Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Branko Kurelec"'
Publikováno v:
Ecotoxicology. 9:307-327
Aquatic organisms are inherently equipped with a mechanism that rescues them by pumping potentially toxic xenobiotics out of the cells before they express their deleterious potential. The presence of this multixenobiotic resistance (MXR) mechanism ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbc2583f2ee55b0ee23ca2237249ac03
https://doi.org/10.1023/a:1026560922731
https://doi.org/10.1023/a:1026560922731
Publikováno v:
Marine Environmental Research. 46:415-419
The protective function of multixenobiotic resistance (MXR) mechanism in aquatic organisms can be inhibited by many chemical compounds, the chemosensitizers. The presence of these MXR-inhibitors has important implications on environmental parameters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6ca617ed0b687a611e80edb7115c5c
https://doi.org/10.1016/s0141-1136(97)00065-2
https://doi.org/10.1016/s0141-1136(97)00065-2
Autor:
Branko Kurelec, Tvrtko Smital
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 399:43-53
Mechanism of multixenobiotic resistance (MXR), identical to multidrug resistance (MDR) in tumor cells, has been found in aquatic invertebrates. The presence of this ATP-dependent membrane P-glycoprotein (Pgp) pump was confirmed by biochemical (`bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8781c65557ab516617b10fd085bd71
https://doi.org/10.1016/s0027-5107(97)00265-0
https://doi.org/10.1016/s0027-5107(97)00265-0
Autor:
Farid A. Badria, Werner E.G. Müller, Matthias Wiens, Heinz C. Schröder, Seif N Ayyad, Hamdy M.A Hassanein, Branko Kurelec, Renato Batel
Publikováno v:
Environmental Toxicology and Pharmacology. 5:119-126
The invasive growth of the introduced green alga Caulerpa taxifolia, already affecting the richness and diversity of the littoral ecosystems, has become a major ecological problem in the Mediterranean Sea. Previously, we demonstrated that the water p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93605e271b31088f68aadae42975bedd
https://doi.org/10.1016/s1382-6689(97)10067-9
https://doi.org/10.1016/s1382-6689(97)10067-9
Autor:
Branko Kurelec, Tvrtko Smital
Publikováno v:
Environmental Toxicology and Chemistry. 16:2164-2170
Xenobiotics in water that can inhibit the multixenobiotic resistance (MXR) defense mechanism in water organisms, the chemosensitizers, may cause severe ecotoxicological effects. We determined their concentrations in polluted and unpolluted river wate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3da58e8c4a2ef5540ec8857d1f87d756
https://doi.org/10.1002/etc.5620161025
https://doi.org/10.1002/etc.5620161025
Publikováno v:
Scopus-Elsevier
Experiments were carried out with the marine sponge Suberites domuncala to determine whether sponges may express - like mammalian tumor cells a multidrug-like transporter system. The results demonstrate that sponge cells possess such a protective sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c8df0b7cc6ad0d608d32a8a66408c2
https://doi.org/10.1007/bf00350770
https://doi.org/10.1007/bf00350770
Publikováno v:
Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology. 113:283-289
The gills of mussel Mytilus galloprovincialis express a multixenobiotic resistance mechanism (MXRM) mediated by P-glycoprotein activity, as evidenced by the rate of (G-3H) vincristine accumulation and its sensitivity to verapamil, as well as by the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14aaf4f7779ab899304116241bb0474d
https://doi.org/10.1016/0742-8413(96)84525-7
https://doi.org/10.1016/0742-8413(96)84525-7
Autor:
Branko Kurelec
Publikováno v:
Aquatic Toxicology. 33:93-103
In gills of the marine mussel Mytilus galloprovincialis there is a P-glycoprotein-mediated multixenobiotic resistance mechanism (MXRM) which is similar to the multidrug resistance (MDR) mechanism in tumor cells resistant to cytotoxic drugs. This mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::359b1d1d88fa67ed5e23332a7fc24da3
https://doi.org/10.1016/0166-445x(95)00010-2
https://doi.org/10.1016/0166-445x(95)00010-2
Autor:
Branko Kurelec, Jutta Dapper, Werner E.G. Müller, Baruch Rinkevich, Renato Batel, Claudia Koziol
Publikováno v:
Environmental Toxicology and Chemistry. 14:1203-1208
This is the first documentation of a heat shock protein (hsp) response in sponges. Subjecting the freshwater sponge Ephydatia fluviatilis to temperature stress (18 to 33 C; 2 h) resulted in an increased expression (>10 times) of the M{sub r}70,000 (h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd39f47e771a7f58cfea6eac6c3a55a1
https://doi.org/10.1002/etc.5620140712
https://doi.org/10.1002/etc.5620140712
Autor:
Branko Kurelec
Publikováno v:
Marine Environmental Research. 35:341-348
Since lower animals develop neoplasia rarely or not at all, the DNA- and chromosomal-alterations observed in them after exposure to genotoxic chemicals should be correlated to some genotoxic endpoint other than neoplasia. On the basis of good correla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4befd91474314e387e928bb221e894fb
https://doi.org/10.1016/0141-1136(93)90101-5
https://doi.org/10.1016/0141-1136(93)90101-5