Zobrazeno 1 - 10
of 841
pro vyhledávání: '"Breast cancer subtypes"'
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-13 (2024)
Abstract Background Menopausal hormone therapy (MHT) is associated with an increased risk of postmenopausal breast cancer, predominantly the luminal A-like subtype. The impact of MHT on deaths from breast cancer subtypes is less understood. This stud
Externí odkaz:
https://doaj.org/article/aa2954ae3ac342ec9121d32ffe94b88d
Autor:
Esther M. John, Jocelyn Koo, Amanda I. Phipps, Teri A. Longacre, Allison W. Kurian, Sue A. Ingles, Anna H. Wu, Lisa M. Hines
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-29 (2024)
Abstract Background Associations between reproductive factors and risk of breast cancer differ by subtype defined by joint estrogen receptor (ER), progesterone receptor (PR), and HER2 expression status. Racial and ethnic differences in the incidence
Externí odkaz:
https://doaj.org/article/17c638024b9b4f8abff20d138467095e
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background Classifying breast cancer subtypes is crucial for clinical diagnosis and treatment. However, the early symptoms of breast cancer may not be apparent. Rapid advances in high-throughput sequencing technology have led to generating l
Externí odkaz:
https://doaj.org/article/a11e095a40ec426d8ff9efa446064402
Autor:
Leandro Y. S. Okimoto, Rayol Mendonca-Neto, Fabíola G. Nakamura, Eduardo F. Nakamura, David Fenyö, Claudio T. Silva
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-22 (2024)
Abstract Background In recent years, researchers have made significant strides in understanding the heterogeneity of breast cancer and its various subtypes. However, the wealth of genomic and proteomic data available today necessitates efficient fram
Externí odkaz:
https://doaj.org/article/bba6169bf35f424e8bdadd9761e3f47f
Autor:
Jong-Ho Cheun, Youngji Kwak, Eunhye Kang, Ji-Jung Jung, Hong-Kyu Kim, Han-Byoel Lee, Kyung-Hun Lee, Hyeong-Gon Moon, Ki-Tae Hwang, Yeon Hee Park, Jeong Eon Lee, Wonshik Han
Publikováno v:
Breast, Vol 78, Iss , Pp 103828- (2024)
Background: Neoadjuvant chemotherapy (NACT) for early-stage breast cancer is associated with an increased risk of locoregional recurrence (LRR). We investigated whether the risk of LRR after NACT varies across tumor subtypes. Methods: We retrospectiv
Externí odkaz:
https://doaj.org/article/69e72bca1dc84536b9d19caab0c3937b
Autor:
Stefan Prekovic, Theofilos Chalkiadakis, Merel Roest, Daniel Roden, Catrin Lutz, Karianne Schuurman, Mark Opdam, Liesbeth Hoekman, Nina Abbott, Tanja Tesselaar, Maliha Wajahat, Amy R Dwyer, Isabel Mayayo‐Peralta, Gabriela Gomez, Maarten Altelaar, Roderick Beijersbergen, Balázs Győrffy, Leonie Young, Sabine Linn, Jos Jonkers, Wayne Tilley, Theresa Hickey, Damir Vareslija, Alexander Swarbrick, Wilbert Zwart
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-17 (2023)
Abstract Glucocorticoid receptor (GR) is a transcription factor that plays a crucial role in cancer biology. In this study, we utilized an in silico‐designed GR activity signature to demonstrate that GR relates to the proliferative capacity of nume
Externí odkaz:
https://doaj.org/article/7f89e9b972df425581429cdb0b5d1a09
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-14 (2023)
Abstract Background Body fatness is a dynamic exposure throughout life. To provide more insight into the association between body mass index (BMI) and postmenopausal breast cancer, we aimed to examine the age at onset, duration, intensity, and trajec
Externí odkaz:
https://doaj.org/article/ff8075eceda64afb97942340fe701464
Autor:
Slavica Janeva, Ellen Krabbe, Toshima Z. Parris, Salmir Nasic, Marie Sundquist, Per Karlsson, Riccardo A. Audisio, Roger Olofsson Bagge, Anikó Kovács
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-11 (2023)
Abstract Background When ipsilateral multifocal primary breast cancer (IMBC) is detected, standard routine is to evaluate the largest tumor with immunohistochemistry (IHC). As all foci are not routinely characterized, many patients may not receive op
Externí odkaz:
https://doaj.org/article/41153ac5c52c4a31bf5f1cb43f65d9f0
Publikováno v:
Applied Sciences, Vol 14, Iss 7, p 2728 (2024)
The precise classification of breast cancer subtypes is crucial for clinical diagnosis and treatment, yet early symptoms are often subtle. The use of multi-omics data from high-throughput sequencing can improve the classification accuracy. However, m
Externí odkaz:
https://doaj.org/article/cf06505d91dd4e1f833dc308bdf27eb9
Autor:
Suk Jun Lee, Jieon Go, Byung Soo Ahn, Jee Hyun Ahn, Jee Ye Kim, Hyung Seok Park, Seung Il Kim, Byeong-Woo Park, Seho Park
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
PurposeLymphovascular invasion (LVI) is a well-known poor prognostic factor for early breast cancer. However, the effect of LVI on breast cancer subtype and node status remains unknown. In this study, we aimed to evaluate the clinical significance of
Externí odkaz:
https://doaj.org/article/ce98204aab514da6a5cd88dd0b869287