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ADAM9 promotes type I interferon-mediated innate immunity during encephalomyocarditis virus infection.

Autor: Bazzone LE; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA.; Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Zhu J; Florida Research and Innovation Center, Cleveland Clinic, Port St Lucie, FL, USA., King M; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Liu G; Florida Research and Innovation Center, Cleveland Clinic, Port St Lucie, FL, USA., Guo Z; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA., MacKay CR; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Kyawe PP; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Qaisar N; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Rojas-Quintero J; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Owen CA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Brass AL; Department of Microbiology and Physiological Systems, University of Massachusetts Chan Medical School, Worcester, MA, USA., McDougall W; Department of Microbiology and Physiological Systems, University of Massachusetts Chan Medical School, Worcester, MA, USA., Baer CE; Department of Microbiology and Physiological Systems, University of Massachusetts Chan Medical School, Worcester, MA, USA., Cashman T; Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Trivedi CM; Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Gack MU; Florida Research and Innovation Center, Cleveland Clinic, Port St Lucie, FL, USA., Finberg RW; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA.; Program in Innate Immunity, University of Massachusetts Chan Medical School, Worcester, MA, USA., Kurt-Jones EA; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA. Evelyn.Kurt-Jones@umassmed.edu.; Program in Innate Immunity, University of Massachusetts Chan Medical School, Worcester, MA, USA. Evelyn.Kurt-Jones@umassmed.edu.

Publikováno v: Nature communications [Nat Commun] 2024 May 16; Vol. 15 (1), pp. 4153. Date of Electronic Publication: 2024 May 16.

Frequent Loss of IRF2 in Cancers Leads to Immune Evasion through Decreased MHC Class I Antigen Presentation and Increased PD-L1 Expression.

Autor: Kriegsman BA; Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655., Vangala P; Department of Bioinformatics and Computational Biology, University of Massachusetts Medical School, Worcester, MA 01655., Chen BJ; Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655., Meraner P; Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01655., Brass AL; Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01655.; Department of Medicine, Gastroenterology Division, University of Massachusetts Medical School, Worcester, MA 01655; and.; Peak Gastroenterology Associates, Colorado Springs, CO 80907., Garber M; Department of Bioinformatics and Computational Biology, University of Massachusetts Medical School, Worcester, MA 01655., Rock KL; Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655; Kenneth.Rock@umassmed.edu.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2019 Oct 01; Vol. 203 (7), pp. 1999-2010. Date of Electronic Publication: 2019 Aug 30.