Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Brenda M Ogle"'
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136199 (2015)
The plasticity and immunomodulatory capacity of mesenchymal stem cells (MSCs) have spurred clinical use in recent years. However, clinical outcomes vary and many ascribe inconsistency to the tissue source of MSCs. Yet unconsidered is the extent of he
Externí odkaz:
https://doaj.org/article/b534af6950b24d088f48c95517376c7f
Autor:
Jayne M Squirrell, Jimmy J Fong, Carlos A Ariza, Amber Mael, Kassondra Meyer, Nirupama K Shevde, Avtar Roopra, Gary E Lyons, Timothy J Kamp, Kevin W Eliceiri, Brenda M Ogle
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43708 (2012)
The therapeutic potential of stem cells is limited by the non-uniformity of their phenotypic state. Thus it would be advantageous to noninvasively monitor stem cell status. Driven by this challenge, we employed multidimensional multiphoton microscopy
Externí odkaz:
https://doaj.org/article/36ef4ca9d3c44326a4d66fe5b8c8a324
Autor:
Jinsha Koroth, Casey Chitwood, Ramya Kumar, Wei-Han Lin, Benjamin T. Reves, Todd Boyce, Theresa M. Reineke, Arin M. Ellingson, Casey P. Johnson, Laura S. Stone, Kimberly C. Chaffin, Narendra K. Simha, Brenda M. Ogle, Elizabeth W. Bradley
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Intervertebral disc (IVD) degeneration is a common pathological condition associated with low back pain. Recent evidence suggests that mesenchymal signaling cells (MSCs) promote IVD regeneration, but underlying mechanisms remain poorly defined. One p
Externí odkaz:
https://doaj.org/article/0cc96a196361486083562c995cf81dc1
Autor:
Martha E. Floy, Fathima Shabnam, Sophie E. Givens, Vaidehi A. Patil, Yunfeng Ding, Grace Li, Sushmita Roy, Amish N. Raval, Eric G. Schmuck, Kristyn S. Masters, Brenda M. Ogle, Sean P. Palecek
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Introduction: Fibroblasts are mesenchymal cells that predominantly produce and maintain the extracellular matrix (ECM) and are critical mediators of injury response. In the heart, valve interstitial cells (VICs) are a population of fibroblasts respon
Externí odkaz:
https://doaj.org/article/a537963323944b3b94074d536215d926
Autor:
Jinsha Koroth, Erick O. Buko, Rebecca Abbott, Casey P. Johnson, Brenda M. Ogle, Laura S. Stone, Arin M. Ellingson, Elizabeth W. Bradley
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1367 (2023)
The intervertebral disc (IVD) aids in motion and acts to absorb energy transmitted to the spine. With little inherent regenerative capacity, degeneration of the intervertebral disc results in intervertebral disc disease, which contributes to low back
Externí odkaz:
https://doaj.org/article/a56a827da3b543629e3b5a9577906b37
Autor:
Wei-Han Lin, Zhijie Zhu, Vasanth Ravikumar, Vinod Sharma, Elena G. Tolkacheva, Michael C. McAlpine, Brenda M. Ogle
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14444 (2022)
Bionic-engineered tissues have been proposed for testing the performance of cardiovascular medical devices and predicting clinical outcomes ex vivo. Progress has been made in the development of compliant electronics that are capable of monitoring tre
Externí odkaz:
https://doaj.org/article/baad79d10a0b478198a15e1ab27c2d65
Autor:
Bhairab N. Singh, Dogacan Yucel, Bayardo I. Garay, Elena G. Tolkacheva, Michael Kyba, Rita C.R. Perlingeiro, Jop H. van Berlo, Brenda M. Ogle
Publikováno v:
Circulation Research. 132:519-540
During cardiac development and morphogenesis, cardiac progenitor cells differentiate into cardiomyocytes that expand in number and size to generate the fully formed heart. Much is known about the factors that regulate initial differentiation of cardi
Autor:
An Xie, Gyeoung-Jin Kang, Eun Ji Kim, Feng Feng, Sophie E Givens, Brenda M Ogle, Samuel C Dudley
Publikováno v:
PNAS Nexus.
Automaticity involves Ca2+ handling at the cell membrane and sarcoplasmic reticulum (SR). Abnormal or acquired automaticity is thought to initiate ventricular arrhythmias associated with myocardial ischemia. Ca2+ flux from mitochondria can influence
Autor:
Mikayla L. Hall, Sophie Givens, Natasha Santosh, Michelina Iacovino, Michael Kyba, Brenda M. Ogle
Publikováno v:
Stem Cell Reports. 17:569-583
The extracellular matrix (ECM) provides essential cues to promote endothelial specification during tissue development in vivo; correspondingly, ECM is considered essential for endothelial differentiation outside of the body. However, systematic studi
Autor:
Casey A. Chitwood, Elizabeth D. Shih, Omid Amili, Anthony S. Larson, Brenda M. Ogle, Patrick W. Alford, Andrew W. Grande
Publikováno v:
Neurosurgery clinics of North America. 33(4)
Predicting rupture risk in intracranial aneurysms is among one of the most critical questions in vascular surgery. The processes that govern an aneurysm growth are multifaceted and complex, but may be summarized into three components: hemodynamics, b