Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Brenda A. Truedell"'
Publikováno v:
Tetrahedron Letters. 22:295-298
The site of transition metal-directed acylations of apramycin and related aminoglycosides can be altered simply by changing the metal cation employed in the reaction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::321f5c52616e1b4723193ae2a4b24add
https://doi.org/10.1016/0040-4039(81)80079-2
https://doi.org/10.1016/0040-4039(81)80079-2
Autor:
John L. Ott, A. M. Felty-Duckworth, Manuel Debono, Brenda A. Truedell, K. E. Willard, F. T. Counter, Herbert A. Kirst, R. S. Pekarek, John E. Toth
Publikováno v:
The Journal of antibiotics. 39(8)
A large number and wide variety of acyl derivatives of the tylosin-related macrolides 23-demycinosyltylosin (DMT), 23-demycinosyloxytylosin (DMOT) and 5-O-mycaminosyltylonolide (OMT) were synthesized and evaluated. This encompassed conversion of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805de46e7e6c4290249a36a3d08b6ab1
https://pubmed.ncbi.nlm.nih.gov/3759662
https://pubmed.ncbi.nlm.nih.gov/3759662
Autor:
John L. Ott, Manuel Debono, A. M. Felty-Duckworth, Brenda A. Truedell, Herbert A. Kirst, John E. Toth, F. T. Counter, Robert S. Pekarek, K. E. Willard
Publikováno v:
Journal of medicinal chemistry. 31(8)
Modification of the aldehyde group in tylosin and related macrolide antibiotics dramatically enhanced the oral efficacy of the derivatives against experimental infections caused by susceptible bacteria in laboratory animals. A large number and wide v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed22114adc6560cef4c7ef5146f3927
https://pubmed.ncbi.nlm.nih.gov/3398001
https://pubmed.ncbi.nlm.nih.gov/3398001
Autor:
Herbert A. Kirst, J. R. Turner, Manuel Debono, K. E. Willard, John L. Ott, John E. Toth, David S. Fukuda, F. T. Counter, Dennis R. Berry, A. M. Felty-Duckworth, V. M. Daupert, Brenda A. Truedell, B. B. Briggs
Publikováno v:
The Journal of antibiotics. 39(12)
A large group of ester derivatives of tylosin-related macrolides was prepared in which the hydroxyl groups at C-3 and C-4'' were acylated by either chemical or biochemical methods. Most of the derivatives exhibited excellent in vitro antimicrobial ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb6e5c704747a624a6c33e5337e3a1f3
https://pubmed.ncbi.nlm.nih.gov/3818446
https://pubmed.ncbi.nlm.nih.gov/3818446