Phase variation of a Type IIG restriction-modification enzyme alters site-specific methylation patterns and gene expression in Campylobacter jejuni strain NCTC11168

Autor: Anjum, Awais, Brathwaite, Kelly J., Aidley, Jack, Connerton, Phillippa L., Cummings, Nicola J., Parkhill, Julian, Connerton, Ian, Bayliss, Christopher D.

Publikováno v: Nucleic Acids Research

Phase-variable restriction-modification systems are a feature of a diverse range of bacterial species. Stochastic, reversible switches in expression of the methyltransferase produces variation in methylation of specific sequences. Phase-variable meth

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http://eprints.nottingham.ac.uk/31382/

Phase variation of a Type IIG restriction-modification enzyme alters site-specific methylation patterns and gene expression in Campylobacter jejuni strain NCTC11168.

Autor: Anjum A; Department of Genetics, University of Leicester, Leicester LE1 7RH, UK., Brathwaite KJ; Division of Food Sciences, School of Biosciences, University of Nottingham, Sutton Bonington LE12 5RD, UK., Aidley J; Department of Genetics, University of Leicester, Leicester LE1 7RH, UK., Connerton PL; Division of Food Sciences, School of Biosciences, University of Nottingham, Sutton Bonington LE12 5RD, UK., Cummings NJ; Division of Food Sciences, School of Biosciences, University of Nottingham, Sutton Bonington LE12 5RD, UK., Parkhill J; The Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Connerton I; Division of Food Sciences, School of Biosciences, University of Nottingham, Sutton Bonington LE12 5RD, UK., Bayliss CD; Department of Genetics, University of Leicester, Leicester LE1 7RH, UK cdb12@le.ac.uk.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2016 Jun 02; Vol. 44 (10), pp. 4581-94. Date of Electronic Publication: 2016 Jan 18.