Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Brenda G Byrne"'
Autor:
Clarissa L Durie, Michael J Sheedlo, Jeong Min Chung, Brenda G Byrne, Min Su, Thomas Knight, Michele Swanson, D Borden Lacy, Melanie D Ohi
Publikováno v:
eLife, Vol 9 (2020)
Legionella pneumophila is an opportunistic pathogen that causes the potentially fatal pneumonia Legionnaires’ Disease. This infection and subsequent pathology require the Dot/Icm Type IV Secretion System (T4SS) to deliver effector proteins into hos
Externí odkaz:
https://doaj.org/article/4e727e751c3643ba8cf52314be90d2c1
Autor:
Brenda G. Byrne, Sarah McColm, Shawn P. McElmurry, Paul E. Kilgore, Joanne Sobeck, Rick Sadler, Nancy G. Love, Michele S. Swanson
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT Coinciding with major changes to its municipal water system, Flint, MI, endured Legionnaires’ disease outbreaks in 2014 and 2015. By sampling premise plumbing in Flint in the fall of 2016, we found that 12% of homes harbored legionellae, a
Externí odkaz:
https://doaj.org/article/b5f4ff59727b4d24bae32d62c77ca9c8
Autor:
Brenda G. Byrne, Jean-Francois Dubuisson, Amrita D. Joshi, Jenny J. Persson, Michele S. Swanson
Publikováno v:
mBio, Vol 4, Iss 1 (2013)
ABSTRACT When microbes contaminate the macrophage cytoplasm, leukocytes undergo a proinflammatory death that is initiated by nucleotide-binding-domain-, leucine-rich-repeat-containing proteins (NLR proteins) that bind and activate caspase-1. We repor
Externí odkaz:
https://doaj.org/article/404522b7c4ea440996363903bb320f02
Autor:
Jeong Min Chung, Brenda G. Byrne, D. Borden Lacy, Michael J Sheedlo, Melanie D. Ohi, Thomas Knight, Min Su, Michele S. Swanson, Clarissa L Durie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c60382eded93900767a6548353a863c
https://doi.org/10.7554/elife.59530.sa2
https://doi.org/10.7554/elife.59530.sa2
Autor:
Jeong Min Chung, D.B. Lacy, Thomas Knight, Michele S. Swanson, Clarissa L Durie, Brenda G. Byrne, Michael J Sheedlo, Melanie D. Ohi
Publikováno v:
Microscopy and Microanalysis. 26:1814-1815
Publikováno v:
Journal of Bacteriology. 201
During its life cycle, the environmental pathogen Legionella pneumophila alternates between a replicative and transmissive cell type when cultured in broth, macrophages, or amoebae. Within a protozoan host, L. pneumophila further differentiates into
During its life cycle, the environmental pathogenLegionella pneumophilaalternates between a replicative and a transmissive cell type when cultured in broth, macrophages, or amoebae. Within a protozoan host,L. pneumophilafurther differentiates into th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef3e6c657c5d41e7c38d5c0ee30a3319
Publikováno v:
Infection and Immunity. 82:720-730
The phagosomal transporter (Pht) family of the major facilitator superfamily (MFS) is encoded by phylogenetically related intracellular gammaproteobacteria, including the opportunistic pathogen Legionella pneumophila . The location of the pht genes b
Autor:
Michele S. Swanson, Brenda G. Byrne, Daniel B. Kearns, Kaitlin J. Flynn, Sampriti Mukherjee, Zachary D. Abbott
Bacterial evolution is accelerated by mobile genetic elements. To spread horizontally and to benefit the recipient bacteria, genes encoded on these elements must be properly regulated. Among the legionellae are multiple integrative conjugative elemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc47be821954a41f04864fa65a3839ee
https://europepmc.org/articles/PMC4719454/
https://europepmc.org/articles/PMC4719454/
Publikováno v:
Autophagy. 1:53-58
Macrophages activate autophagy as an immediate response to Legionella pneumophila infection, but what marks the pathogen phagosome as a target for the autophagy machinery is not known. Because a variety of bacteria, parasites, viruses, and toxins tha