Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Brenda J. Burton"'
Autor:
Nicola E. Wilsher, Andrew J. Ratcliffe, Brenda J. Burton, Collis Alan John, Maria G. Belvisi, Iain Mcfarlane Mclay, Chris Maslen, Simon Phipps, Martyn Foster, Kenneth Page, Michael F. Kelley, Bryan Slater, Stephen E Webber, Jayyosi Zaid, Kenneth Pollock, V. Benning, Alex Constan, Elisabeth J. Redford, David J Hele, Jeffrey Mckenna, Glen K. Miller, Véronique Thybaud, Barry Porter, Frank Halley, Marie-Claude Ouldelhkim, Mark A. Birrell, John E. Souness
Publikováno v:
Bioorganic & Medicinal Chemistry. 9:537-554
RPR132331, a 2-(2-dioxanyl)imidazole, was identified as an inhibitor of tumour necrosis factor (TNF)alpha release from lipopolysaccharide (LPS)-stimulated human monocytes. An intensive programme of work exploring the biology, toxicity and physical ch
Autor:
Brenda J. Burton, Vincenzo Facchini, Akintunde A. Bello, Robert J. Williams, Parascevas P. Joannou, R.C. Bush, David P. Parrott, James H. Casey, Colin P. Bright, Dron Donald Ian, Roberts Simon, David Riddell
Publikováno v:
Biochemical Pharmacology. 51:413-421
RP 64477 (N-butyl-3-(p-decyloxybenzamido)-4-(methylthio)benzamide) has been shown to be a potent inhibitor of the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (EC 2.3.1.26; ACAT) in intestinal, hepatic, adrenal, and ar
Autor:
Brenda J. Burton, Colin P. Bright, R.C. Bush, Una M. Moore, David Hele, Robert J. Williams, David P. Parrott, Neil Victor Harris, Christopher Smith, Kuni Naik, David Riddell
Publikováno v:
Biochemical pharmacology. 52(8)
RP 73163 ((S)-2-[5-(3,5-dimethyl-l-pyrazolyl)pent-l-yl)-sulphinyl]-5, 6-diphenylimidazole) has been shown to be a potent and specific inhibitor of acyl-CoA:cholesterol acyltransferase (EC 2.3.1.26; ACAT) in vitro using the tissues of experimental ani