Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Brenda L Coomber"'
Autor:
Andi Flory, Kristina M Kruglyak, John A Tynan, Lisa M McLennan, Jill M Rafalko, Patrick Christian Fiaux, Gilberto E Hernandez, Francesco Marass, Prachi Nakashe, Carlos A Ruiz-Perez, Donna M Fath, Thuy Jennings, Rita Motalli-Pepio, Kate Wotrang, Angela L McCleary-Wheeler, Susan Lana, Brenda Phillips, Brian K Flesner, Nicole F Leibman, Tracy LaDue, Chelsea D Tripp, Brenda L Coomber, J Paul Woods, Mairin Miller, Sean W Aiken, Amber Wolf-Ringwall, Antonella Borgatti, Kathleen Kraska, Christopher B Thomson, Alane Kosanovich Cahalane, Rebecca L Murray, William C Kisseberth, Maria A Camps-Palau, Franck Floch, Claire Beaudu-Lange, Aurélia Klajer-Peres, Olivier Keravel, Luc-André Fribourg-Blanc, Pascale Chicha Mazetier, Angelo Marco, Molly B McLeod, Erin Portillo, Terry S Clark, Scott Judd, C Kirk Feinberg, Marie Benitez, Candace Runyan, Lindsey Hackett, Scott Lafey, Danielle Richardson, Sarah Vineyard, Mary Tefend Campbell, Nilesh Dharajiya, Taylor J Jensen, Dirk van den Boom, Luis A Diaz, Daniel S Grosu, Arthur Polk, Kalle Marsal, Susan Cho Hicks, Katherine M Lytle, Lauren Holtvoigt, Jason Chibuk, Ilya Chorny, Dana W Y Tsui
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0266623 (2022)
Cancer is the leading cause of death in dogs, yet there are no established screening paradigms for early detection. Liquid biopsy methods that interrogate cancer-derived genomic alterations in cell-free DNA in blood are being adopted for multi-cancer
Externí odkaz:
https://doaj.org/article/941919387dec4012ae30e0d3a5f983c6
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103243 (2014)
DNA hypomethylation is an important epigenetic modification found to occur in many different cancer types, leading to the upregulation of previously silenced genes and loss of genomic stability. We previously demonstrated that hypoxia and hypoglycaem
Externí odkaz:
https://doaj.org/article/7067fdb60df84cb98aebdd1413fb9a45
Autor:
Sirin A I Adham, Hasina Al Rawahi, Sumaya Habib, Mansour S Al Moundhri, Alicia Viloria-Petit, Brenda L Coomber
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113103 (2014)
Breast cancer (BC) arises commonly in women with metabolic dysfunction. The underlying mechanism by which glycemic load can exert its action on tumor metastasis is under investigated. In this study we showed that glycemic microenvironment alters the
Externí odkaz:
https://doaj.org/article/3f1a27c887dd4fb39f5f05be72f3412d
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53385 (2012)
The purpose of these experiments was to evaluate the expression of endothelial markers, such as Tie2 and VEGFR2 in endothelial cells derived from blood mononuclear endothelial progenitor cells. Bovine mononuclear cells were isolated using separation
Externí odkaz:
https://doaj.org/article/624a04647e0548c5921797a4f0c1bd4a
Autor:
Andi Flory, Lisa McLennan, Betsy Peet, Marissa Kroll, Deirdre Stuart, Devon Brown, Kathy Stuebner, Brenda Phillips, Brenda L. Coomber, J. Paul Woods, Mairin Miller, Chelsea D. Tripp, Amber Wolf‐Ringwall, Kristina M. Kruglyak, Angela L. McCleary‐Wheeler, Ashley Phelps‐Dunn, Lilian K. Wong, Chelsea D. Warren, Gina Brandstetter, Michelle C. Rosentel, Lauren R. DiMarzio, Allison L. O'Kell, Todd A. Cohen, Daniel S. Grosu, Jason Chibuk, Dana W. Y. Tsui, Ilya Chorny, Jill M. Rafalko
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 1, Pp 258-267 (2023)
Abstract Background Guidelines‐driven screening protocols for early cancer detection in dogs are lacking, and cancer often is detected at advanced stages. Hypothesis/Objectives To examine how cancer typically is detected in dogs and whether the add
Externí odkaz:
https://doaj.org/article/d371ca1a414843748846f7200db24ee1
Autor:
Amadeo M. Parissenti, Laura B. Pritzker, Baoqing Guo, Rashmi Narendrula, Shirly Xiaohui Wang, Lin Laura Lin, Jingchun Pei, Karolina Skowronski, Dorothee Bienzle, J. Paul Woods, Kenneth P. H. Pritzker, Brenda L. Coomber
Publikováno v:
BMC Veterinary Research, Vol 15, Iss 1, Pp 1-9 (2019)
Abstract Background Assessment of the efficacy of a multi-agent chemotherapy protocol in which cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP) are administered in canine lymphoma is generally performed by physical measurement of lymp
Externí odkaz:
https://doaj.org/article/a52df3a346464507a40cce5c1ece003f
Autor:
Brenda L. Coomber, Janusz W. Rak, Senji Shirasawa, Claire Plumb, Courtney Stone, Lindsay Quayle, Siranoush Shahrzad
Data on K-ras mutation at codon 12 & 61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68aebd37c267ae4339e61d7ebe5d7e79
https://doi.org/10.1158/0008-5472.22364045.v1
https://doi.org/10.1158/0008-5472.22364045.v1
Autor:
Brenda L. Coomber, Janusz W. Rak, Senji Shirasawa, Claire Plumb, Courtney Stone, Lindsay Quayle, Siranoush Shahrzad
Mutation of the K-ras gene is one of the most common genetic alterations in solid tumors, including colorectal cancer. The relatively late emergence of K-ras mutations in colorectal cancer is particularly striking in the class of mismatch repair–de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300c95b32645106c14ecc10944e41d81
https://doi.org/10.1158/0008-5472.c.6493994.v1
https://doi.org/10.1158/0008-5472.c.6493994.v1
Publikováno v:
Veterinary Pathology
Mast cell tumors (MCTs) are the most common skin tumor of the dog, and accurately predicting their clinical behavior is critical in directing patient therapy, as they range from benign lesions to a fatal systemic disease. Grading is useful for progno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827e816c10bc90dcb357e6b02bf75e7c
https://doi.org/10.1177/03009858211042578
https://doi.org/10.1177/03009858211042578
Autor:
Andi Flory, Kristina M. Kruglyak, John A. Tynan, Lisa M. McLennan, Jill M. Rafalko, Patrick Christian Fiaux, Gilberto E. Hernandez, Francesco Marass, Prachi Nakashe, Carlos A. Ruiz-Perez, Donna M. Fath, Thuy Jennings, Rita Motalli-Pepio, Kate Wotrang, Angela L. McCleary-Wheeler, Susan Lana, Brenda Phillips, Brian K. Flesner, Nicole F. Leibman, Tracy LaDue, Chelsea D. Tripp, Brenda L. Coomber, J. Paul Woods, Mairin Miller, Sean W. Aiken, Amber Wolf-Ringwall, Antonella Borgatti, Kathleen Kraska, Christopher B. Thomson, Alane Kosanovich Cahalane, Rebecca L. Murray, William C. Kisseberth, Maria A. Camps-Palau, Franck Floch, Claire Beaudu-Lange, Aurélia Klajer-Peres, Olivier Keravel, Luc-André Fribourg-Blanc, Pascale Chicha Mazetier, Angelo Marco, Molly B. McLeod, Erin Portillo, Terry S. Clark, Scott Judd, C. Kirk Feinberg, Marie Benitez, Candace Runyan, Lindsey Hackett, Scott Lafey, Danielle Richardson, Sarah Vineyard, Mary Tefend Campbell, Nilesh Dharajiya, Taylor J. Jensen, Dirk van den Boom, Luis A. Diaz, Daniel S. Grosu, Arthur Polk, Kalle Marsal, Susan Cho Hicks, Katherine M. Lytle, Lauren Holtvoigt, Jason Chibuk, Ilya Chorny, Dana W. Y. Tsui
Publikováno v:
PloS one. 17(4)
Cancer is the leading cause of death in dogs, yet there are no established screening paradigms for early detection. Liquid biopsy methods that interrogate cancer-derived genomic alterations in cell-free DNA in blood are being adopted for multi-cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd0a6812d765df44f6f440d3d05bf01
https://pubmed.ncbi.nlm.nih.gov/35471999
https://pubmed.ncbi.nlm.nih.gov/35471999