Zobrazeno 1 - 10 of 41 pro vyhledávání: '"Brenda A McManus"'
1
Akademický článek
Variations in candidalysin amino acid sequence influence toxicity and host responses
Autor: Don N. Wickramasinghe, Claire M. Lyon, Sejeong Lee, Olivia W. Hepworth, Emily L. Priest, Corinne Maufrais, Adam P. Ryan, Emmanuelle Permal, Derek Sullivan, Brenda A. McManus, Bernhard Hube, Geraldine Butler, Christophe d'Enfert, Julian R. Naglik, Jonathan P. Richardson
Publikováno v: mBio, Vol 15, Iss 8 (2024)
ABSTRACT Candida albicans causes millions of mucosal infections in humans annually. Hyphal overgrowth on mucosal surfaces is frequently associated with tissue damage caused by candidalysin, a secreted peptide toxin that destabilizes the plasma membra
Externí odkaz: https://doaj.org/article/3903d3d7c6d0456c8be1eb3b6dc95bad
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2
Akademický článek
Comparative Microbiological and Whole-Genome Analysis of Staphylococcus aureus Populations in the Oro-Nasal Cavities, Skin and Diabetic Foot Ulcers of Patients With Type 2 Diabetes Reveals a Possible Oro-Nasal Reservoir for Ulcer Infection
Autor: Brenda A. McManus, Blánaid Daly, Ioannis Polyzois, Pauline Wilson, Gráinne I. Brennan, Tanya E. Fleming, Liam D. Grealy, Marie-Louise Healy, David C. Coleman
Publikováno v: Frontiers in Microbiology, Vol 11 (2020)
Patients with type 2 diabetes are at higher risk for periodontal disease and diabetic foot ulcer infections (DFUIs), the latter of which are predominantly caused by staphylococcal bacteria. Staphylococci have also been detected in the mouth, nose and
Externí odkaz: https://doaj.org/article/b27e0a41b9d3488baeb43f1dc8881a99
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3
Akademický článek
Significant Enrichment and Diversity of the Staphylococcal Arginine Catabolic Mobile Element ACME in Staphylococcus epidermidis Isolates From Subgingival Peri-implantitis Sites and Periodontal Pockets
Autor: Aoife M. O’Connor, Brenda A. McManus, Peter M. Kinnevey, Gráinne I. Brennan, Tanya E. Fleming, Phillipa J. Cashin, Michael O’Sullivan, Ioannis Polyzois, David C. Coleman
Publikováno v: Frontiers in Microbiology, Vol 9 (2018)
Staphylococcus aureus and Staphylococcus epidermidis are frequent commensals of the nares and skin and are considered transient oral residents. Reports on their prevalence in the oral cavity, periodontal pockets and subgingivally around infected oral
Externí odkaz: https://doaj.org/article/f6b9d08f073e426fae5b8242e3a5fb39
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4
Akademický článek
The Emergence and Spread of Multiple Livestock-Associated Clonal Complex 398 Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Strains among Animals and Humans in the Republic of Ireland, 2010-2014.
Autor: Gráinne I Brennan, Yvonne Abbott, Aisling Burns, Finola Leonard, Brenda A McManus, Brian O'Connell, David C Coleman, Anna C Shore
Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0149396 (2016)
Clonal complex (CC) 398 methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible S. aureus (MSSA) are associated with carriage and infection among animals and humans but only a single case of CC398 MRSA has been reported in the
Externí odkaz: https://doaj.org/article/59c21a5659004df1aa1426ebf4d1c54c
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5
Genomic analysis of 600 vancomycin-resistant Enterococcus faecium reveals a high prevalence of ST80 and spread of similar vanA regions via IS1216E and plasmid transfer in diverse genetic lineages in Ireland
Autor: Henrik Westh, Gráinne I. Brennan, Brian O'Connell, Anna C. Shore, Sarah Mollerup, Brenda A. McManus, David C. Coleman, José Alfredo Samaniego Castruita, Sarah A Egan, Mette Pinholt, Nicole L Kavanagh
Publikováno v: Egan, S A, Kavanagh, N L, Shore, A C, Mollerup, S, Samaniego Castruita, J A, O’connell, B, Mcmanus, B A, Brennan, G I, Pinholt, M, Westh, H & Coleman, D C 2022, ' Genomic analysis of 600 vancomycin-resistant Enterococcus faecium reveals a high prevalence of ST80 and spread of similar vanA regions via IS1216E and plasmid transfer in diverse genetic lineages in Ireland ', Journal of Antimicrobial Chemotherapy, vol. 77, no. 2, pp. 320-330 . https://doi.org/10.1093/jac/dkab393
Journal of Antimicrobial Chemotherapy
Background Vancomycin-resistant Enterococcus faecium (VREfm) cause a wide range of hospital infections. Ireland has had one of the highest invasive VREfm infection rates in Europe over the last decade, yet little is known about Irish VREfm. Objective
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825c82b3883a76aaa0d906c67f4ea4b8
https://curis.ku.dk/ws/files/321275750/Genomic_analysis_of_600_vancomycin_resistant.pdf
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6
Akademický článek
Genetic Differences between Avian and Human Isolates of Candida dubliniensis
Autor: Brenda A. McManus, Derek J. Sullivan, Gary P. Moran, Christophe d’Enfert, Marie-Elisabeth Bougnoux, Miles A. Nunn, David C. Coleman
Publikováno v: Emerging Infectious Diseases, Vol 15, Iss 9, Pp 1467-1470 (2009)
When Candida dubliniensis isolates obtained from seabird excrement and from humans in Ireland were compared by using multilocs sequence typing, 13 of 14 avian isolates were genetically distinct from human isolates. The remaining avian isolate was ind
Externí odkaz: https://doaj.org/article/6f90e9ad88894cb7bf0db83fb521490b
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7
Akademický článek
Comparative Genotypes, Staphylococcal Cassette Chromosome mec (SCCmec) Genes and Antimicrobial Resistance amongst Staphylococcus epidermidis and Staphylococcus haemolyticus Isolates from Infections in Humans and Companion Animals.
Autor: Brenda A McManus, David C Coleman, Emily C Deasy, Gráinne I Brennan, Brian O' Connell, Stefan Monecke, Ralf Ehricht, Bernadette Leggett, Nola Leonard, Anna C Shore
Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0138079 (2015)
This study compares the characteristics of Staphylococcus epidermidis (SE) and Staphylococcus haemolyticus (SH) isolates from epidemiologically unrelated infections in humans (Hu) (28 SE-Hu; 8 SH-Hu) and companion animals (CpA) (12 SE-CpA; 13 SH-CpA)
Externí odkaz: https://doaj.org/article/56cba5367f2c427a9a71b904d1ddc212
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8
Akademický článek
Genotyping Candida albicans from Candida leukoplakia and non-Candida leukoplakia shows no enrichment of multilocus sequence typing clades but enrichment of ABC genotype C in Candida leukoplakia.
Autor: Mohammed H Abdulrahim, Brenda A McManus, Stephen R Flint, David C Coleman
Publikováno v: PLoS ONE, Vol 8, Iss 9, p e73738 (2013)
Oral leukoplakias are histopathologically-diagnosed as Candida leukoplakia or non-Candida leukoplakia by the presence or absence of hyphae in the superficial epithelium. Candida leukoplakia lesions have significantly increased malignant potential. Ca
Externí odkaz: https://doaj.org/article/aa52ddb629a0409891ccef0f051f39c1
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9
Multiple distinct outbreaks of Panton-Valentine leucocidin-positive community-associated meticillin-resistant Staphylococcus aureus in Ireland investigated by whole-genome sequencing
Autor: Ralf Ehricht, Stefan Monecke, Brenda A. McManus, Gráinne I. Brennan, Megan R. Earls, Brian O'Connell, B.K. Aloba, David C. Coleman, Anna C. Shore
Publikováno v: The Journal of hospital infection. 108
Summary Background Panton–Valentine leucocidin (PVL)-positive community-associated meticillin-resistant Staphylococcus aureus (CA-MRSA) is increasingly associated with infection outbreaks. Aim To investigate multiple suspected PVL-positive CA-MRSA
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90de5434999c4848eabb7c0109988621
https://pubmed.ncbi.nlm.nih.gov/33259881
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