Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Breda, Cullen"'
Publikováno v:
BJPsych Open, Vol 10, Pp S3-S3 (2024)
Aims Epidemiological studies have previously shown a link between cardiometabolic disease and severe mental illness. The extent and mechanisms behind this link are poorly understood currently but links to impairments in the stress response and cortis
Externí odkaz:
https://doaj.org/article/759e09384efa4046bac840d48b4d98f3
Autor:
Joey Ward, Laura M. Lyall, Breda Cullen, Rona J. Strawbridge, Xingxing Zhu, Ioana Stanciu, Alisha Aman, Claire L. Niedzwiedz, Jana Anderson, Mark E. S. Bailey, Donald M. Lyall, Jill P. Pell
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Happiness is a fundamental human affective trait, but its biological basis is not well understood. Using a novel approach, we construct LDpred-inf polygenic scores of a general happiness measure in 2 cohorts: the Adolescent Brain Cognitive D
Externí odkaz:
https://doaj.org/article/80fe9bf8ebab4344ac6435ca01993e32
Autor:
Niamh MacSweeney, Judith Allardyce, Amelia Edmondson-Stait, Xueyi Shen, Hannah Casey, Stella W.Y. Chan, Breda Cullen, Rebecca M. Reynolds, Sophia Frangou, Alex S.F. Kwong, Stephen M. Lawrie, Liana Romaniuk, Heather C. Whalley
Publikováno v:
Developmental Cognitive Neuroscience, Vol 60, Iss , Pp 101223- (2023)
Background: Earlier pubertal timing is associated with higher rates of depressive disorders in adolescence. Neuroimaging studies report brain structural associations with both pubertal timing and depression. However, whether brain structure mediates
Externí odkaz:
https://doaj.org/article/90bd096d94294c89b7c408528f84bd50
Autor:
Xingxing Zhu, Joey Ward, Breda Cullen, Donald M. Lyall, Rona J. Strawbridge, Laura M. Lyall, Daniel J. Smith
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Anhedonia is a core symptom of multiple psychiatric disorders and has been associated with alterations in brain structure. Genome-wide association studies suggest that anhedonia is heritable, with a polygenic architecture, but few studies ha
Externí odkaz:
https://doaj.org/article/9cc2fbfc954c4c5c94085397fdf1f3db
Autor:
Rona J. Strawbridge, Keira J. A. Johnston, Mark E. S. Bailey, Damiano Baldassarre, Breda Cullen, Per Eriksson, Ulf deFaire, Amy Ferguson, Bruna Gigante, Philippe Giral, Nicholas Graham, Anders Hamsten, Steve E. Humphries, Sudhir Kurl, Donald M. Lyall, Laura M. Lyall, Jill P. Pell, Matteo Pirro, Kai Savonen, Andries J. Smit, Elena Tremoli, Tomi-Pekka Tomainen, Fabrizio Veglia, Joey Ward, Bengt Sennblad, Daniel J. Smith
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Understanding why individuals with severe mental illness (Schizophrenia, Bipolar Disorder and Major Depressive Disorder) have increased risk of cardiometabolic disease (including obesity, type 2 diabetes and cardiovascular disease), and iden
Externí odkaz:
https://doaj.org/article/7e59d46ec2fd4250ae99b8ac5242f619
Autor:
Johannes H De Kock, Helen Ann Latham, Richard G Cowden, Breda Cullen, Katia Narzisi, Shaun Jerdan, Sarah-Anne Munoz, Stephen J Leslie, Andreas Stamatis, Jude Eze
Publikováno v:
JMIR Mental Health, Vol 9, Iss 4, p e34002 (2022)
BackgroundHealth and social care staff are at high risk of experiencing adverse mental health (MH) outcomes during the COVID-19 pandemic. Hence, there is a need to prioritize and identify ways to effectively support their psychological well-being (PW
Externí odkaz:
https://doaj.org/article/c58cf718812e4c11be83eddab637d7fb
Autor:
Johannes H. De Kock, Helen Ann Latham, Richard G. Cowden, Breda Cullen, Katia Narzisi, Shaun Jerdan, Sarah-Anne Muñoz, Stephen J. Leslie, Neil McNamara, Adam Boggon, Roger W. Humphry
Publikováno v:
BJPsych Open, Vol 8 (2022)
Background Health and social care workers (HSCWs) are at risk of experiencing adverse mental health outcomes (e.g. higher levels of anxiety and depression) because of the COVID-19 pandemic. This can have a detrimental effect on quality of care, the n
Externí odkaz:
https://doaj.org/article/164374b6d92d478389043274255feef5
Autor:
Alisha Aman, Eric A W Slob, Joey Ward, Breda Cullen, Nicholas Graham, Donald M Lyall, Naveed Sattar, Rona J Strawbridge
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0279381 (2022)
Prescription of PCSK9-inhibitors has increased in recent years but not much is known about its off-target effects. PCSK9-expression is evident in non-hepatic tissues, notably the brain, and genetic variation in the PCSK9 locus has recently been shown
Externí odkaz:
https://doaj.org/article/c4f6534f0ef64dc2b636c2ff58463ffc
Autor:
Michael Farquhar, Heather Whalley, Sharon Simpson, Breda Cullen, Mark Matthews, Judith Brown, Daniel Smith, Malcolm von Schantz, Giulia Gaggioni, Stella Chan, Daniela Gibbons, Alice Gregory, Joanna Inchley, Laura Lyall, Alyson O’Brien, Natasha Sangha, Manuel Spitschan, Cathy Wyse
Publikováno v:
BMJ Open Respiratory Research, Vol 8, Iss Suppl 1 (2021)
Externí odkaz:
https://doaj.org/article/e0356b2bad1146ad85e32bea1dc76e1e
Autor:
Rona J. Strawbridge, Joey Ward, Amy Ferguson, Nicholas Graham, Richard J. Shaw, Breda Cullen, Robert Pearsall, Laura M. Lyall, Keira J.A. Johnston, Claire L. Niedzwiedz, Jill P. Pell, Daniel Mackay, Julie Langan Martin, Donald M. Lyall, Mark E.S. Bailey, Daniel J. Smith
Publikováno v:
EBioMedicine, Vol 41, Iss , Pp 517-525 (2019)
Background: Suicide is a major issue for global public health. Suicidality describes a broad spectrum of thoughts and behaviours, some of which are common in the general population. Although suicide results from a complex interaction of multiple soci
Externí odkaz:
https://doaj.org/article/4f2c70fc50b2469c8422fb03da4fd838