Zobrazeno 1 - 10
of 689
pro vyhledávání: '"Breitling Rainer"'
Autor:
Chua, Jeremy, Hanko, Erik K.R., Yiakoumetti, Andrew, Stoney, Ruth A., Chromy, Jakub, Valdehuesa, Kris Niño G., Hollywood, Katherine A., Yan, Cunyu, Takano, Eriko, Breitling, Rainer
Publikováno v:
In Metabolic Engineering Communications June 2024 18
Publikováno v:
BMC Research Notes, Vol 4, Iss 1, p 325 (2011)
Abstract Background Streptomyces coelicolor, a model organism of antibiotic producing bacteria, has one of the largest genomes of the bacterial kingdom, including 7825 predicted protein coding genes. A large number of these genes, nearly 34%, are fun
Externí odkaz:
https://doaj.org/article/08568912a0ed4baa86f15e8c96b9c92f
Publikováno v:
BMC Bioinformatics, Vol 11, Iss 1, p 497 (2010)
Abstract Background Large microarray datasets have enabled gene regulation to be studied through coexpression analysis. While numerous methods have been developed for identifying differentially expressed genes between two conditions, the field of dif
Externí odkaz:
https://doaj.org/article/379060c464704520944c31dfd8ac6697
Autor:
Wellington Elizabeth MH, Hodgson David A, Merlo Maria E, Alam Mohammad T, Takano Eriko, Breitling Rainer
Publikováno v:
BMC Genomics, Vol 11, Iss 1, p 202 (2010)
Abstract Background The transition from exponential to stationary phase in Streptomyces coelicolor is accompanied by a major metabolic switch and results in a strong activation of secondary metabolism. Here we have explored the underlying reorganizat
Externí odkaz:
https://doaj.org/article/92ff542eca92468f9757bdf7cbe250eb
Autor:
Bonin Michael, Wild David L, Rand David A, Dijkhuizen Lubbert, Jansen Ritsert C, Challis Gregory L, Legaie Roxane, Gaze William H, Iqbal Mudassar, Thomas Louise, Nentwich Merle, Rodríguez-García Antonio, Juarez-Hermosillo Miguel A, Morrissey Edward R, Omara Walid AM, Moore Jonathan, Merlo Maria E, Alam Mohammad T, Sletta Håvard, Jakobsen Øyvind M, Wentzel Alexander, Bruheim Per, Herbig Alexander, Battke Florian, Nieselt Kay, Reuther Jens, Wohlleben Wolfgang, Smith Margaret CM, Burroughs Nigel J, Martín Juan F, Hodgson David A, Takano Eriko, Breitling Rainer, Ellingsen Trond E, Wellington Elizabeth MH
Publikováno v:
BMC Genomics, Vol 11, Iss 1, p 10 (2010)
Abstract Background During the lifetime of a fermenter culture, the soil bacterium S. coelicolor undergoes a major metabolic switch from exponential growth to antibiotic production. We have studied gene expression patterns during this switch, using a
Externí odkaz:
https://doaj.org/article/aefdd039c17547fbb95acebc73dd8884
Autor:
Doerr Hans W, Hinsch Nora, Mayer Bernd, Breitling Rainer, Suhan Tatyana, Barth Susanne, Klassert Denise, Michaelis Martin, Cinatl Jaroslav, Cinatl Jindrich
Publikováno v:
Molecular Cancer, Vol 8, Iss 1, p 80 (2009)
Abstract Background Chemoresistance acquisition may influence cancer cell biology. Here, bioinformatics analysis of gene expression data was used to identify chemoresistance-associated changes in neuroblastoma biology. Results Bioinformatics analysis
Externí odkaz:
https://doaj.org/article/548e5fb2f7e74fe2b6a5ccab32610e1c
Publikováno v:
BMC Bioinformatics, Vol 10, Iss 1, p 188 (2009)
Abstract Background High-dimensional biomolecular profiling of genetically different individuals in one or more environmental conditions is an increasingly popular strategy for exploring the functioning of complex biological systems. The optimal desi
Externí odkaz:
https://doaj.org/article/68f71fc0acaf4ffbb17fcda2a315ab74
Autor:
van Hijum Sacha AFT, Roerdink Jos BTM, Hofstede Klaas, Breitling Rainer, Blom Evert, Kuipers Oscar P
Publikováno v:
BMC Genomics, Vol 9, Iss 1, p 495 (2008)
Abstract Background Despite a plethora of functional genomic efforts, the function of many genes in sequenced genomes remains unknown. The increasing amount of microarray data for many species allows employing the guilt-by-association principle to pr
Externí odkaz:
https://doaj.org/article/0eeaa1ca53184e26969c7b5f70004cf9
Autor:
Nap Jan-Peter, Breitling Rainer, de Haan Gerald, Bystrykh Leonid V, Hardonk Menno, Terpstra Peter, Alberts Rudi, Jansen Ritsert C
Publikováno v:
BMC Bioinformatics, Vol 8, Iss 1, p 132 (2007)
Abstract Background The Affymetrix GeneChip technology uses multiple probes per gene to measure its expression level. Individual probe signals can vary widely, which hampers proper interpretation. This variation can be caused by probes that do not pr
Externí odkaz:
https://doaj.org/article/971318f6b5734b7c85ec4614e1b1571d
Publikováno v:
BMC Genomics, Vol 8, Iss 1, p 78 (2007)
Abstract Background Predicting the function of newly discovered proteins by simply inspecting their amino acid sequence is one of the major challenges of post-genomic computational biology, especially when done without recourse to experimentation or
Externí odkaz:
https://doaj.org/article/a6af67b935d14ad2a14bf47c814bbd78