Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Brecht Egle"'
Publikováno v:
Organic Process Research & Development. 25:2438-2441
We performed a systematic investigation of the conditions causing or preventing self-ignition of spent palladium on a carbon catalyst after hydrogenation reactions. The solvent used for hydrogenati...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0a4a0636d27a892070ab927cdd08058
https://doi.org/10.1021/acs.oprd.1c00190
https://doi.org/10.1021/acs.oprd.1c00190
Autor:
Philippe Gilles, Luc Van Meervelt, Cedrick Veryser, Brecht Egle, Seger Van Mileghem, Wim M. De Borggraeve
Publikováno v:
Organic & Biomolecular Chemistry. 15:373-378
The design and synthesis of oligoamide α-helix peptidomimetics is reported. The oligoamide type systems are prepared in a modular fashion by coupling the monomers using palladium-catalyzed carbonylation chemistry. This enabled us to use substrates w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41169828141d563637d0eb7c051c94c
https://doi.org/10.1039/c6ob02358d
https://doi.org/10.1039/c6ob02358d
Publikováno v:
Reaction Chemistry & Engineering. 1:142-146
Three low-cost standard lab chemicals, formic acid, mesyl chloride and triethylamine, were used for instant carbon monoxide (CO) generation at room temperature. Subsequently this gas was implemented in palladium-catalysed aminocarbonylation chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5387c541b0041665d7ac78a9a7e90873
https://doi.org/10.1039/c6re00006a
https://doi.org/10.1039/c6re00006a
Autor:
Nerea Alonso, Angel Díaz-Ortiz, Juan M. de Muñoz, Wim M. De Borggraeve, Antonio de la Hoz, Brecht Egle, Jesús Alcázar
Publikováno v:
Journal of Flow Chemistry. 4:22-25
The first example of an alkyl–aryl Negishi coupling in a practical, sustainable, and high-yielding process using a silica-supported catalyst in flow is described. Excellent conversions and good functional group compatibility were obtained under ver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::065b8ac8f6702f55497cc4c287f50c8a
https://doi.org/10.1556/jfc-d-13-00009
https://doi.org/10.1556/jfc-d-13-00009
Autor:
Angel Díaz-Ortiz, Wim M. De Borggraeve, Jesús Alcázar, Nerea Alonso, Antonio de la Hoz, Johannes L. Vrijdag, Brecht Egle, Juan de M. Muñoz
© 2014 Akadémiai Kiadó. The first continuous flow carbonylation reaction using aryl formates as CO precursor is reported. The reaction is practical, scalable and high yielding. The use of a flow protocol safely allows expanding the scope to activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326c64ac83c6b43fed8cbb3bc847b826
https://lirias.kuleuven.be/handle/123456789/446945
https://lirias.kuleuven.be/handle/123456789/446945
Autor:
Mieke Trekels, Tom Venken, Wim M. De Borggraeve, Rani Alphonsa Jose, Aline Vandenbulcke, Marc De Maeyer, Katleen Broos, Jonas Demeulemeester, Nele Vandeputte, Hans Deckmyn, Brecht Egle
Publikováno v:
The Journal of biological chemistry. 287(12)
The von Willebrand factor (VWF) A1-glycoprotein (GP) Ibα interaction is of major importance during thrombosis mainly at sites of high shear stress. Inhibitors of this interaction prevent platelet-dependent thrombus formation in vivo, without major b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c2825758c08afeae2f93117e123231
https://pubmed.ncbi.nlm.nih.gov/22232560
https://pubmed.ncbi.nlm.nih.gov/22232560
Autor:
Brecht Egle, Kam Y. J. Zhang, Wim M. De Borggraeve, Arjen J. Jakobi, Arnout Voet, Gilles Bruylants, Marc De Maeyer, Rani Alphonsa Jose, Katleen Broos, Hans Deckmyn
Publikováno v:
Chemical Communications. 48:11349
An integrated approach comprising STD NMR screening, pharmacophore based analogue selection and a bioassay is presented for the discovery of a stabilizer of the clinically relevant VWF-GPIbα protein-protein interaction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9aedd7a5b41f61e0bf5390fe50fd50e
https://doi.org/10.1039/c2cc35269a
https://doi.org/10.1039/c2cc35269a