Cigarette smoke directly impairs skeletal muscle function through capillary regression and altered myofibre calcium kinetics in mice

Autor: Masahiro Yamaguchi, Ellen C. Breen, Breanna M. Trisko, Jason Matthew Jackson, Frederico L. Lima‐Rosa, Leonardo Nogueira, Helena Lund‐Palau

Publikováno v: The Journal of Physiology. 596:2901-2916

KEY POINTS:Cigarette smoke components directly alter muscle fatigue resistance and intracellular muscle fibre Ca2+ handling independent of a change in lung structure. Changes in muscle vascular structure are associated with a depletion of satellite c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ba99d3e15e3c3bd5faccd8b2fbe7c681
https://doi.org/10.1113/jp275888

Skeletal myofiber VEGF regulates contraction-induced perfusion and exercise capacity but not muscle capillarity in adult mice

Autor: Ellen C. Breen, Peter D. Wagner, Breanna M. Trisko, Kechun Tang, Hamid Delavar, D.E. Goldberg, Amy E. Knapp, Michael C. Hogan

Publikováno v: American journal of physiology. Regulatory, integrative and comparative physiology, vol 311, iss 1
Knapp, AE; Goldberg, D; Delavar, H; Trisko, BM; Tang, K; Hogan, MC; et al.(2016). Skeletal myofiber VEGF regulates contraction-induced perfusion and exercise capacity but not muscle capillarity in adult mice. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 311(1), R192-R199. doi: 10.1152/ajpregu.00533.2015. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/8pr0b3hz

A single bout of exhaustive exercise signals expression of vascular endothelial growth factor (VEGF) in the exercising muscle. Previous studies have reported that mice with life-long deletion of skeletal myofiber VEGF have fewer capillaries and a sev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ed235513e052be86bf10731c62f46b
https://escholarship.org/uc/item/8pr0b3hz

Cigarette smoke impairs the in situ fatigue resistance of locomotor skeletal muscle in mice (1102.18)

Autor: Ellen C. Breen, Breanna M. Trisko, Peter D. Wagner, Leonardo Nogueira

Publikováno v: The FASEB Journal. 28

Muscle dysfunction is thought to contribute to exercise intolerance in smokers with COPD. In this study, cigarette smoke (CS) was hypothesized to impair skeletal muscle fatigue resistance. To test ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9dbad2a6c08b0c04a78bf525266820f
https://doi.org/10.1096/fasebj.28.1_supplement.1102.18