Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Braxton Harris"'
Autor:
Carli K. Opland, Miles R. Bryan, Braxton Harris, Jake McGillion-Moore, Xu Tian, Youjun Chen, Michelle S. Itano, Graham H. Diering, Rick B. Meeker, Todd J. Cohen
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106905- (2023)
Summary: Tau-mediated toxicity is associated with cognitive decline and Alzheimer’s disease (AD) progression. In particular, tau post-translational modifications (PTMs) are thought to generate aberrant tau species resulting in neuronal dysfunction.
Externí odkaz:
https://doaj.org/article/b7f1210596e04e69bf9b211b6c093c4c
RTEL-1 and DNA polymerase theta promote subtelomeric DNA synthesis and telomere fusion in C. elegans
Autor:
Evan H. Lister-Shimauchi, Morgan Brady, Stephen Frenk, Braxton Harris, Ana-Maria Leon Ortiz, Aylin Memili, Minh Nguyen, Simon Boulton, Shawn Ahmed
Interstitial telomere sequences (ITS) are degenerate telomere tracts scattered along chromosome arms whose functions are not well understood. We found that critically shortened telomeres of C. elegans telomerase mutants initiate DNA synthesis within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d47b8169c9bce95757b5879ade386a6b
https://doi.org/10.1101/2022.09.04.506531
https://doi.org/10.1101/2022.09.04.506531
