Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Breast epithelial cell"'
Autor:
Guiju Cai, Yuejiao Wang, Tahiri Houda, Chun Yang, Lijuan Wang, Muqing Gu, Alfred Mueck, Stephane Croteau, Xiangyan Ruan, Pierre Hardy
Publikováno v:
Translational Oncology, Vol 14, Iss 6, Pp 101068- (2021)
Background: Research suggests that hormone replacement therapy may increase the risk of breast cancer, and progestins such as norethisterone (NET) play a key role in this phenomenon. We have demonstrated that microRNA-181a (miR-181a) suppresses NET-p
Externí odkaz:
https://doaj.org/article/a6dd92f65d5242c2a9fb3d39964ec61d
Autor:
Tuba Korkmaz, Fatih Aygenli, Handan Emisoglu, Gozde Ozcelik, Asena Canturk, Secil Yilmaz, Nuri Ozturk
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract The circadian clock confers daily rhythmicity on many biochemical and physiological functions and its disruption is associated with increased risks of developing obesity, diabetes, heart disease and cancer. Although, there are studies on the
Externí odkaz:
https://doaj.org/article/6325aed49fa749149050d389034e30d3
Autor:
Muqing Gu, Tahiri Houda, Lijuan Wang, Yuejiao Wang, Pierre Hardy, Stéphane Croteau, Alfred O. Mueck, Xiangyan Ruan, Guiju Cai, Chun Yang
Publikováno v:
Translational Oncology, Vol 14, Iss 6, Pp 101068-(2021)
Translational Oncology
Translational Oncology
Highlight • NET possesses pro-tumorigenesis effect on human breast epithelial MCF10A cells. • NET upregulates PGRMC1/EGFR and suppresses PTEN expression. • NET stimulates the PI3K/Akt/mTOR signal pathway. • Overexpression of miR-181a abrogate
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 5, p 1244 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 5
International Journal of Molecular Sciences
Volume 20
Issue 5
The anthracycline antibiotic doxorubicin is commonly used antineoplastic drug in breast cancer treatment. Like most chemotherapy, doxorubicin does not selectively target tumorigenic cells with high proliferation rate and often causes serve side effec
Akademický článek
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Publikováno v:
Journal of Visualized Experiments.
The wound-healing assay is efficient and one of the most economical ways to study cell migration in vitro. Conventionally, images are taken at the beginning and end of an experiment using a phase-contrast microscope, and the migration abilities of ce
Publikováno v:
Acta Biochimica et Biophysica Sinica. 47:53-59
Accumulated evidence suggests that the Hippo signaling pathway plays crucial roles in mammary gland development and breast cancer. Key components of the Hippo pathway regulate breast epithelial cell proliferation, migration, invasion, and stemness. A
Akademický článek
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Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 10:E121-E131
In the present study, the effects of air-flow impedance electrospinning and air-flow rates on silk-based scaffolds for biological tissues were investigated. First, the properties of scaffolds obtained from 7% and 12% silk concentrations were defined.
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:1462-1466
Some polyoxometalate (POM) clusters have demonstrated attractive anticancer properties. Unfortunately, their cytotoxicity upon normal cell is one of fateful side effects obstructing their further clinic application as inorganic drugs. In this communi