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Autor:
Davis, Angharad G, Donovan, Joseph, Bremer, Marise, Van Toorn, Ronald, Schoeman, Johan, Dadabhoy, Ariba, Lai, Rachel PJ, Cresswell, Fiona V, Boulware, David R, Wilkinson, Robert J, Thuong, Nguyen Thuy Thuong, Thwaites, Guy E, Bahr, Nathan C, Tuberculous Meningitis International Research Consortium
A dysregulated host immune response significantly contributes to morbidity and mortality in tuberculous meningitis (TBM). Effective host directed therapies (HDTs) are critical to improve survival and clinical outcomes. Currently only one HDT, dexamet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1796710a1be5ffce5f8e05adce6b85
Akademický článek
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Autor:
Davis, Angharad G, Wasserman, Sean, Stek, Cari, Maxebengula, Mpumi, Liang, C Jason, Stegmann, Stephani, Koekemoer, Sonya, Jackson, Amanda, Kadernani, Yakub, Bremer, Marise, Daroowala, Remy, Aziz, Saalikha, Goliath, Rene, Sai, Louise Lai, Sihoyiya, Thandi, Denti, Paolo, Lai, Rachel P J, Crede, Thomas, Naude, Jonathan, Szymanski, Patryk
Publikováno v:
Clinical Infectious Diseases; 4/15/2023, Vol. 76 Issue 8, p1412-1422, 11p
Akademický článek
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Akademický článek
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Autor:
Davis AG; University College London, Gower Street, London, WC1E 6BT, UK.; The Francis Crick Institute, Midland Road, London, NW1 1AT, UK.; Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, 7925, South Africa., Donovan J; Oxford University Clinical Research Unit, Centre for Tropical Medicine, Ho Chi Minh City, Vietnam.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Bremer M; Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, 7925, South Africa., Van Toorn R; Department of Pediatrics and Child Health, Stellenbosch University, Cape Town, 7505, South Africa., Schoeman J; Department of Pediatrics and Child Health, Stellenbosch University, Cape Town, 7505, South Africa., Dadabhoy A; Division of Infectious Diseases, Department of Medicine, University of Kansas, Kansas City, KS, USA., Lai RPJ; The Francis Crick Institute, Midland Road, London, NW1 1AT, UK.; Department of Infectious Diseases, Imperial College London, London, W12 0NN, UK., Cresswell FV; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.; Infectious Diseases Institute, Makerere University, Kampala, Uganda., Boulware DR; Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN, USA., Wilkinson RJ; University College London, Gower Street, London, WC1E 6BT, UK.; The Francis Crick Institute, Midland Road, London, NW1 1AT, UK.; Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, 7925, South Africa.; Department of Infectious Diseases, Imperial College London, London, W12 0NN, UK., Thuong NTT; Oxford University Clinical Research Unit, Centre for Tropical Medicine, Ho Chi Minh City, Vietnam.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Thwaites GE; Oxford University Clinical Research Unit, Centre for Tropical Medicine, Ho Chi Minh City, Vietnam.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Bahr NC; Division of Infectious Diseases, Department of Medicine, University of Kansas, Kansas City, KS, USA.
Publikováno v:
Wellcome open research [Wellcome Open Res] 2021 Jul 01; Vol. 5, pp. 292. Date of Electronic Publication: 2021 Jul 01 (Print Publication: 2020).
Autor:
Davis AG; The Francis Crick Institute, Midland Rd, London, NW1 1AT, UK.; Faculty of Life Sciences, University College London, London, WC1E 6BT, UK.; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory, Cape Town, 7925, South Africa., Wasserman S; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory, Cape Town, 7925, South Africa.; Department of Medicine, University of Cape Town, Observatory, 7925, South Africa., Maxebengula M; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory, Cape Town, 7925, South Africa., Stek C; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory, Cape Town, 7925, South Africa.; Department of Infectious Diseases, Imperial College London, London, W12 0NN, UK., Bremer M; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory, Cape Town, 7925, South Africa., Daroowala R; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory, Cape Town, 7925, South Africa.; Department of Infectious Diseases, Imperial College London, London, W12 0NN, UK., Aziz S; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory, Cape Town, 7925, South Africa., Goliath R; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory, Cape Town, 7925, South Africa., Stegmann S; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory, Cape Town, 7925, South Africa., Koekemoer S; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory, Cape Town, 7925, South Africa., Jackson A; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory, Cape Town, 7925, South Africa., Lai Sai L; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory, Cape Town, 7925, South Africa., Kadernani Y; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory, Cape Town, 7925, South Africa., Sihoyiya T; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory, Cape Town, 7925, South Africa., Liang CJ; Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, Maryland, USA., Dodd L; Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, Maryland, USA., Denti P; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Observatory, 7925, South Africa., Crede T; Mitchells Plain Hospital, 8 A Z Berman Drive, Lentegeur, Cape Town, 7785, South Africa., Naude J; Mitchells Plain Hospital, 8 A Z Berman Drive, Lentegeur, Cape Town, 7785, South Africa., Szymanski P; Mitchells Plain Hospital, 8 A Z Berman Drive, Lentegeur, Cape Town, 7785, South Africa., Vallie Y; New Somerset Hospital, Portswood Rd, Green Point, Cape Town, 8051, South Africa., Banderker I; New Somerset Hospital, Portswood Rd, Green Point, Cape Town, 8051, South Africa., Moosa S; New Somerset Hospital, Portswood Rd, Green Point, Cape Town, 8051, South Africa., Raubenheimer P; Department of Medicine, University of Cape Town, Observatory, 7925, South Africa., Lai RPJ; The Francis Crick Institute, Midland Rd, London, NW1 1AT, UK.; Department of Infectious Diseases, Imperial College London, London, W12 0NN, UK., Joska J; Department of Psychiatry and Mental Health, HIV Mental Health Research Unit, Neuroscience Institute, University of Cape Town, Observatory, 7925, South Africa., Nightingale S; Department of Psychiatry and Mental Health, HIV Mental Health Research Unit, Neuroscience Institute, University of Cape Town, Observatory, 7925, South Africa., Dreyer A; Department of Psychiatry and Mental Health, HIV Mental Health Research Unit, Neuroscience Institute, University of Cape Town, Observatory, 7925, South Africa., Wahl G; Department of Medicine, Water Sisulu University, Mthatha, 5117, South Africa., Offiah C; Department of Neuroradiology, Imaging Department, Royal London Hospital, Barts Health NHS Trust, London, E1 1BB, UK., Vorster I; Division of Diagnostic Radiology, University of Cape Town, Groote Schuur Hospital, Observatory, 7925, South Africa., Candy S; Division of Diagnostic Radiology, University of Cape Town, Groote Schuur Hospital, Observatory, 7925, South Africa., Robertson F; MRC/UCT Medical Imaging Research Unit Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Observatory, 7925, South Africa., Meintjes E; MRC/UCT Medical Imaging Research Unit Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Observatory, 7925, South Africa., Maartens G; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Observatory, 7925, South Africa., Black J; Department of Medicine, Water Sisulu University, Mthatha, 5117, South Africa., Meintjes G; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory, Cape Town, 7925, South Africa.; Department of Medicine, University of Cape Town, Observatory, 7925, South Africa., Wilkinson RJ; The Francis Crick Institute, Midland Rd, London, NW1 1AT, UK.; Faculty of Life Sciences, University College London, London, WC1E 6BT, UK.; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory, Cape Town, 7925, South Africa.; Department of Medicine, University of Cape Town, Observatory, 7925, South Africa.; Department of Infectious Diseases, Imperial College London, London, W12 0NN, UK.
Publikováno v:
Wellcome open research [Wellcome Open Res] 2021 Jun 01; Vol. 6, pp. 136. Date of Electronic Publication: 2021 Jun 01 (Print Publication: 2021).
Autor:
Davis AG; University College London, Gower Street, London, WC1E 6BT, UK.; The Francis Crick Institute, Midland Road, London, NW1 1AT, UK.; Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, 7925, South Africa., Donovan J; Oxford University Clinical Research Unit, Centre for Tropical Medicine, Ho Chi Minh City, Vietnam.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Bremer M; Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, 7925, South Africa., Van Toorn R; Department of Pediatrics and Child Health, Stellenbosch University, Cape Town, 7505, South Africa., Schoeman J; Department of Pediatrics and Child Health, Stellenbosch University, Cape Town, 7505, South Africa., Dadabhoy A; Division of Infectious Diseases, Department of Medicine, University of Kansas, Kansas City, KS, USA., Lai RPJ; The Francis Crick Institute, Midland Road, London, NW1 1AT, UK.; Department of Infectious Diseases, Imperial College London, London, W12 0NN, UK., Cresswell FV; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.; Infectious Diseases Institute, Makerere University, Kampala, Uganda., Boulware DR; Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN, USA., Wilkinson RJ; University College London, Gower Street, London, WC1E 6BT, UK.; The Francis Crick Institute, Midland Road, London, NW1 1AT, UK.; Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, 7925, South Africa.; Department of Infectious Diseases, Imperial College London, London, W12 0NN, UK., Thuong NTT; Oxford University Clinical Research Unit, Centre for Tropical Medicine, Ho Chi Minh City, Vietnam.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Thwaites GE; Oxford University Clinical Research Unit, Centre for Tropical Medicine, Ho Chi Minh City, Vietnam.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Bahr NC; Division of Infectious Diseases, Department of Medicine, University of Kansas, Kansas City, KS, USA.
Publikováno v:
Wellcome open research [Wellcome Open Res] 2020 Dec 23; Vol. 5, pp. 292. Date of Electronic Publication: 2020 Dec 23 (Print Publication: 2020).