Zobrazeno 1 - 10
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pro vyhledávání: '"Brehm JH"'
Autor:
Irlbeck Dm, David M. Margolis, Sampey Gc, Brehm Jh, David Favre, Corbin D. Jones, Jean-Pierre Routy, Matt Kanke, Edward P. Browne, McAllister Ab, Nancie M. Archin, Ferris Rg, Richard M. Dunham
The leading strategy towards eradication of human immunodeficiency virus (HIV) infection is the depletion of viral reservoirs through reversal of viral latency, followed by clearance of persistently infected cells. To date, a latency reversing agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e25b341067d5ae71d5ff8f3fdca23a29
Akademický článek
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Autor:
Okoye AA; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America., Fromentin R; Centre de Recherche du CHUM, Montréal, Québec, Canada.; Department of Microbiology, Infectiology and Immunology, Université de Montréal, Montreal, Québec, Canada., Takata H; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America., Brehm JH; ViiV Healthcare, Research Triangle Park, North Carolina, United States of America., Fukazawa Y; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America., Randall B; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America., Pardons M; Centre de Recherche du CHUM, Montréal, Québec, Canada.; Department of Microbiology, Infectiology and Immunology, Université de Montréal, Montreal, Québec, Canada., Tai V; ViiV Healthcare, Research Triangle Park, North Carolina, United States of America., Tang J; ViiV Healthcare, Research Triangle Park, North Carolina, United States of America., Smedley J; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America., Axthelm M; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America., Lifson JD; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, Maryland, United States of America., Picker LJ; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America., Favre D; UNC HIV Cure Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; HIV Discovery Performance Unit, GlaxoSmithKline, Research Triangle Park, North Carolina, United States of America., Trautmann L; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America., Chomont N; Centre de Recherche du CHUM, Montréal, Québec, Canada.; Department of Microbiology, Infectiology and Immunology, Université de Montréal, Montreal, Québec, Canada.
Publikováno v:
PLoS pathogens [PLoS Pathog] 2022 Jan 18; Vol. 18 (1), pp. e1010245. Date of Electronic Publication: 2022 Jan 18 (Print Publication: 2022).
Autor:
Nixon CC; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Mavigner M; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Sampey GC; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; UNC HIV Cure Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Qura Therapeutics, Chapel Hill, NC, USA., Brooks AD; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Spagnuolo RA; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Irlbeck DM; Qura Therapeutics, Chapel Hill, NC, USA.; HIV Drug Discovery, ViiV Healthcare, Research Triangle Park, NC, USA., Mattingly C; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Ho PT; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Schoof N; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Cammon CG; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Tharp GK; Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA., Kanke M; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Wang Z; GlaxoSmithKline Research and Development, Collegeville, PA, USA., Cleary RA; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Upadhyay AA; Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA., De C; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Wills SR; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; UNC HIV Cure Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Qura Therapeutics, Chapel Hill, NC, USA., Falcinelli SD; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; UNC HIV Cure Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Galardi C; Qura Therapeutics, Chapel Hill, NC, USA.; HIV Drug Discovery, ViiV Healthcare, Research Triangle Park, NC, USA., Walum H; Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA., Schramm NJ; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Deutsch J; GlaxoSmithKline Research and Development, Collegeville, PA, USA., Lifson JD; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Fennessey CM; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Keele BF; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Jean S; Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA., Maguire S; GlaxoSmithKline Research and Development, Collegeville, PA, USA., Liao B; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China., Browne EP; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; UNC HIV Cure Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Ferris RG; Qura Therapeutics, Chapel Hill, NC, USA.; HIV Drug Discovery, ViiV Healthcare, Research Triangle Park, NC, USA., Brehm JH; Qura Therapeutics, Chapel Hill, NC, USA.; HIV Drug Discovery, ViiV Healthcare, Research Triangle Park, NC, USA., Favre D; Qura Therapeutics, Chapel Hill, NC, USA.; GlaxoSmithKline Research and Development, Collegeville, PA, USA., Vanderford TH; Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA., Bosinger SE; Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA., Jones CD; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Routy JP; Chronic Viral Infection Service, McGill University Health Centre, Montreal, Quebec, Canada.; Division of Hematology, McGill University Health Centre, Montreal, Quebec, Canada., Archin NM; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; UNC HIV Cure Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Margolis DM; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; UNC HIV Cure Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Qura Therapeutics, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Epidemiology, Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Wahl A; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Dunham RM; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. richard.m.dunham@viivhealthcare.com.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. richard.m.dunham@viivhealthcare.com.; UNC HIV Cure Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. richard.m.dunham@viivhealthcare.com.; Qura Therapeutics, Chapel Hill, NC, USA. richard.m.dunham@viivhealthcare.com.; HIV Drug Discovery, ViiV Healthcare, Research Triangle Park, NC, USA. richard.m.dunham@viivhealthcare.com., Silvestri G; Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA., Chahroudi A; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA. ann.m.chahroudi@emory.edu.; Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA. ann.m.chahroudi@emory.edu.; Emory + Children's Center for Childhood Infections and Vaccines, Atlanta, GA, USA. ann.m.chahroudi@emory.edu., Garcia JV; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. victor_garcia@med.unc.edu.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. victor_garcia@med.unc.edu.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. victor_garcia@med.unc.edu.
Publikováno v:
Nature [Nature] 2020 Feb; Vol. 578 (7793), pp. 160-165. Date of Electronic Publication: 2020 Jan 22.
Autor:
Kulpa DA; Department of Pediatrics, Emory University, Atlanta, Georgia, USA deanna.kulpa@emory.edu rafick.sekaly@case.edu., Talla A; Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA., Brehm JH; ViiV Healthcare, Research Triangle Park, North Carolina, USA., Ribeiro SP; Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA., Yuan S; Janssen Pharmaceuticals, Springhouse, Pennsylvania, USA., Bebin-Blackwell AG; University of Georgia, Athens, Georgia, USA., Miller M; Infectious Disease, Merck & Co., Inc., West Point, Pennsylvania, USA., Barnard R; Infectious Disease, Merck & Co., Inc., West Point, Pennsylvania, USA., Deeks SG; Department of Medicine, University of California, San Francisco, San Francisco, California, USA., Hazuda D; Infectious Disease, Merck & Co., Inc., West Point, Pennsylvania, USA., Chomont N; Centre de Recherche du CHUM, Montréal, Quebec, Canada.; Université de Montréal, Department of Microbiology, Infectiology, and Immunology, Montréal, Quebec, Canada., Sékaly RP; Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA deanna.kulpa@emory.edu rafick.sekaly@case.edu.
Publikováno v:
Journal of virology [J Virol] 2019 Nov 26; Vol. 93 (24). Date of Electronic Publication: 2019 Nov 26 (Print Publication: 2019).
Autor:
Gavegnano C; Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University, Atlanta, GA, United States of America., Brehm JH; Case Western Reserve University, Dept. of Pathology, Cleveland, OH, United States of America., Dupuy FP; Research Institute of the MUHC, Montréal, QC, Canada., Talla A; Case Western Reserve University, Dept. of Pathology, Cleveland, OH, United States of America., Ribeiro SP; Case Western Reserve University, Dept. of Pathology, Cleveland, OH, United States of America., Kulpa DA; Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University, Atlanta, GA, United States of America., Cameron C; Case Western Reserve University, Dept. of Pathology, Cleveland, OH, United States of America., Santos S; Unconditional Love, Melbourne, FL, United States of America., Hurwitz SJ; Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University, Atlanta, GA, United States of America., Marconi VC; Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, United States of America., Routy JP; Chronic Viral Illnesses Service Research Institute, Division of Hematology, McGill University Health Centre, Montréal, QC, Canada., Sabbagh L; Université de Montréal, Department of Microbiology, Infectiology, and Immunology, Montreal, QC, Canada., Schinazi RF; Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University, Atlanta, GA, United States of America., Sékaly RP; Case Western Reserve University, Dept. of Pathology, Cleveland, OH, United States of America.
Publikováno v:
PLoS pathogens [PLoS Pathog] 2017 Dec 21; Vol. 13 (12), pp. e1006740. Date of Electronic Publication: 2017 Dec 21 (Print Publication: 2017).
A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals.
Autor:
Procopio FA; Vaccine and Gene Therapy Institute Florida, Port St. Lucie, FL, USA., Fromentin R; Vaccine and Gene Therapy Institute Florida, Port St. Lucie, FL, USA., Kulpa DA; Vaccine and Gene Therapy Institute Florida, Port St. Lucie, FL, USA., Brehm JH; Vaccine and Gene Therapy Institute Florida, Port St. Lucie, FL, USA., Bebin AG; Vaccine and Gene Therapy Institute Florida, Port St. Lucie, FL, USA., Strain MC; University of California San Diego, La Jolla, California and Veterans Affairs San Diego Healthcare System, San Diego, CA, USA., Richman DD; University of California San Diego, La Jolla, California and Veterans Affairs San Diego Healthcare System, San Diego, CA, USA., O'Doherty U; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA., Palmer S; Centre for Virus Research, Westmead Millennium Institute, Westmead, Australia ; Sydney Medical School, University of Sydney, Sydney, Australia., Hecht FM; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Hoh R; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Barnard RJ; Infectious Disease, Merck Research Laboratories, West Point, PA, USA., Miller MD; Infectious Disease, Merck Research Laboratories, West Point, PA, USA., Hazuda DJ; Infectious Disease, Merck Research Laboratories, West Point, PA, USA., Deeks SG; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Sékaly RP; Vaccine and Gene Therapy Institute Florida, Port St. Lucie, FL, USA., Chomont N; Vaccine and Gene Therapy Institute Florida, Port St. Lucie, FL, USA.
Publikováno v:
EBioMedicine [EBioMedicine] 2015 Jun 27; Vol. 2 (8), pp. 874-83. Date of Electronic Publication: 2015 Jun 27 (Print Publication: 2015).
Autor:
Brehm JH; University of Pittsburgh School of Medicine, S818 Scaife Hall, 3550 Terrace St, Pittsburgh, Pennsylvania 15261, USA., Koontz DL, Wallis CL, Shutt KA, Sanne I, Wood R, McIntyre JA, Stevens WS, Sluis-Cremer N, Mellors JW
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2012 Sep; Vol. 55 (5), pp. 737-45. Date of Electronic Publication: 2012 May 22.
Autor:
Brehm JH; Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Scott Y, Koontz DL, Perry S, Hammer S, Katzenstein D, Mellors JW, Sluis-Cremer N
Publikováno v:
PloS one [PLoS One] 2012; Vol. 7 (2), pp. e31558. Date of Electronic Publication: 2012 Feb 21.