Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Brenda M. Gannon"'
Publikováno v:
J Exp Anal Behav
Polysubstance use makes up a majority of drug use, yet relatively few studies investigate the abuse-related effects of drug mixtures. Dose-addition analyses provide a rigorous and quantitative method to determine the nature of the interaction (i.e.,
Autor:
Lauren Russell, Christy M Simecka, Brenda M. Gannon, William E. Fantegrossi, Mildred M Randolph, William S. Hyatt
Publikováno v:
J Am Assoc Lab Anim Sci
Drug developers worldwide assess compound safety and efficacy using measures that include mouse core temperature and locomotor activity. Subtle differences in animal housing conditions between institutions can alter these values, impacting scientific
Publikováno v:
Psychopharmacology. 238:1183-1192
Oxycodone is one of the most commonly prescribed and most frequently abused opioid analgesics, yet little is known regarding individual vulnerabilities to oxycodone abuse. The synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV) has been shown t
Autor:
Martilias S Farrell, John D McCorvy, Xi-Ping Huang, Daniel J Urban, Kate L White, Patrick M Giguere, Allison K Doak, Alison I Bernstein, Kristen A Stout, Su Mi Park, Ramona M Rodriguiz, Bradley W Gray, William S Hyatt, Andrew P Norwood, Kevin A Webster, Brenda M Gannon, Gary W Miller, Joseph H Porter, Brian K Shoichet, William E Fantegrossi, William C Wetsel, Bryan L Roth
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150602 (2016)
RATIONALE:The sacred lotus (Nelumbo nucifera) contains many phytochemicals and has a history of human use. To determine which compounds may be responsible for reported psychotropic effects, we used in silico predictions of the identified phytochemica
Externí odkaz:
https://doaj.org/article/6d67de2b55b746cc9335cb74037f20c1
Autor:
Julian, Maier, Laurin, Rauter, Deborah, Rudin, Marco, Niello, Marion, Holy, Diethart, Schmid, Joseph, Wilson, Bruce E, Blough, Brenda M, Gannon, Kevin S, Murnane, Harald H, Sitte
Publikováno v:
Neuropharmacology. 190
While classical cathinones, such as methcathinone, have been shown to be monoamine releasing agents at human monoamine transporters, the subgroup of α-pyrrolidinophenones has thus far solely been characterized as monoamine transporter reuptake inhib
Publikováno v:
Psychopharmacology. 238(4)
Oxycodone is one of the most commonly prescribed and most frequently abused opioid analgesics, yet little is known regarding individual vulnerabilities to oxycodone abuse. The synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV) has been shown t
Publikováno v:
CNSneurological disorders drug targets. 21(1)
Alcohol-use disorder (AUD) remains a major public health concern. In recent years, there has been a heightened interest in components of the endocannabinoid system for the treatment of AUD. Cannabinoid type 1 (CB1) receptors have been shown to modula
Publikováno v:
Psychopharmacology. 236:1031-1041
RATIONALE: “Bath salts” preparations often contain combinations of synthetic cathinones (e.g., 3,4methylenedioxymethcathinone [methylone], 3,4-methylenedioxypyrovalerone [MDPV]) and caffeine, and evidence suggests that mixtures of synthetic cathi
Autor:
Cristian Jimenez-Morigosa, Agnieszka Sulima, Gregory T. Collins, Donna Walther, Brenda M. Gannon, Kenner C. Rice, Michael H. Baumann
Publikováno v:
Neuropsychopharmacology. 43:2399-2407
Synthetic cathinones are common constituents of abused “bath salts” preparations and represent a large family of structurally related compounds that function as cocaine-like inhibitors or amphetamine-like substrates of dopamine (DAT), norepinephr
Autor:
Kenner C. Rice, Kayla I. Galindo, Gregory T. Collins, Brenda M. Gannon, Agnieszka Sulima, Melson P. Mesmin
Publikováno v:
Neuropharmacology. 134:28-35
“Bath salts” preparations contain synthetic cathinones which interact with monoamine transporters and function as either monoamine uptake inhibitors or releasers. 3,4-Methylenedioxypyrovalerone (MDPV), 3,4-methylenedioxymethcathinone (methylone),