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High-Content Small Molecule Screen Identifies a Novel Compound That Restores AP-4-Dependent Protein Trafficking in Neuronal Models of AP-4-Associated Hereditary Spastic Paraplegia.

Autor: Saffari A; Boston Children's Hospital, Harvard Medical School., Brechmann B; Boston Children's Hospital, Harvard Medical School., Boeger C; Boston Children's Hospital, Harvard Medical School., Saber WA; Boston Children's Hospital/Harvard Medical School., Jumo H, Whye D; Boston Children's Hospital, Harvard Medical School., Wood D; Boston Children's Hospital, Harvard Medical School., Wahlster L; Boston Children's Hospital, Harvard Medical School., Alecu J; Boston Children's Hospital, Harvard Medical School., Ziegler M; Harvard Medical School., Scheffold M; Boston Children's Hospital, Harvard Medical School., Winden K; Boston Children's Hospital., Hubbs J; Boston Children's Hospital., Buttermore E; Boston Children's Hospital., Barrett L; Boston Children's Hospital., Borner G; Max Planck Institute of Biochemistry., Davies A; Max Planck Institute of Biochemistry., Sahin M; Boston Children's Hospital., Ebrahimi-Fakhari D; Boston Children's Hospital, Harvard Medical School.

Publikováno v: Research square [Res Sq] 2023 Jun 12. Date of Electronic Publication: 2023 Jun 12.