Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Brandon Somerville"'
Autor:
Yurong Song, Travis D. Kerr, Chelsea Sanders, Lisheng Dai, Shaneen S. Baxter, Brandon Somerville, Ryan N. Baugher, Stephanie D. Mellott, Todd B. Young, Heidi E. Lawhorn, Teri M. Plona, Bingfang Xu, Lei Wei, Qiang Hu, Song Liu, Alan Hutson, Baktiar Karim, Sandra Burkett, Simone Difilippantonio, Ligia Pinto, Johannes Gebert, Matthias Kloor, Steven M. Lipkin, Shizuko Sei, Robert H. Shoemaker
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundGenome integrity is essential for the survival of an organism. DNA mismatch repair (MMR) genes (e.g., MLH1, MSH2, MSH6, and PMS2) play a critical role in the DNA damage response pathway for genome integrity maintenance. Germline mutations o
Externí odkaz:
https://doaj.org/article/0d2e5d6b71eb4b909e5643961c4ff61e
Autor:
Casey C. Perley, Rebecca L. Brocato, Hua Wu, Christoph Bausch, Priya P. Karmali, Jerel B. Vega, Melanie V. Cohen, Brandon Somerville, Steven A. Kwilas, Lucia M. Principe, Joshua Shamblin, Padmanabh Chivukula, Eddie Sullivan, Jay W. Hooper
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
We explored an emerging technology to produce anti-Hantaan virus (HTNV) and anti-Puumala virus (PUUV) neutralizing antibodies for use as pre- or post-exposure prophylactics. The technology involves hyperimmunization of transchomosomic bovines (TcB) e
Externí odkaz:
https://doaj.org/article/883066dd28aa42bfa06594256c084192
Autor:
Yurong Song, Shaneen Baxter, Lisheng Dai, Chelsea Sanders, Holli Loomans-Kropp, Brandon Somerville, Ryan N. Baugher, Stephanie D. Mellott, Todd B. Young, Heidi E. Lawhorn, Teri M. Plona, Bingfang Xu, Lei Wei, Qiang Hu, Song Liu, Alan Hutson, Baktiar Karim, Simone Difilippantonio, Ligia Pinto, Matthias Kloor, Steven M. Lipkin, Shizuko Sei, Robert H. Shoemaker
Publikováno v:
Cancer Research. 83:6518-6518
DNA mismatch repair (MMR) genes (e.g., MLH1, MSH2, MSH6, PMS2, and EPCAM) play an important role in maintaining genomic stability during DNA replication and recombination. Deficiency in MMR resulting from mutations in these genes leads to mutations i
Autor:
Christopher P. Klimko, Chris W Schellhase, Nancy A. Twenhafel, Jeremy A. Miller, Christopher K. Cote, Donald J. Chabot, John R. Barr, Susham S. Ingavale, Mary E. Wright, Nicholas J. Vietri, Adrian R. Woolfitt, David P Fetterer, Anne E. Boyer, Brandon Somerville, Arthur M. Friedlander, Steven A. Tobery
Publikováno v:
J Infect Dis
Background Inhalational anthrax is rare and clinical experience limited. Expert guidelines recommend treatment with combination antibiotics including protein synthesis-inhibitors to decrease toxin production and increase survival, although evidence i
Autor:
Casey C. Perley, Rebecca L. Brocato, Melanie V. Cohen, Brandon Somerville, Steven A. Kwilas, Lucia M. Principe, Simon Y Long, Xiankun Zeng, Jay W. Hooper, Matthew D. Josleyn
Publikováno v:
Vaccine. 39(7)
DNA vaccine evaluation in small animals is hampered by low immunogenicity when the vaccines are delivered using a needle and syringe. To overcome this technical hurdle we tested the possibility that a device developed for human intradermal medicine d
Autor:
B Hill, Connie S. Schmaljohn, Melanie V. Cohen, Brandon Somerville, M Wisniewski, Mariano Sanchez-Lockhart, K Mills, Kristopher M. Paolino, Drew Hannaman, Jay W. Hooper, Matthew D. Josleyn, Steven A. Kwilas, Shane A. Norris
Publikováno v:
Vaccines, Vol 8, Iss 377, p 377 (2020)
Vaccines
Volume 8
Issue 3
Vaccines
Volume 8
Issue 3
Hantaan virus (HTNV) and Puumala virus (PUUV) are pathogenic hantaviruses found in Asia and Europe, respectively. DNA vaccines targeting the envelope glycoproteins of these viruses have been constructed and found to elicit neutralizing antibodies whe
Autor:
Melanie V. Cohen, Joshua D. Shamblin, Jay W. Hooper, Eddie Sullivan, Rebecca L. Brocato, Padmanabh Chivukula, Lucia M. Principe, Brandon Somerville, Christoph L Bausch, Steven A. Kwilas, Jerel Vega, Priya Karmali, Hua Wu, Casey C. Perley
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Frontiers in Microbiology
Frontiers in Microbiology
We explored an emerging technology to produce anti-Hantaan virus (HTNV) and anti-Puumala virus (PUUV) neutralizing antibodies for use as pre- or post-exposure prophylactics. The technology involves hyperimmunization of transchomosomic bovines (TcB) e
Autor:
Jeremy A. Miller, Elizabeth Wasbrough, Brandon Somerville, Floyd E. Romesberg, Stephanie Halasohoris, Jian Liu, Danielle Barrios Steed, Lynda Miller, Jeremy R. Hershfield
Publikováno v:
Antimicrobial agents and chemotherapy. 59(7)
Yersinia pestis is the etiologic agent of the plague. Reports of Y. pestis strains that are resistant to each of the currently approved first-line and prophylactic treatments point to the urgent need to develop novel antibiotics with activity against