Zobrazeno 1 - 10
of 494
pro vyhledávání: '"Bregnhøj A"'
Autor:
Steven J. Roeters, Kris Strunge, Kasper B. Pedersen, Thaddeus W. Golbek, Mikkel Bregnhøj, Yuge Zhang, Yin Wang, Mingdong Dong, Janni Nielsen, Daniel E. Otzen, Birgit Schiøtt, Tobias Weidner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The amyloid aggregation of α-synuclein (αS), related to Parkinson’s disease, can be catalyzed by lipid membranes. Despite the importance of lipid surfaces, the 3D-structure and orientation of lipid-bound αS is still not known in detail.
Externí odkaz:
https://doaj.org/article/e2c70aa70bdf4978bba2517cd5c5812f
Publikováno v:
JEADV Clinical Practice, Vol 2, Iss 3, Pp 450-455 (2023)
Abstract Heat shock protein 90 (HSP90) is a chaperone protein belonging to the HSP family. HSP90 modulates clients by stabilising, folding, maturing, and tagging clients for proteasomal degradation. Several clients of HSP90 are involved in cancer dev
Externí odkaz:
https://doaj.org/article/3ad1443865d14773a678067fdd3d423e
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
BackgroundHeat shock protein 90 (HSP90) is an important chaperone supporting the function of many proinflammatory client proteins. Recent studies indicate HSP90 inhibition may be a novel mechanism of action for inflammatory skin diseases; however, th
Externí odkaz:
https://doaj.org/article/f467e1c9a7b047479ba2c01ba6bc2563
Akademický článek
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Akademický článek
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Autor:
Thomas Emmanuel, Borislav Ignatov, Trine Bertelsen, Thomas Litman, Morten Muhlig Nielsen, Mikkel Bo Brent, Toke Touborg, Anders Benjamin Rønsholdt, Annita Petersen, Mette Boye, Ida Kaaber, Daniel Sortebech, Dorte Lybæk, Torben Steiniche, Anne Bregnhøj, Liv Eidsmo, Lars Iversen, Claus Johansen
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6086 (2024)
Secukinumab and Dead Sea treatment result in clear skin for many psoriasis patients, through distinct mechanisms. However, recurrence in the same areas after treatments suggests the existence of a molecular scar. We aimed to compare the molecular and
Externí odkaz:
https://doaj.org/article/d735d84e244343d09c858131487c8d1a
Publikováno v:
Case Reports in Dermatology, Vol 15, Iss 1, Pp 26-30 (2023)
Prurigo pigmentosa (PP) is probably underdiagnosed due to lack of awareness. Previously, it was assumed that PP primarily affected Japanese females; however, more cases are reported worldwide, and the pathogenesis is still not completely understood.
Externí odkaz:
https://doaj.org/article/cd44d79f81754536b7e102c2877333a6
Autor:
Ben Abdallah, Hakim1 (AUTHOR) hba@clin.au.dk, Bregnhøj, Anne1 (AUTHOR), Iversen, Lars1 (AUTHOR), Johansen, Claus1 (AUTHOR)
Publikováno v:
International Journal of Molecular Sciences. Dec2023, Vol. 24 Issue 23, p17014. 15p.
Publikováno v:
JEADV Clinical Practice, Vol 1, Iss 4, Pp 307-316 (2022)
Abstract Psoriasis is a chronic inflammatory skin disease, in which molecular and cellular changes retain following clinical resolution of psoriatic lesions, a form of disease memory (‘molecular scar’) that may reestablish the psoriatic inflammat
Externí odkaz:
https://doaj.org/article/5ec9ce105bc042ff8bd8c393c8f67df1
Autor:
Knak Jensen, Svend J., Bregnhøj, Mikkel, Thøgersen, Jan, Nørnberg, Per, Nielsen, Anders Bodholt, Skibsted, Jørgen, Finster, Kai
Publikováno v:
In Chemical Physics Letters April 2023 816