Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Brenda Kwambana"'
Autor:
Akuzike Kalizang’oma, Damien Richard, Brenda Kwambana-Adams, Juliana Coelho, Karen Broughton, Bruno Pichon, Katie L. Hopkins, Victoria Chalker, Sandra Beleza, Stephen D. Bentley, Chrispin Chaguza, Robert S. Heyderman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Streptococcus mitis is a leading cause of infective endocarditis (IE). However, our understanding of the genomic epidemiology and pathogenicity of IE-associated S. mitis is hampered by low IE incidence. Here we use whole genome sequencing of
Externí odkaz:
https://doaj.org/article/ca029c9f70b5483cb69b90e930dd5730
Autor:
Jada Hackman, Martin L. Hibberd, Todd D. Swarthout, Jason Hinds, James Ashall, Carmen Sheppard, Gerry Tonkin-Hill, Kate Gould, Comfort Brown, Jacquline Msefula, Andrew A. Mataya, Michiko Toizumi, Lay-Myint Yoshida, Neil French, Robert S. Heyderman, Stefan Flasche, Brenda Kwambana, Stéphane Hué
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 12 (2024)
ABSTRACT Detection of multiple pneumococcal serotype carriage can enhance monitoring of pneumococcal vaccine impact, particularly among high-burden childhood populations. We assessed methods for identifying co-carriage of pneumococcal serotypes from
Externí odkaz:
https://doaj.org/article/6c26614227b24aa19cde38a869808de5
Autor:
Charlotte Davison, Sam Tallman, Megan de Ste-Croix, Martin Antonio, Marco R Oggioni, Brenda Kwambana-Adams, Fabian Freund, Sandra Beleza
Publikováno v:
PLoS Genetics, Vol 20, Iss 6, p e1011317 (2024)
Evaluation of the apportionment of genetic diversity of human bacterial commensals within and between human populations is an important step in the characterization of their evolutionary potential. Recent studies showed a correlation between the geno
Externí odkaz:
https://doaj.org/article/b5c6e34f629d44248299919d85cd9d4c
Autor:
Regina E. Abotsi, Felix S. Dube, Andrea M. Rehman, Shantelle Claassen-Weitz, Yao Xia, Victoria Simms, Kilaza S. Mwaikono, Sugnet Gardner-Lubbe, Grace McHugh, Lucky G. Ngwira, Brenda Kwambana-Adams, Robert S. Heyderman, Jon Ø. Odland, Rashida A. Ferrand, Mark P. Nicol, The BREATHE study team
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-19 (2023)
Abstract Background Long-term azithromycin (AZM) treatment reduces the frequency of acute respiratory exacerbation in children and adolescents with HIV-associated chronic lung disease (HCLD). However, the impact of this treatment on the respiratory b
Externí odkaz:
https://doaj.org/article/1a6ecb8a819d4ea8b8d835d6cf70b4c3
Autor:
Rebecca A. Gladstone, Stephanie W. Lo, John A. Lees, Nicholas J. Croucher, Andries J. van Tonder, Jukka Corander, Andrew J. Page, Pekka Marttinen, Leon J. Bentley, Theresa J. Ochoa, Pak Leung Ho, Mignon du Plessis, Jennifer E. Cornick, Brenda Kwambana-Adams, Rachel Benisty, Susan A. Nzenze, Shabir A. Madhi, Paulina A. Hawkins, Dean B. Everett, Martin Antonio, Ron Dagan, Keith P. Klugman, Anne von Gottberg, Lesley McGee, Robert F. Breiman, Stephen D. Bentley
Publikováno v:
EBioMedicine, Vol 43, Iss , Pp 338-346 (2019)
Background: Pneumococcal conjugate vaccines have reduced the incidence of invasive pneumococcal disease, caused by vaccine serotypes, but non-vaccine-serotypes remain a concern. We used whole genome sequencing to study pneumococcal serotype, antibiot
Externí odkaz:
https://doaj.org/article/4f78456e71ec429c89ae26a2c712815f
The impact of long-term azithromycin on antibiotic resistance in HIV-associated chronic lung disease
Autor:
Regina E. Abotsi, Mark P. Nicol, Grace McHugh, Victoria Simms, Andrea M. Rehman, Charmaine Barthus, Lucky G. Ngwira, Brenda Kwambana-Adams, Robert S. Heyderman, Jon Ø. Odland, Rashida A. Ferrand, Felix S. Dube
Publikováno v:
ERJ Open Research, Vol 8, Iss 1 (2021)
Selection for resistance to azithromycin (AZM) and other antibiotics such as tetracyclines and lincosamides remains a concern with long-term AZM use for treatment of chronic lung diseases (CLD). We investigated the impact of 48 weeks of AZM on the ca
Externí odkaz:
https://doaj.org/article/93642902441a46e8ada69346547adadd
Autor:
Brenda Kwambana-Adams, Blake Hanson, Archibald Worwui, Schadrac Agbla, Ebenezer Foster-Nyarko, Fatima Ceesay, Chinelo Ebruke, Uzochukwu Egere, Yanjiao Zhou, Maze Ndukum, Erica Sodergren, Michael Barer, Richard Adegbola, George Weinstock, Martin Antonio
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract There is growing concern that interventions that alter microbial ecology can adversely affect health. We characterised the impact of the seven-valent pneumococcal conjugate vaccine (PCV7) on pneumococcal carriage and the bacterial component
Externí odkaz:
https://doaj.org/article/5ba195074d474c23abecc345fe5659b3
Autor:
Saffiatou Darboe, Sarah Dobreniecki, Sheikh Jarju, Mamadou Jallow, Nuredin Ibrahim Mohammed, Miriam Wathuo, Buntung Ceesay, Sam Tweed, Robindra Basu Roy, Uduak Okomo, Brenda Kwambana-Adams, Martin Antonio, Richard S. Bradbury, Thushan I. de Silva, Karen Forrest, Anna Roca, Bolarinde Joseph Lawal, Davis Nwakanma, Ousman Secka
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Background:Staphylococcus aureus is a major human pathogen. Panton-Valentine leukocidin (PVL) is a virulence factor produced by some strains that causes leukocyte lysis and tissue necrosis. PVL-associated S. aureus (PVL-SA) predominantly causes skin
Externí odkaz:
https://doaj.org/article/0ff408155102417f9d39cf0c1f72e7fc
Autor:
Koirobi Haldar, Mona Bafadhel, Kelvin Lau, Adam Berg, Brenda Kwambana, Tatiana Kebadze, Mohammadali Yavari Ramsheh, Bethan Barker, Pranabashis Haldar, Sebastian Johnston, Julian M Ketley, Christopher E Brightling, Michael R Barer
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182833 (2017)
While a subgroup of patients with exacerbations of chronic obstructive pulmonary disease (COPD) clearly benefit from antibiotics, their identification remains challenging. We hypothesised that selective assessment of the balance between the two domin
Externí odkaz:
https://doaj.org/article/dcfdb232ee9445faa3db3a54164970ef
Publikováno v:
The Lancet Child & Adolescent Health. 7:299-301
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e36f7b39d629ff2ffd8a366366339f65
https://doi.org/10.1016/s2352-4642(23)00055-x
https://doi.org/10.1016/s2352-4642(23)00055-x