Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Brenda L. Petrella"'
Publikováno v:
Cancer Medicine
Effective treatment of metastatic renal cell carcinoma (RCC) remains a major medical concern, as these tumors are refractory to standard therapies and prognosis is poor. Although molecularly targeted therapies have shown some promise in the treatment
Autor:
Abigail M. Fellows, Peter M. Morganelli, Ralph C. Nichols, Brenda L. Petrella, R. Brooks Robey, Lihui Zhong, Roy A. Fava, Mary E. Griffin, Fatemeh P. Parvin-Nejad
Publikováno v:
Molecular Biology of the Cell
Vascular endothelial growth factor (VEGF) expression is regulated by sequence elements in the 3′ UTR of VEGF mRNA. AUF1/hnRNP D suppresses VEGF 3′ UTR–dependent expression. Peptides with arginine–glycine–glycine motifs derived from AUF1 als
Autor:
Brenda L. Petrella
Publikováno v:
Current Protocols in Microbiology
This unit is an overview of biosafety compliance and oversight in the United States. Specific attention is given to the oversight of the Institutional Biosafety Committee (IBC) and how the purview of the IBC may overlap with other local committees, s
Publikováno v:
Cancer letters. 325(2)
Cytokines present in the tumor microenvironment can promote the invasiveness and metastatic potential of cancer cells. We therefore investigated the effects of interleukin-1 beta (IL-1B) and transforming growth factor beta-3 (TGFB3) on the non-small
Autor:
Mukundan Attur, Steven B. Abramson, Dana E. Walkenhorst, Martina Gogarty, Brenda L. Petrella, Aisling Smyth, Kevin McMahon, Kimberlee S. Mix, Ursula Fearon, Douglas J. Veale, Jason P. McMorrow, Evelyn P. Murphy
Publikováno v:
Arthritis and rheumatism. 64(7)
Objective To address the role of the nuclear receptor 4A (NR4A) family of orphan nuclear receptors in synoviocyte transformation, hyperplasia, and regulation of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in m
Publikováno v:
Journal of cellular physiology. 226(12)
CCAAT-enhancer-binding protein beta (CEBPB) is a pluripotent transcription factor that controls inflammation, proliferation, and differentiation. We recently reported a role for CEBPB during matrix metalloproteinase (MMP) gene expression, but the mec
Despite recent advances in cancer therapies, metastatic renal cell carcinoma (RCC) remains difficult to treat. Most RCCs result from inactivation of the von Hippel Lindau (VHL) tumor suppressor, leading to stable expression of Hypoxia-Inducible Facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a715e62aad5bf532d1f21ce2629ea1
https://europepmc.org/articles/PMC2761525/
https://europepmc.org/articles/PMC2761525/
Autor:
Brenda L, Petrella
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 511
Matrix invasion by a tumor cell requires the degradation of components in the extracellular matrix (ECM) as one of the initial steps in the metastatic process. Tumors cells achieve ECM invasion primarily through the overexpression of matrix metallopr
Autor:
Brenda L. Petrella
Publikováno v:
Methods in Molecular Biology ISBN: 9781934115145
Matrix invasion by a tumor cell requires the degradation of components in the extracellular matrix (ECM) as one of the initial steps in the metastatic process. Tumors cells achieve ECM invasion primarily through the overexpression of matrix metallopr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bc06d69c714b793d3b1f58be8afd6ff
https://doi.org/10.1007/978-1-59745-447-6_3
https://doi.org/10.1007/978-1-59745-447-6_3