Towards a Better Understanding of Verapamil Release from Kollicoat SR:IR Coated Pellets Using Non-Invasive Analytical Tools

Autor: Julie Fahier, Branko Vukosavljevic, Laure De Kinder, Hugues Florin, Jean-François Goossens, Maike Windbergs, Florence Siepmann, Juergen Siepmann, Susanne Muschert

Publikováno v: Pharmaceutics, Vol 13, Iss 10, p 1723 (2021)

The aim of this study was to gain deeper insight into the mass transport mechanisms controlling drug release from polymer-coated pellets using non-invasive analytical tools. Pellet starter cores loaded with verapamil HCl (10% loading, 45% lactose, 45

Externí odkaz: https://doaj.org/article/0a9fdf2949974371a88bf31daa46613f

Towards a Better Understanding of Verapamil Release from Kollicoat SR:IR Coated Pellets Using Non-Invasive Analytical Tools

Autor: Florence Siepmann, Laure De Kinder, Maike Windbergs, Julie Fahier, S. Muschert, Hugues Florin, Branko Vukosavljevic, Jean-François Goossens, Juergen Siepmann

Publikováno v: Pharmaceutics
Pharmaceutics, 2021, Pharmaceutics, 13 (10), pp.1723. ⟨10.3390/pharmaceutics13101723⟩
Pharmaceutics, Vol 13, Iss 1723, p 1723 (2021)
Volume 13
Issue 10

International audience; The aim of this study was to gain deeper insight into the mass transport mechanisms controlling drug release from polymer-coated pellets using non-invasive analytical tools. Pellet starter cores loaded with verapamil HCl (10%

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895da737441163dfae02efdb13075ada
https://hal.univ-lille.fr/hal-03621350

Tracing molecular and structural changes upon mucolysis with N-acetyl cysteine in human airway mucus

Autor: Xabier Murgia, Maike Windbergs, Branko Vukosavljevic, Claus-Michael Lehr, Konrad Schwarzkopf, Ulrich F. Schaefer

Publikováno v: International Journal of Pharmaceutics. 533:373-376

The conducting airways of the human lungs are lined by mucus, which lubricates the lung epithelium and provides a first-line protection against airborne threats. As a novel approach for visualization of the human mucus microstructure, we applied conf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab224a16c1532ad1fb40f42cea323b2
https://doi.org/10.1016/j.ijpharm.2017.07.022

Synthesis of a deuterated probe for the confocal Raman microscopy imaging of squalenoyl nanomedicines

Autor: Branko Vukosavljevic, Didier Desmaële, Camille Dejean, Dunja Sobot, Patrick Couvreur, Maike Windbergs, Simona Mura, Eric Buchy

Publikováno v: Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 1127-1135 (2016)
Beilstein Journal of Organic Chemistry

The synthesis of ω-di-(trideuteromethyl)-trisnorsqualenic acid has been achieved from natural squalene. The synthesis features the use of a Shapiro reaction of acetone-d6 trisylhydrazone as a key step to implement the terminal isopropylidene-d6 moie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db80d0d53e2cfef7b54521be9e917777
https://doaj.org/article/ca6546c5702a4a8e85884370f5dd5ce2

Vibrational spectroscopic imaging and live cell video microscopy for studying differentiation of primary human alveolar epithelial cells

Autor: Thomas R Huser, Xabier Murgia, Christian Pilger, Hanno Huwer, Branko Vukosavljevic, Luca Gentile, Claus-Michael Lehr, Michael M. Gepp, Henning Hachmeister, Nicole Schneider-Daum, Marius Hittinger, Maike Windbergs

Publikováno v: e201800052
Journal of biophotonics
International
Germany

Alveolar type II (ATII) cells in the peripheral human lung spontaneously differentiate toward ATI cells, thus enabling air‐blood barrier formation. Here, linear Raman and coherent anti‐Stokes Raman scattering (CARS) microscopy are applied to stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed7ab05094a712605c178c1ca236e4f
https://pubmed.ncbi.nlm.nih.gov/30597770