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High-throughput single-cell transcriptomics on organoids

Autor: Brazovskaja, Agnieska, Treutlein, Barbara, Camp, J Gray

Publikováno v: In Current Opinion in Biotechnology February 2019 55:167-171

CSS: cluster similarity spectrum integration of single-cell genomics data

Autor: He, Zhisong, Brazovskaja, Agnieska, Ebert, Sebastian, Camp, J. Gray, Treutlein, Barbara

Publikováno v: Genome Biology
Genome Biology, Vol 21, Iss 1, Pp 1-21 (2020)
Genome Biology, 21 (1)

It is a major challenge to integrate single-cell sequencing data across experiments, conditions, batches, time points, and other technical considerations. New computational methods are required that can integrate samples while simultaneously preservi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b319d0983559dd97f93afb311f917a

High-throughput single-cell transcriptomics on human development and regeneration

Autor: Brazovskaja, Agnieška

Heterogeneous human tissues are built from millions of cells and each single cell has its individual role during tissue homeostasis. High-throughput single-cell transcriptomics, a technology established less than 10 years ago, has been used to isolat

Externí odkaz: https://ul.qucosa.de/id/qucosa%3A84220
https://ul.qucosa.de/api/qucosa%3A84220/attachment/ATT-0/

Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program

Autor: Therese Riedemann, Sven Falk, Barbara Treutlein, J. Gray Camp, Tobias Gerber, Andrej Smiyakin, Magdalena Götz, Christian Schichor, Angela Garding, Agnieska Brazovskaja, Vijay K. Tiwari, Abhijeet Pataskar, Wenqiang Fan, Benedikt Berninger, Malgorzata Gac-Santel, Marisa Karow, Jorge Kageyama, Antonella Casamassa

Publikováno v: Karow, M, Camp, J G, Falk, S, Gerber, T, Pataskar, A, Gac-Santel, M, Kageyama, J, Brazovskaja, A, Garding, A, Fan, W, Riedemann, T, Casamassa, A, Smiyakin, A, Schichor, C, Götz, M, Tiwari, V K, Treutlein, B & Berninger, B 2018, ' Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program ', Nature Neuroscience, vol. 21, no. 7, pp. 932–940 . https://doi.org/10.1038/s41593-018-0168-3
Nat. Neurosci. 21, 932–940 (2018)
Nature Neuroscience
Nature Neuroscience, 21 (7)
Nature neuroscience

Ectopic expression of defined transcription factors can force direct cell-fate conversion from one lineage to another in the absence of cell division. Several transcription factor cocktails have enabled successful reprogramming of various somatic cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1946f77c6a169a8af4c30f18efafe13f
https://kclpure.kcl.ac.uk/ws/files/97577878/Karow_et_al_final_version.pdf