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pro vyhledávání: '"Brenda Brankin"'
Publikováno v:
Articles
This study explores the potential of Raman spectroscopy, coupled with multivariate regression techniques and a protein separation technique (ion exchange chromatography), to quantitatively monitor diagnostically relevant changes in high molecular wei
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https://arrow.tudublin.ie/scschbioart/199
https://arrow.tudublin.ie/scschbioart/199
Publikováno v:
British Journal of Biomedical Science. 69:147-153
Adherens junctions (AD and tight junctions (TJ) play a key role in maintaining the apical-basolateral polarity and cohesive structure of epithelial cells. These epithelial junctions are maintained by the interaction of several key proteins including
Autor:
Brenda Brankin, Brian J. Willett, M. G. Bexiga, Margaret J Hosie, John J. Callanan, David J. Brayden, Nicola F. Fletcher, J.-M. Jacque
Publikováno v:
Neuropathology and Applied Neurobiology. 35:592-602
AIMS In human immunodeficiency virus infection, macrophage-tropic and lymphotropic viruses exist in the host. Central nervous system (CNS) infection is an early and ongoing event, important to understand when developing strategies to treat infection.
Autor:
Brenda Brankin, Matthew Campbell, Gwyneth-Jane Farrar, Julie A. Kelly, Peter Humphries, Laurence O'dwyer, Paul F. Kenna, Christoph W. Blau, Christian Kerskens, Amanda Tivnan, Anna-Sophia Kiang
Publikováno v:
The Journal of Gene Medicine. 10:930-947
Background The blood-brain barrier (BBB) contains tight junctions (TJs) which reduce the space between adjacent endothelial cells lining the fine capillaries of the microvasculature of the brain to form a selective and regulatable barrier. Methods Us
Publikováno v:
Veterinary Immunology and Immunopathology. 123:134-137
Feline immunodeficiency virus (FIV), like human immunodeficiency virus (HIV)-1, is a neurotropic lentivirus and is associated with neuropathology in natural and experimental infections. FIV enters the brain early following experimental infection, and
Publikováno v:
Experimental Eye Research. 85:714-720
Retinitis Pigmentosa (RP) represents a major cause of progressive retinal disease worldwide and comprises a heterogeneous group of inherited diseases that are characterised by primary degeneration of rod photoreceptors and secondary degeneration of c
Publikováno v:
Acta Neuropathologica. 113:177-186
Previously we have employed antibodies to the tight junction (TJ)-associated proteins ZO-1 and occludin to describe endothelial tight junction abnormalities, in lesional and normal appearing white matter, in primary and secondary progressive multiple
Autor:
Alice N. McEvoy, Ross F Collery, Tom A. Gardiner, Alan W. Stitt, Matthew Campbell, Brenda Brankin
Publikováno v:
Current Eye Research. 31:1033-1045
This study aimed to evaluate the effects of endostatin on tight junction (TJ) integrity in retinal microvascular endothelial cells (RMECs) in vitro and in vivo. Moreover, it was hypothesized that endostatin-induced occludin upregulation regulated VEG
Publikováno v:
Anticancer research. 34(6)
The claudin family of proteins are key constituents of tight junctions and the aberrant expression of these proteins can contribute to de-stabilisation of tight junctions and thus to loss of cell polarity and cohesion. Increased expression of claudin
Publikováno v:
Articles
Small numbers of brain endothelial cells (BECs) are infected in children with neurologic complications of measles virus (MV) infection. This may provide a mechanism for virus entry into the central nervous system, but the mechanisms are unclear. Both