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pro vyhledávání: '"Brem, J."'
Akademický článek
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Publikováno v:
Revista Veterinaria; 2023, Vol. 34 Issue 2, p111-116, 6p
Autor:
Wendel Garcia P. D., Aguirre-Bermeo H., Buehler P. K., Alfaro-Farias M., Yuen B., David S., Tschoellitsch T., Wengenmayer T., Korsos A., Fogagnolo A., Kleger G. -R., Wu M. A., Colombo R., Turrini F., Potalivo A., Rezoagli E., Rodriguez-Garcia R., Castro P., Lander-Azcona A., Martin-Delgado M. C., Lozano-Gomez H., Ensner R., Michot M. P., Gehring N., Schott P., Siegemund M., Merki L., Wiegand J., Jeitziner M. M., Laube M., Salomon P., Hillgaertner F., Dullenkopf A., Ksouri H., Cereghetti S., Grazioli S., Burkle C., Marrel J., Fleisch I., Perez M. -H., Baltussen Weber A., Ceruti S., Marquardt K., Hubner T., Redecker H., Studhalter M., Stephan M., Selz D., Pietsch U., Ristic A., Heise A., Meyer zu Bentrup F., Franchitti Laurent M., Fodor P., Gaspert T., Haberthuer C., Colak E., Heuberger D. M., Fumeaux T., Montomoli J., Guerci P., Schuepbach R. A., Hilty M. P., Roche-Campo F., Algaba-Calderon A., Apolo J., Aslanidis T., Babik B., Boroli F., Brem J., Brenni M., Brugger S. D., Camen G., Catena E., Ceriani R., Chau I., Christ A., Cogliati C., Concha P., Delahaye G., Drvaric I., Escos-Orta J., Fabbri S., Facondini F., Filipovic M., Gamez-Zapata J., Gerecke P., Gommers D., Hillermann T., Ince C., Jenni-Moser B., Jovic M., Jurkolow G., Klarer A., Lambert A., Laurent J. -C., Lavanchy J., Lienhardt-Nobbe B., Locher P., Losser M. -R., Lussman R. F., Magliocca A., Margarit A., Martinez A., Mauri R., Mayor-Vazquez E., Meier J., Moret-Bochatay M., Murrone M., Naon D., Neff T., Novy E., Petersen L., Pugin J., Ramelet A. -S., Rilinger J., Rimensberger P. C., Sepulcri M., Shaikh K., Sieber M., Simonini M. S., Spadaro S., Sridharan G. O., Stahl K., Staudacher D. L., Taboada-Fraga X., Tellez A., Urech S., Vitale G., Vizmanos-Lamotte G., Welte T., Zalba-Etayo B., Zellweger N.
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Critical Care
Critical Care, 25(1):175. Springer Science + Business Media
Critical Care, Vol 25, Iss 1, Pp 1-12 (2021)
Critical care, vol. 25, no. 1, pp. 175
Wendel Garcia, Pedro D; Aguirre-Bermeo, Hernán; Buehler, Philipp K; Alfaro-Farias, Mario; Yuen, Bernd; David, Sascha; Tschoellitsch, Thomas; Wengenmayer, Tobias; Korsos, Anita; Fogagnolo, Alberto; Kleger, Gian-Reto; Wu, Maddalena A; Colombo, Riccardo; Turrini, Fabrizio; Potalivo, Antonella; Rezoagli, Emanuele; Rodríguez-García, Raquel; Castro, Pedro; Lander-Azcona, Arantxa; Martín-Delgado, Maria C; ... (2021). Implications of early respiratory support strategies on disease progression in critical COVID-19: a matched subanalysis of the prospective RISC-19-ICU cohort. Critical care, 25(1), p. 175. BioMed Central 10.1186/s13054-021-03580-y
Critical Care, 25(1):175. BioMed Central Ltd.
Universidad de Barcelona
Critical Care
Critical Care, 25(1):175. Springer Science + Business Media
Critical Care, Vol 25, Iss 1, Pp 1-12 (2021)
Critical care, vol. 25, no. 1, pp. 175
Wendel Garcia, Pedro D; Aguirre-Bermeo, Hernán; Buehler, Philipp K; Alfaro-Farias, Mario; Yuen, Bernd; David, Sascha; Tschoellitsch, Thomas; Wengenmayer, Tobias; Korsos, Anita; Fogagnolo, Alberto; Kleger, Gian-Reto; Wu, Maddalena A; Colombo, Riccardo; Turrini, Fabrizio; Potalivo, Antonella; Rezoagli, Emanuele; Rodríguez-García, Raquel; Castro, Pedro; Lander-Azcona, Arantxa; Martín-Delgado, Maria C; ... (2021). Implications of early respiratory support strategies on disease progression in critical COVID-19: a matched subanalysis of the prospective RISC-19-ICU cohort. Critical care, 25(1), p. 175. BioMed Central 10.1186/s13054-021-03580-y
Critical Care, 25(1):175. BioMed Central Ltd.
Background Uncertainty about the optimal respiratory support strategies in critically ill COVID-19 patients is widespread. While the risks and benefits of noninvasive techniques versus early invasive mechanical ventilation (IMV) are intensely debated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a33199e284c8f36775eb58d5f3b5498
http://hdl.handle.net/2445/186729
http://hdl.handle.net/2445/186729
Akademický článek
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Publikováno v:
Proceedings of the National Academy of Sciences. 119
β-Lactams are the most important class of antibacterials, but their use is increasingly compromised by resistance, most importantly via serine β-lactamase (SBL)-catalyzed hydrolysis. The scope of β-lactam antibacterial activity can be substantiall
Akademický článek
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Autor:
GOWAR, Mrs ZAHN, Rydzik, AM, Brem, J, Chandler, SA, Benesch, JLP, Claridge, TDW, Schofield, CJ
19F NMR protein observed spectroscopy is evaluated as a method for analysing protein metal binding using the New Delhi metallo-β-lactamase 1. The results imply 19F NMR is useful for analysis of different metallated protein states and investigations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::738aa20ec8b5683344301e6652378c67
https://doi.org/10.1039/c9md00416e
https://doi.org/10.1039/c9md00416e
Autor:
Parkova, A, Lucic, A, Krajnc, A, Brem, J, Calvopiña, K, Langley, GW, McDonough, MA, Trapencieris, P, Schofield, CJ
Publikováno v:
ACS infectious diseases. 6(6)
β-Lactamases comprise the most widely used mode of resistance to β-lactam antibiotics. Cyclic boronates have shown promise as a new class of β-lactamase inhibitor, with pioneering potential to potently inhibit both metallo- and serine-β-lactamase
Autor:
Zamiri, A., Pourboghrat, F., Jiang, H., Bieler, T.R., Barlat, F., Brem, J., Compton, C., Grimm, T.L.
Publikováno v:
In Materials Science & Engineering A 2006 435:658-665
Autor:
Krajnc, A, Brem, J, Hinchliffe, P, Calvopiña, K, Panduwawala, TD, Lang, PA, Kamps, JJAG, Tyrrell, JM, Widlake, E, Saward, BG, Walsh, TR, Spencer, J, Schofield, CJ
Publikováno v:
Journal of Medicinal Chemistry
Krajnc, A, Brem, J, Hinchliffe, P, Calvopina, K A, Panduwawala, T D, Lang, P, Kamps, J J A G, Tyrrell, J M, Widlake, E, Saward, B G, Walsh, T R, Spencer, J & Schofield, C J 2019, ' Bicyclic Boronate VNRX-5133 Inhibits Metallo-and Serine-β-Lactamases ', Journal of Medicinal Chemistry, vol. 62, no. 18, pp. 8544-8556 . https://doi.org/10.1021/acs.jmedchem.9b00911
Krajnc, A, Brem, J, Hinchliffe, P, Calvopina, K A, Panduwawala, T D, Lang, P, Kamps, J J A G, Tyrrell, J M, Widlake, E, Saward, B G, Walsh, T R, Spencer, J & Schofield, C J 2019, ' Bicyclic Boronate VNRX-5133 Inhibits Metallo-and Serine-β-Lactamases ', Journal of Medicinal Chemistry, vol. 62, no. 18, pp. 8544-8556 . https://doi.org/10.1021/acs.jmedchem.9b00911
The bicyclic boronate VNRX-5133 (taniborbactam) is a new type of β-lactamase inhibitor in clinical development. We report that VNRX-5133 inhibits serine-β-lactamases (SBLs) and some clinically important metallo-β-lactamases (MBLs), including NDM-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::389e3f8a9e9d77616787dcd444f15990
https://doi.org/10.1021/acs.jmedchem.9b00911
https://doi.org/10.1021/acs.jmedchem.9b00911