Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Brenda I. Hendriks-Stegeman"'
Autor:
C.E. van den Brink, S. C. van Buul-Offers, B. van der Burg, Brenda I. Hendriks-Stegeman, P. T. Van Der Saag, Maarten Jansen, Harry Vermeer
Publikováno v:
Clinical Endocrinology. 59:49-55
Summary objective Some patients develop side-effects even on relatively low doses of topically administered glucocorticoids (GCs), while others appear to be less sensitive to GCs. We have developed and validated a bioassay which can measure glucocort
Autor:
Harry Vermeer, Bart van der Burg, Brenda I. Hendriks-Stegeman, Maarten Jansen, Sylvia C. van Buul-Offers
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 88:277-284
To reduce the side effects of corticosteroid treatment, the administered dose of glucocorticoids (GCs) should be kept to a minimum while preserving therapeutically needed intracellular levels. Currently available assays to determine individual sensit
Autor:
Brenda I. Hendriks-Stegeman, Pieternella Holthuizen, Peter C. van der Vliet, Maarten Jansen, Bert Bakker, Kevin D. Augustijn
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 86:1545-1550
The POU homeodomain containing transcriptional activator POU1F1, formerly called Pit1 or GHF-1, is required for the embryological determination and postnatal secretory function of the GH-, PRL-, and TSH-producing cells in the anterior pituitary. Seve
Autor:
Maarten Jansen, A. A. Verrijn Stuart, Brenda I. Hendriks-Stegeman, S. C. van Buul-Offers, Harry Vermeer
Publikováno v:
European journal of endocrinology. 150(1)
An altered cellular glucocorticoid (GC) sensitivity is associated with several pathophysiological conditions such as asthma, diabetes, or rheumatoid arthritis. Several bioassays have been developed and employed to assess cellular GC sensitivity of pe
Autor:
Brenda I. Hendriks-Stegeman, Sylvia C. van Buul-Offers, Maarten Jansen, Denise van Suylekom, Harry Vermeer, Ger T. Rijkers
Publikováno v:
Molecular and cellular endocrinology. 218(1-2)
Individual variation in sensitivity to glucocorticoids (GCs) poses a dilemma to the clinician. Currently available assays to determine individual sensitivity to GCs either seem imprecise, or they are based on mitogen-activated lymphocytes, although m
Publikováno v:
Endocrinology. 140(12)
Overexpression of human insulin-like growth factor II (IGF-II) in transgenic mice does not result in increased overall body growth. The IGF-II overexpression, however, specifically causes growth of the thymus and not of the spleen. We address the que