Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Breanna Ford"'
Autor:
Candice B. Herber, William C. Krause, Liping Wang, James R. Bayrer, Alfred Li, Matthew Schmitz, Aaron Fields, Breanna Ford, Zhi Zhang, Michelle S. Reid, Daniel K. Nomura, Robert A. Nissenson, Stephanie M. Correa, Holly A. Ingraham
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Estrogen promotes negative energy balance and preserves skeletal physiology. Here the authors show that loss of estrogen signalling after ablating estrogen receptor alpha (ERa) in specific hypothalamic neuronal populations leads to a marked sex-depen
Externí odkaz:
https://doaj.org/article/e716ce14ed5d4a069d7f3a182f6e641a
Autor:
Michael Zhou, Breanna Ford, Douglas Lee, Gwen Tindula, Karen Huen, Vy Tran, Asa Bradman, Robert Gunier, Brenda Eskenazi, Daniel K. Nomura, Nina Holland
Publikováno v:
Frontiers in Public Health, Vol 6 (2018)
Phthalates are known endocrine disruptors and found in almost all people with several associated adverse health outcomes reported in humans and animal models. Limited data are available on the relationship between exposure to endocrine disrupting che
Externí odkaz:
https://doaj.org/article/ca79af8db4a04473b48dfe033ba989a0
Autor:
Valerie M. Weaver, Andrew S. Moore, Danielle L. Swaney, Jonathon M. Muncie, Andrew Dillin, Alexander R. Dunn, Carlos Garzon-Coral, Kuei-Ho Chen, Breanna Ford, Catherine Schneider, Joseph R. Daniele, Hao Shao, Marc Hellerstein, Sagar S. Manoli, Phillip A. Frankino, Daniel K. Nomura, Jason E. Gestwicki, Kevin M. Tharp, Gregory M. Ku, Greg A. Timblin, Nevan J. Krogan, Karou Saijo, Connor Stashko, Alicia L. Richards, Ryo Higuchi-Sanabria
Publikováno v:
Cell Metab
Cell metabolism, vol 33, iss 7
Cell metabolism, vol 33, iss 7
Mitochondria control eukaryotic cell fate by producing the energy needed to support life and the signals required to execute programmed cell death. The biochemical milieu is known to affect mitochondrial function and contribute to the dysfunctional m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d282d1f17247429a757bdd49f294f249
https://europepmc.org/articles/PMC8266765/
https://europepmc.org/articles/PMC8266765/
Autor:
Carl C. Ward, James A. Olzmann, Roberto Zoncu, Charles A. Berdan, Hijai R. Shin, Clive Yik-Sham Chung, Daniel K. Nomura, Breanna Ford
Publikováno v:
Nature chemical biology, vol 15, iss 8
Nature chemical biology
Nature chemical biology
Autophagy is a lysosomal degradation pathway that eliminates aggregated proteins and damaged organelles to maintain cellular homeostasis. A major route for activating autophagy involves inhibition of the mTORC1 kinase, but current mTORC1-targeting co
Autor:
Zhi Zhang, Daniel K. Nomura, Breanna Ford, Michelle S. Reid, James R. Bayrer, Matthew T. Schmitz, Candice B. Herber, William C. Krause, Liping Wang, Alfred Li, Aaron J. Fields, Robert A. Nissenson, Holly A. Ingraham, Stephanie M. Correa
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications, vol 10, iss 1
Nature Communications
Nature Communications, vol 10, iss 1
Central estrogen signaling coordinates energy expenditure, reproduction, and in concert with peripheral estrogen impacts skeletal homeostasis in females. Here, we ablate estrogen receptor alpha (ERα) in the medial basal hypothalamus and find a robus
Autor:
Andreas Stahl, Janet M. Winchenster, Stella Zhu, Jerome Wang, Johanna ten Hoeve, Kevin M. Tharp, Greg A. Timblin, Shannon K. Louie, Rida I. Khan, Daniel K. Nomura, Anthony T. Iavarone, Kaoru Saijo, Breanna Ford
Macrophages generate mitochondrial reactive oxygen and electrophilic species (mtROS, mtRES) as antimicrobials during Toll-like receptor (TLR)-dependent inflammatory responses. Whether mitochondrial stress caused by these molecules impacts macrophage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87ab4baf899bc5c39b08e0ff38032333
https://doi.org/10.1101/2020.10.20.347443
https://doi.org/10.1101/2020.10.20.347443
Autor:
Stella Zhu, Kevin M. Tharp, Kaoru Saijo, Breanna Ford, Rida I. Khan, Daniel K. Nomura, Johanna ten Hoeve, Shannon K. Louie, Anthony T. Iavarone, Janet M. Winchester, Greg A. Timblin, Andreas Stahl, Jerome Wang
Publikováno v:
Nature metabolism
Macrophages generate mitochondrial reactive oxygen species and mitochondrial reactive electrophilic species as antimicrobials during Toll-like receptor (TLR)-dependent inflammatory responses. Whether mitochondrial stress caused by these molecules imp
Autor:
Joseph M. Hendricks, Breanna Ford, James A. Olzmann, Thomas J. Maimone, Roberto Zoncu, Zhipeng Li, Peter H. Tang, Bingqi Tong, Melissa A. Roberts, Leslie Magtanong, Daniel K. Nomura, Michael C. Bassik, Scott J. Dixon, Kirill Bersuker
Publikováno v:
Nature, vol 575, iss 7784
Ferroptosis is a form of regulated cell death that is caused by the iron-dependent peroxidation of lipids1,2. The glutathione-dependent lipid hydroperoxidase glutathione peroxidase 4 (GPX4) prevents ferroptosis by converting lipid hydroperoxides into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::592cc6c7a67cba3c2c90a30abd576d9e
https://escholarship.org/uc/item/24j373dc
https://escholarship.org/uc/item/24j373dc
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 10
Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 10
Significance Phenols are common anthropogenic and natural chemicals that contaminate drinking water sources. To reduce exposure to these compounds, hydroxyl radicals are often used as chemical oxidants during water treatment. Although this treatment
Autor:
Rebecca Heald, Rachael Acker, Daniel K. Nomura, Ila van Kruijsbergen, Maiko Kitaoka, Georgios Georgiou, Romain Gibeaux, Breanna Ford, Edward M. Marcotte, Taejoon Kwon, Gert Jan C. Veenstra
Publikováno v:
Nature
Nature, Nature Publishing Group, 2018, 553 (7688), pp.337-341. ⟨10.1038/nature25188⟩
Nature, 553, 7688, pp. 337-356
Nature, vol 553, iss 7688
Nature, 553, 337-356
Nature, Nature Publishing Group, 2018, 553 (7688), pp.337-341. ⟨10.1038/nature25188⟩
Nature, 553, 7688, pp. 337-356
Nature, vol 553, iss 7688
Nature, 553, 337-356
Hybridization of eggs and sperm from closely related species can give rise to genetic diversity, or can lead to embryo inviability owing to incompatibility. Although central to evolution, the cellular and molecular mechanisms underlying post-zygotic