The F-box protein FBXL-5 governs vitellogenesis and lipid homeostasis in C. elegans .

Autor: Breen PC; Integrative Program for Biological and Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, Unites States., Kanakanui KG; Integrative Program for Biological and Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, Unites States., Newman MA; Integrative Program for Biological and Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, Unites States., Dowen RH; Integrative Program for Biological and Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, Unites States.; Department of Cell Biology and Physiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, Unites States.; Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, Unites States.

Publikováno v: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2024 Jun 14; Vol. 12, pp. 1389077. Date of Electronic Publication: 2024 Jun 14 (Print Publication: 2024).

The TWK-26 potassium channel governs nutrient absorption in the C. elegans intestine.

Autor: Torzone SK, Breen PC, Cohen NR, Simmons KN, Dowen RH

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 07. Date of Electronic Publication: 2024 May 07.

Hypoxia-inducible factor induces cysteine dioxygenase and promotes cysteine homeostasis in Caenorhabditis elegans .

Autor: Warnhoff K; Pediatrics and Rare Diseases Group, Sanford Research, Sioux Falls, United States.; Department of Pediatrics, Sanford School of Medicine, University of South Dakota, Sioux Falls, United States., Bhattacharya S; Pediatrics and Rare Diseases Group, Sanford Research, Sioux Falls, United States., Snoozy J; Pediatrics and Rare Diseases Group, Sanford Research, Sioux Falls, United States., Breen PC; Department of Molecular Biology, Massachusetts General Hospital, Boston, United States., Ruvkun G; Department of Molecular Biology, Massachusetts General Hospital, Boston, United States.

Publikováno v: ELife [Elife] 2024 Feb 13; Vol. 12. Date of Electronic Publication: 2024 Feb 13.

Opposing action of the FLR-2 glycoprotein hormone and DRL-1/FLR-4 MAP kinases balance p38-mediated growth and lipid homeostasis in C. elegans.

Autor: Torzone SK; Integrative Program for Biological and Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Park AY; Integrative Program for Biological and Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Breen PC; Integrative Program for Biological and Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Cohen NR; Integrative Program for Biological and Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Dowen RH; Integrative Program for Biological and Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Department of Cell Biology and Physiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.

Publikováno v: PLoS biology [PLoS Biol] 2023 Sep 29; Vol. 21 (9), pp. e3002320. Date of Electronic Publication: 2023 Sep 29 (Print Publication: 2023).

Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression.

Autor: Lehrbach NJ; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Breen PC; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA., Ruvkun G; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. Electronic address: ruvkun@molbio.mgh.harvard.edu.

Publikováno v: Cell [Cell] 2019 Apr 18; Vol. 177 (3), pp. 737-750.e15.