Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Brenda C M, de Winter"'
Autor:
Moska Hassanzai, Fadime Adanç, Birgit C P Koch, Nelianne J Verkaik, Jakob van Oldenrijk, Jorg L de Bruin, Brenda C M de Winter, Hein A W van Onzenoort
Publikováno v:
Therapeutic Advances in Infectious Disease, Vol 10 (2023)
Background: Outpatient Parenteral Antimicrobial Therapy (OPAT) is considered a patient-friendly and cost-effective practice. Patients in the OPAT service can be at risk for developing adverse events. Due to extensive variations in practice, guideline
Externí odkaz:
https://doaj.org/article/194be167cd79494b88bae650d4dfb2b7
Autor:
Lukas K. van Vugt, Marieke van der Zwan, Marian C. Clahsen-van Groningen, Madelon van Agteren, Daphne M. Hullegie-Peelen, Brenda C. M. De Winter, Marlies E. J. Reinders, Pedro Miranda Afonso, Dennis A. Hesselink
Publikováno v:
Transplant International, Vol 36 (2023)
Alemtuzumab is used as lymphocyte-depleting therapy for severe or glucocorticoid-resistant kidney transplant rejection. However, the long-term efficacy and toxicity of alemtuzumab therapy are unclear. Therefore, all cases of alemtuzumab anti-rejectio
Externí odkaz:
https://doaj.org/article/cfd685a2a41d4895a6c64720351229a2
Autor:
Rebecca A. Hermans, Lisa T. Ringeling, Kajie Liang, Sanne M. Kloosterboer, Brenda C. M. de Winter, Manon H. J. Hillegers, Birgit C. P. Koch, Bram Dierckx
Publikováno v:
BMC Psychiatry, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Antipsychotic drugs are an important part of the treatment of irritability and aggression in children with an autism spectrum disorder (ASD). However, significant weight gain and metabolic disturbances are clinically relevant side
Externí odkaz:
https://doaj.org/article/ce3abc5704a4411ab39fb8626c3ff432
Autor:
Letao Li, Sebastiaan D. T. Sassen, Tim M. J. Ewoldt, Alan Abdulla, Nicole G. M. Hunfeld, Anouk E. Muller, Brenda C. M. de Winter, Henrik Endeman, Birgit C. P. Koch
Publikováno v:
Antibiotics, Vol 12, Iss 2, p 383 (2023)
The number of pharmacokinetic (PK) models of meropenem is increasing. However, the daily role of these PK models in the clinic remains unclear, especially for critically ill patients. Therefore, we evaluated the published meropenem models on real-wor
Externí odkaz:
https://doaj.org/article/aa2133f593ba423898dabeb780442696
Autor:
Eveline E. Roelofsen, Brenda C. M. de Winter, Heleen van der Spek, Susan Snijders, Birgit C. P. Koch, Sanne van den Berg, Anouk E. Muller
Publikováno v:
Antibiotics, Vol 11, Iss 8, p 1049 (2022)
For decades, flucloxacillin has been used to treat methicillin-susceptible Staphylococcus aureus (MSSA). Little is still known about its pharmacodynamics (PD). The present study aimed to determine the pharmacokinetic (PK)/PD index and the PD-index va
Externí odkaz:
https://doaj.org/article/64a9676c538f474fb6d6c976d1244f6a
Autor:
Aart van der Meijden, Vincent Aranzana-Climent, Heleen van der Spek, Brenda C M de Winter, William Couet, Joseph Meletiadis, Anouk E Muller, Sanne van den Berg
Publikováno v:
The Journal of antimicrobial chemotherapy, 78(3), 832-839. Oxford University Press
BackgroundAlthough polymyxin B has been in use since the late 1950s, there have been limited studies done to unravel its pharmacokinetics (PK) and pharmacodynamics (PD) index.MethodsWe determined, in neutropenic infected mice, the PK, plasma protein
Autor:
Tim M. J. Ewoldt, Alan Abdulla, Wim J. R. Rietdijk, Anouk E. Muller, Brenda C. M. de Winter, Nicole G. M. Hunfeld, Ilse M. Purmer, Peter van Vliet, Evert-Jan Wils, Jasper Haringman, Annelies Draisma, Tom A. Rijpstra, Attila Karakus, Diederik Gommers, Henrik Endeman, Birgit C. P. Koch
Publikováno v:
Intensive Care Medicine, 48(12), 1760-1771. Springer-Verlag
PURPOSE: Individualising drug dosing using model-informed precision dosing (MIPD) of beta-lactam antibiotics and ciprofloxacin has been proposed as an alternative to standard dosing to optimise antibiotic efficacy in critically ill patients. However,
Autor:
Femke de Velde, Brenda C. M. de Winter, Michael N. Neely, Jan Strojil, Walter M. Yamada, Stephan Harbarth, Angela Huttner, Teun van Gelder, Birgit C. P. Koch, Anouk E. Muller, on behalf of the COMBACTE-NET Consortium
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2170 (2021)
Population pharmacokinetic modeling and simulation (M&S) are used to improve antibiotic dosing. Little is known about the differences in parametric and nonparametric M&S. Our objectives were to compare (1) the external validation of parametric and no
Externí odkaz:
https://doaj.org/article/fd2d4162d61a43c1a8ffc404ef98d7db
Autor:
Suwasin Udomkarnjananun, Marith I. Francke, Marjolein Dieterich, Daan van de Velde, Jeroen G. H. P. Verhoeven, Karin Boer, Marian C. Clahsen-Van Groningen, Brenda C. M. De Winter, Carla C. Baan, Dennis A. Hesselink
Publikováno v:
Therapeutic Drug Monitoring, 44(5), 625-632. Lippincott Williams & Wilkins
Background:Intracellular tacrolimus concentration in peripheral blood mononuclear cells (PBMCs) (TAC [PBMC]) has been proposed to better represent its active concentration than its whole blood concentration. As tacrolimus acts on T lymphocytes and ot
Autor:
Eveline E. Roelofsen, Alan Abdulla, Anouk E. Muller, Henrik Endeman, Diederik Gommers, Annemieke Dijkstra, Nicole G. M. Hunfeld, Brenda C. M. de Winter, Birgit C. P. Koch
Publikováno v:
British Journal of Clinical Pharmacology, 89(2), 705-713. Wiley-Blackwell Publishing Ltd
Aims: To describe the pharmacokinetics (PK) of cefotaxime as pre-emptive treatment in critically ill adult patients, including covariates and to determine the probability of target attainment (PTA) of different dosage regimens for Enterobacterales an