Multinational proficiency tests for EGFR exon 20 insertions reveal that the assay design matters.

Autor: Ihle MA; Institute of Pathology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Kerpener Str. 62, 50924, Cologne, Germany. michaela.ihle@uk-koeln.de., Heydt C; Institute of Pathology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Kerpener Str. 62, 50924, Cologne, Germany., Schultheis AM; Institute of Pathology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Kerpener Str. 62, 50924, Cologne, Germany., Stöhr R; Institute of Pathology, University Hospital Erlangen, Krankenhausstr. 8-10, 91054, Erlangen, Germany., Haller F; Institute of Pathology, University Hospital Erlangen, Krankenhausstr. 8-10, 91054, Erlangen, Germany., Herold S; Institute of Pathology, Hospital of the Technical University Dresden, Fetscherstr. 74, 01307, Dresden, Germany., Aust D; Institute of Pathology, Hospital of the Technical University Dresden, Fetscherstr. 74, 01307, Dresden, Germany., Dietmaier W; Institute of Pathology, University of Regensburg, Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Germany., Evert M; Institute of Pathology, University of Regensburg, Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Germany., Eszlinger M; Institute of Pathology, University Hospital Halle, Magdeburger Str. 14, 06112, Halle (Saale), Germany., Haak A; Institute of Pathology, University Hospital Halle, Magdeburger Str. 14, 06112, Halle (Saale), Germany., Laßmann S; Institute of Surgical Pathology, Medical Center Freiburg, Breisacherstr. 115a, 79106, Freiburg, Germany., Vorholt D; Janssen-Cilag GmbH, Johnson&Johnson Platz 1, 41470, Neuss, Germany., Breitenbücher F; Janssen-Cilag GmbH, Johnson&Johnson Platz 1, 41470, Neuss, Germany., Werner M; Institute of Surgical Pathology, Medical Center Freiburg, Breisacherstr. 115a, 79106, Freiburg, Germany., Streubel A; Institute of Tissue Diagnostics, MVZ at Helios Klinikum Emil Von Behring, Walterhöferstr. 11, 14165, Berlin, Germany., Mairinger T; Institute of Tissue Diagnostics, MVZ at Helios Klinikum Emil Von Behring, Walterhöferstr. 11, 14165, Berlin, Germany., Grassow-Narlik M; Quality Assurance Initiative Pathology (Qualitätssicherungs-Initiative Pathologie [QuIP®]), Reinhardtstr. 1, 10117, Berlin, Germany., Merkelbach-Bruse S; Institute of Pathology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Kerpener Str. 62, 50924, Cologne, Germany.

Publikováno v: Scientific reports [Sci Rep] 2024 Jun 06; Vol. 14 (1), pp. 13069. Date of Electronic Publication: 2024 Jun 06.

Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis.

Autor: Nothdurft S; Laboratory of Molecular Oncology, Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Thumser-Henner C; Laboratory of Molecular Oncology, Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Breitenbücher F; Laboratory of Molecular Oncology, Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Okimoto RA; Department of Medicine, University of California, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA., Dorsch M; Laboratory of Molecular Tumor Pathology, Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany., Opitz CA; DKTK Brain Cancer Metabolism Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital of Heidelberg, Heidelberg, Germany., Sadik A; DKTK Brain Cancer Metabolism Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Faculty of Bioscience, Heidelberg University, Heidelberg, Germany., Esser C; IUF-Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany., Hölzel M; Institute of Experimental Oncology, University Hospital Bonn, University of Bonn, Bonn, Germany., Asthana S; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA., Forster J; German Cancer Consortium (DKTK), Partner Site University Hospital Essen, Essen, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Beisser D; Department of Biodiversity, University Duisburg-Essen, Essen, Germany., Kalmbach S; Laboratory of Molecular Oncology, Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Grüner BM; Laboratory of Molecular Tumor Pathology, Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany.; German Cancer Consortium (DKTK), Partner Site University Hospital Essen, Essen, Germany., Bivona TG; Department of Medicine, University of California, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA., Schramm A; Laboratory of Molecular Oncology, Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany. Alexander.Schramm@uk-essen.de., Schuler M; Laboratory of Molecular Oncology, Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany.; German Cancer Consortium (DKTK), Partner Site University Hospital Essen, Essen, Germany.

Publikováno v: Oncogenesis [Oncogenesis] 2020 Nov 19; Vol. 9 (11), pp. 102. Date of Electronic Publication: 2020 Nov 19.

Drugs Targeting Sirtuin 2 Exhibit Broad-Spectrum Anti-Infective Activity.

Autor: Shenk, Thomas^1,2 (AUTHOR) tshenk@princeton.edu, Kulp III, John L.³ (AUTHOR) john.kulp@coniferpoint.com, Chiang, Lillian W.¹ (AUTHOR) lillian@evrysbio.com

Publikováno v: Pharmaceuticals (14248247). Oct2024, Vol. 17 Issue 10, p1298. 26p.

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