Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Breanna Wallace"'
Autor:
Timothy Hoey, Austin Gurney, John Lewicki, Ann M. Kapoun, Chun Zhang, Min Wang, Breanna Wallace, Tracy Tang, Jalpa Shah, Aaron Sato, Rene Meisner, William R. Henner, Belinda Cancilla, Jennifer Cain, Christopher Bond, Fumiko Axelrod, Marcus M. Fischer, Wan-Ching Yen
Table S1: OMP-59R5 binding data as assessed by surface plasmon resonance (Biacore); Table S2. Histopathology of human pancreatic tumors; Table S3. Effect of anti-Notch2/3 antibody OMP-59R5 in combination with gemcitabine on growth of pancreatic xenog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf498724cd8f0c5646ff30984a2c9c4
https://doi.org/10.1158/1078-0432.22458093
https://doi.org/10.1158/1078-0432.22458093
Autor:
Timothy Hoey, Austin Gurney, John Lewicki, Ann M. Kapoun, Chun Zhang, Min Wang, Breanna Wallace, Tracy Tang, Jalpa Shah, Aaron Sato, Rene Meisner, William R. Henner, Belinda Cancilla, Jennifer Cain, Christopher Bond, Fumiko Axelrod, Marcus M. Fischer, Wan-Ching Yen
Purpose: The Notch pathway plays an important role in both stem cell biology and cancer. Dysregulation of Notch signaling has been reported in several human tumor types. In this report, we describe the development of an antibody, OMP-59R5 (tarextumab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f473b99c67334f0815470d792e6624
https://doi.org/10.1158/1078-0432.c.6523824.v1
https://doi.org/10.1158/1078-0432.c.6523824.v1
Autor:
Timothy Hoey, Austin Gurney, John Lewicki, Ann M. Kapoun, Chun Zhang, Min Wang, Breanna Wallace, Tracy Tang, Jalpa Shah, Aaron Sato, Rene Meisner, William R. Henner, Belinda Cancilla, Jennifer Cain, Christopher Bond, Fumiko Axelrod, Marcus M. Fischer, Wan-Ching Yen
Figure S1A. Binding affinities of OMP-59R5 to human (h) Notch1-4 receptors; Figure S1B. Alignment of the EGF repeats 10-15 of Notch2 and 9-14 of Notch3 from human (h), cynomolgus monkey (cyno), and mouse (m); Figure S2. Human NOTCH1, NOTCH2 and NOTCH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f59c2b422fb81b4b510586fa10a689b
https://doi.org/10.1158/1078-0432.22458096.v1
https://doi.org/10.1158/1078-0432.22458096.v1
Autor:
John Lewicki, Jalpa Shaw, Tim Hoey, Marcus Fischer, Fumiko Takada Axelrod, Wan-Ching Yen, Christopher J. Bond, Austin L. Gurney, Jakob Dupont, Belinda Cancilla, Min Wang, Aaron K. Sato, Chun Zhang, Breanna Wallace, Lei Zhou, Jennifer Cain, Rene Meisner, Ann M. Kapoun, Randall Henner, Tracy Tang
Publikováno v:
Clinical Cancer Research. 22:A41-A41
Accumulating evidence has suggested that tumors may arise and grow as a result of the formation of a subset cell population termed cancer stem cells (CSC) or tumor initiating cells. Several research reports have indicated that CSCs are relatively res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a27437dbb392d89d6e80e0d7b837b7a
https://doi.org/10.1158/1557-3265.pdx16-a41
https://doi.org/10.1158/1557-3265.pdx16-a41
Autor:
Christopher Murriel, Austin L. Gurney, Breanna Wallace, John Lewicki, Jalpa Shah, Jennifer Cain, Tim Hoey, Aaron K. Sato, Jie Wei, Ann M. Kapoun, Tracy Tang, Cancilla Belinda, Min Wang
Publikováno v:
Clinical Cancer Research. 21:A33-A33
Cancer stem cells (CSCs) have been identified as the small subpopulation of cells in many cancers and are thought to be responsible for cancer initiation, progression, metastasis, recurrence and drug resistance. The NOTCH pathway, comprised of ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a14cef99e05fc9dacd5e72eef2357f2
https://doi.org/10.1158/1557-3265.pms14-a33
https://doi.org/10.1158/1557-3265.pms14-a33
Autor:
Gretchen Argast, Rene Meisner, Yu-Wang Liu, Tim Hoey, Breanna Wallace, Min Wang, Ann M. Kapoun
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 81:358
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ac5940b29091f1df54c5a4d6b13ea7d
https://doi.org/10.1016/j.vascn.2016.02.076
https://doi.org/10.1016/j.vascn.2016.02.076
Autor:
Tracy Tang, Jalpa Shah, Jennifer Cain, Aaron K. Sato, Ann M. Kapoun, Belinda Cancilla, Breanna Wallace, Min Wang, Tim Hoey, Jie Wei, Austin L. Gurney, John Lewicki, Chris Muriel
Publikováno v:
Cancer Research. 73:213-213
The Notch signaling pathway, driven by four Notch family receptors (NOTCH1-4) and five canonical Notch ligands (DLL1, DLL3, DLL4, JAG1, and JAG2) in humans, critically regulates key functions during embryonic development as well as stem cell maintena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::610c0f674d591ce6b7ca8a5859d3680d
https://doi.org/10.1158/1538-7445.am2013-213
https://doi.org/10.1158/1538-7445.am2013-213
Publikováno v:
FASEB Journal; Apr2014 Supplement S1, Vol. 28, pN.PAG-N.PAG, 1p
Publikováno v:
Business Wire (English). 04/09/2013.
Publikováno v:
Business Wire (English). 04/02/2013.