work, we describe a novel approach to targeted antigen delivery
Publikováno v:
Industrialengineering chemistry research. 54(42)
Oral administration of monoclonal antibodies (mAbs) may enable the localized treatment of infections or other conditions in the gastrointestinal tract (GI) as well as systemic diseases. As with the development of oral protein biotherapeutics, one of
Autor:
Krishna Rajan, Robert Barry Mandell, Michael J. Wannemuehler, Yashdeep Phanse, Chang Sun Kong, Brenda R. Carrillo-Conde, Ramon Flick, Scott Broderick, Balaji Narasimhan, Amanda E. Ramer-Tait
Publikováno v:
Scientific Reports
Innovative vaccine platforms are needed to develop effective countermeasures against emerging and re-emerging diseases. These platforms should direct antigen internalization by antigen presenting cells and promote immunogenic responses. This work des