Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Brenda J. Boersma"'
Autor:
Stefan Ambs, David A. Wink, Stephen J. Chanock, Vessela N. Kristensen, Bjorn Naume, Anne-Lise Børresen-Dale, Per E. Lønning, Lisa A. Ridnour, Julie E. Goodman, Stephanie B. Geisler, Hege Edvardsen, Tiffany M. Howe, Brenda J. Boersma, Sharon A. Glynn
Supplementary Data from A Mitochondrial Target Sequence Polymorphism in Manganese Superoxide Dismutase Predicts Inferior Survival in Breast Cancer Patients Treated with Cyclophosphamide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505f94b94017f4ab1a3ce1c604ec4d3a
https://doi.org/10.1158/1078-0432.22440400.v1
https://doi.org/10.1158/1078-0432.22440400.v1
Autor:
Adrienne M Starks, Damali N Martin, Tiffany H Dorsey, Brenda J Boersma, Tiffany A Wallace, Stefan Ambs
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57361 (2013)
A study from Scotland reported that the p53 mutation frequency in breast tumors is associated with socio-economic deprivation.We analyzed the association of the tumor p53 mutational status with tumor characteristics, education, and self-reported annu
Externí odkaz:
https://doaj.org/article/3aca0c1899424857aeb8d3ce565546fb
Autor:
Damali N Martin, Brenda J Boersma, Ming Yi, Mark Reimers, Tiffany M Howe, Harry G Yfantis, Yien Che Tsai, Erica H Williams, Dong H Lee, Robert M Stephens, Allan M Weissman, Stefan Ambs
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4531 (2009)
African-American breast cancer patients experience higher mortality rates than European-American patients despite having a lower incidence of the disease. We tested the hypothesis that intrinsic differences in the tumor biology may contribute to this
Externí odkaz:
https://doaj.org/article/278b7c636a6a4ab28884f281f7f9d357
Autor:
Nigel P S Crawford, Xiaolan Qian, Argyrios Ziogas, Alex G Papageorge, Brenda J Boersma, Renard C Walker, Luanne Lukes, William L Rowe, Jinghui Zhang, Stefan Ambs, Douglas R Lowy, Hoda Anton-Culver, Kent W Hunter
Publikováno v:
PLoS Genetics, Vol 3, Iss 11, p e214 (2007)
A novel candidate metastasis modifier, ribosomal RNA processing 1 homolog B (Rrp1b), was identified through two independent approaches. First, yeast two-hybrid, immunoprecipitation, and functional assays demonstrated a physical and functional interac
Externí odkaz:
https://doaj.org/article/024d35a8a3384db88bf5b2ceca00f697
Autor:
Stephanie Geisler, Stephen J. Chanock, David A. Wink, Vessela N. Kristensen, Julie E. Goodman, Anne Lise Børresen-Dale, Bjørn Naume, Lisa A. Ridnour, Per Eystein Lønning, Tiffany M. Howe, Stefan Ambs, Sharon A. Glynn, Hege Edvardsen, Brenda J. Boersma
Publikováno v:
Clinical Cancer Research. 15:4165-4173
Purpose: Manganese superoxide dismutase protects against oxidative damage and modulates the efficacy of chemotherapeutic drugs. A functional single-nucleotide polymorphism in codon 16 of SOD2 (rs4880), which encodes manganese superoxide dismutase, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee38a380bec07f100084f4ea062dae73
https://doi.org/10.1158/1078-0432.ccr-09-0119
https://doi.org/10.1158/1078-0432.ccr-09-0119
Autor:
Dong H. Lee, Mark Reimers, Robert M. Stephens, John N. Weinstein, Stefan Ambs, Brenda J. Boersma, Harry G. Yfantis, Joseph A. Ludwig, Ming Yi, Brian T. Luke
Publikováno v:
International Journal of Cancer. 122:1324-1332
The factors that determine whether a breast carcinoma will develop into inflammatory breast cancer (IBC) remain poorly understood. Recent evidence indicates that the tumor stroma influences cancer phenotypes. We tested the hypotheses that the gene ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8da39572084d0fc60bcd8fc67aacf89a
https://doi.org/10.1002/ijc.23237
https://doi.org/10.1002/ijc.23237
Autor:
Lei Ying, Stefan Ambs, Brenda J. Boersma, Dong H. Lee, David A. Wink, John R. Cottrell, Douglas D. Thomas, Robyn L. Prueitt, Julie E. Goodman, Lorne J. Hofseth, Harris G. Yfantis, Candice M. Pfiester, Tiffany M. Howe, Alan T. Remaley
Publikováno v:
International Journal of Cancer. 120:796-805
Akt signaling may promote breast cancer progression and poor disease outcome. We hypothesized that serum insulin-like growth factor I (IGF-I) and a proinflammatory tumor environment induce phosphorylation of Akt and downstream targets of Akt in breas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::169a12b0b6bd2541d50a9ca0786279a5
https://doi.org/10.1002/ijc.22336
https://doi.org/10.1002/ijc.22336
Autor:
Dong H. Lee, Harry G. Yfantis, Julie E. Goodman, Stefan Ambs, Tiffany M. Howe, Stephen J. Chanock, Brenda J. Boersma
Publikováno v:
JNCI: Journal of the National Cancer Institute. 98:911-919
Background: A common single-nucleotide polymorphism (SNP) in the promoter region of the MDM2 gene, known as T-309G and referred to as SNP309 for this study, leads to increased expression of Mdm2 protein and attenuated function of the p53 tumor suppre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9badbcd27fbee5f9a43f78358b48ea7
https://doi.org/10.1093/jnci/djj245
https://doi.org/10.1093/jnci/djj245
Autor:
Nigel P. Botting, Victor M. Darley-Usmar, Brenda J. Boersma, Tracy D'Alessandro, Rakesh P. Patel, Landon Wilson, Jeevan K. Prasain, Stephen Barnes, Marion Kirk, Matthew R Benton
Publikováno v:
Free Radical Biology and Medicine. 35:1417-1430
Soy isoflavones and other polyphenolics have a number of potentially important beneficial effects on the pro-oxidant aspects of chronic inflammation. The impact of inflammatory cell-specific metabolism of polyphenolics, which can include halogenation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae29c41d2a6924d790e4f09d68e237ce
https://doi.org/10.1016/j.freeradbiomed.2003.08.009
https://doi.org/10.1016/j.freeradbiomed.2003.08.009
Autor:
Victor M. Darley-Usmar, Balaraman Kalyanaraman, Stephen Barnes, Brenda J. Boersma, Marion Kirk, Neil Hogg, Jack H. Crawford, Rakesh P. Patel, Dale A. Parks
Publikováno v:
Free Radical Biology and Medicine. 31:1570-1581
Oxidation of lipids has been implicated in the pathophysiology of atherosclerosis. It has been suggested that scavenging of lipid peroxyl radicals contribute to the antiatherosclerotic effects of naturally occurring compounds such as the isoflavones.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66bad2878cf65d49e37ec288ed69622
https://doi.org/10.1016/s0891-5849(01)00737-7
https://doi.org/10.1016/s0891-5849(01)00737-7