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Akademický článek

Data Management 101 for drug developers: A peek behind the curtain

Autor: Bryan Oronsky, Erica Burbano, Meaghan Stirn, Joanne Brechlin, Nacer Abrouk, Scott Caroen, Angelique Coyle, Jeannie Williams, Pedro Cabrales, Tony R. Reid

Publikováno v: Clinical and Translational Science, Vol 16, Iss 9, Pp 1497-1509 (2023)

Abstract In drug development a frequently used phrase is “data‐driven”. Just as high‐test gas fuels a car, so drug development “runs on” high‐quality data; hence, good data management practices, which involve case report form design, da

Externí odkaz: https://doaj.org/article/70093a437cb04467ae0f11efeab45dfb

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Akademický článek

An updated checklist of the wild silkmoths (Lepidoptera, Saturniidae) of Colombia

Autor: Lorenzo Comoglio, Ronald Brechlin

Publikováno v: ZooKeys, Vol 1178, Iss , Pp 191-264 (2023)

In recent years, the study of wild silkmoths (Lepidoptera: Saturniidae) has increased exponentially due to the intense sampling effort and the use of molecular evidence for species delimitation, which led to the description of numerous new taxa espec

Externí odkaz: https://doaj.org/article/5627747d390d44f8b949b38c09af215b

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Akademický článek

Upregulation of CRABP1 in human neuroblastoma cells overproducing the Alzheimer-typical Aβ42 reduces their differentiation potential

Autor: Weninger Annette, Knyazev Yuri, Jahn Olaf, Brechlin Peter, Uhrig Markus, Busia Laura, Honarnejad Kamran, Otto Markus, Hartmann Tobias

Publikováno v: BMC Medicine, Vol 6, Iss 1, p 38 (2008)

Abstract Background Alzheimer's disease (AD) is characterized by neurodegeneration and changes in cellular processes, including neurogenesis. Proteolytic processing of the amyloid precursor protein (APP) plays a central role in AD. Owing to varying A

Externí odkaz: https://doaj.org/article/e8cea58563c04c72990c833c7ef55ef7

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