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pro vyhledávání: '"Bratati Saha"'
Autor:
Bratati Saha, Robin J. Parks
Publikováno v:
Microorganisms, Vol 8, Iss 9, p 1284 (2020)
Human adenovirus (HAdV) is a very common pathogen that typically causes minor disease in most patients. However, the virus can cause significant morbidity and mortality in certain populations, including young children, the elderly, and those with com
Externí odkaz:
https://doaj.org/article/c4ef5474286546f58c729096db48d42c
Autor:
Bratati Saha, Robin J Parks
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181012 (2017)
Adenovirus (Ad) vectors deleted of the early region 1 (E1) are widely used for transgene delivery in preclinical and clinical gene therapy studies. Although proteins encoded within the E1 region are required for efficient virus replication, previous
Externí odkaz:
https://doaj.org/article/c8fafc8dbaff4940a8faff14d785a2d3
Publikováno v:
Viruses, Vol 6, Iss 9, Pp 3563-3583 (2014)
Adenovirus (Ad) vectors are currently the most commonly used platform for therapeutic gene delivery in human gene therapy clinical trials. Although these vectors are effective, many researchers seek to further improve the safety and efficacy of Ad-ba
Externí odkaz:
https://doaj.org/article/6797784dc99d4a4ab917e4eaad673c85
Publikováno v:
Virology. 538:24-34
Human adenovirus (HAdV) can cause severe disease and death in both immunocompromised and immunocompetent patients. The current standards of treatment are often ineffective, and no approved antiviral therapy against HAdV exists. We report here the des
Autor:
Andrea N. Giberson, Bratati Saha, Kalisa Campbell, Robin J. Parks, Carin Christou, Kathy L. Poulin
Publikováno v:
Biochemistry and Cell Biology. 96:797-807
Adenovirus (Ad) DNA undergoes dynamic changes in protein association as the virus progresses through its replicative cycle. Within the virion, the Ad DNA associates primarily with the virus-encoded, protamine-like protein VII. During the early phase
Autor:
Bratati Saha, Robin J. Parks
Publikováno v:
Virology
Human adenovirus (HAdV) can cause severe disease in certain at-risk populations such as newborns, young children, the elderly and individuals with a compromised immune system. Unfortunately, no FDA-approved antiviraldrug is currently available for th
Autor:
Bratati Saha, Robin J. Parks
Publikováno v:
Journal of Virology. 93
Human adenovirus (HAdV) causes minor illnesses in most patients but can lead to severe disease and death in pediatric, geriatric, and immunocompromised individuals. No approved antiviral therapy currently exists for the treatment of these severe HAdV
Autor:
Bratati Saha, Aaron Hinz, Sarah J. Copeland, Li Zhang, Jean-Paul Nadeau, Thien-Fah Mah, Clayton W. Hall, Luke B.-P. Gagnon
Publikováno v:
Applied and Environmental Microbiology. 84
Chronic, biofilm-based bacterial infections are exceptionally difficult to eradicate due to the high degree of antibiotic recalcitrance exhibited by cells in biofilm communities. In the opportunistic pathogen Pseudomonas aeruginosa , biofilm recalcit
Publikováno v:
Viruses, Vol 6, Iss 9, Pp 3563-3583 (2014)
Viruses
Viruses
Adenovirus (Ad) vectors are currently the most commonly used platform for therapeutic gene delivery in human gene therapy clinical trials. Although these vectors are effective, many researchers seek to further improve the safety and efficacy of Ad-ba